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Biomedical subjects

H B Griffith

Publications and source records attributed to H B Griffith.

15 recordsLinked to original sources
PubMed1991

Objective and subjective memory impairment in pregnancy.

Pregnant subjects rated their memories as worse than normal and their ratings differed significantly from controls. Explicit memory tested by both recognition and recall was unimpaired. In contrast, implicit memory was significantly impaired in primigravidae. Impairment in implicit memory correlated with the subjective memory ratings. The dissociation of explicit and implicit memory is discussed.

Adult↗
PubMed1990

The treatment of childhood hydrocephalus by choroid plexus coagulation and artificial cerebrospinal fluid perfusion.

The authors report their experience in the treatment of childhood hydrocephalus by endoscopic choroid plexus coagulation and post-operative ventricular perfusion with artificial CSF. The procedure was carried out on 23 children without mortality. In 12 cases (52%) the procedure was successful in controlling the hydrocephalus. The average follow-up was 2.3 years. Eleven cases (48%) required shunting which was done from 1 week to 13 months following the choroid plexus coagulation. As cure of the hydrocephalus was achieved in over half of the patients, the authors recommend the procedure as a first line treatment for childhood hydrocephalus.

Cerebrospinal Fluid↗
PubMed1990

Microdiscectomy.

Despite the introduction of microdiscectomy some fifteen years ago, the spread of this procedure amongst surgeons who operate on discs has been disappointingly slow. The overall impression of the impact which this operation has made on the surgery of lumbar discs is considerable and the authors recommend that this should now be the standard operation for disc sciatica, especially as the operation can now be performed as an outpatient procedure.

Ambulatory Surgical Procedures↗
PubMed1988

Trophoblast membrane infusion for unexplained recurrent miscarriage.

A novel protocol is described which has been developed for immunotherapy in unexplained recurrent miscarriage. This is based on a single intravenous infusion with isolated placental trophoblast plasma membrane vesicle preparations. Clinical experience gained with this approach is described. A total of 16/21 (76%) patients who subsequently had pregnancies have now achieved a live birth or are currently pregnant at greater than 28 weeks gestation.

Abortion, Habitual↗
PubMed1987

A direct transnasal approach to the sphenoid sinus. Technical note.

The transsphenoidal route to the pituitary gland is well established in neurosurgical practice, and several approaches to the sphenoidal air sinus have been described. In this paper, the authors describe a technique that utilizes a direct route through the nasal cavity, thereby minimizing disruption of normal tissues.

Humans↗
PubMed1985

Intimal dissection following percutaneous transluminal carotid angioplasty for fibromuscular dysplasia.

Fibromuscular dysplasia (FMD) is an unusual form of segmental arteriopathy and may affect the internal carotid artery (ICA). We report a case of carotid FMD in which percutaneous transluminal angioplasty (PTA) was complicated by an intimal tear and required surgical exploration. PTA is a useful form of treatment, but there is a risk of intimal dissection. If this occurs, it may be necessary to excise the intimal flap surgically.

Adult↗
PubMed1976

Management of the uninhibited bladder by selective sacral neurectomy.

The authors report the treatment of incontinence due to uninhibited bladder contractions by selective sacral neurectomy in nine patients, four without evidence of neurological disease. A detailed and objective analysis of bladder and urethral function, together with quantitation of clinical features, was made before and after operation. Seven patients were either cured or greatly improved. The overall increase in bladder capacity and reduction of uninhibited activity were statistically significant. The resting urethral sphincter pressure was unchanged, but the contractility of the voluntary external sphincter was slightly impaired. Criteria for such neurectomies are discussed.

Anesthesia, Caudal↗
PubMed1975

Technique of fontanelle and persutural ventriculoscopy and endoscopic ventricular surgery in infants.

The author describes a new type of neurosurgical operating telescope which makes possible the foundation of endoneurosurgery. Illumination through a fibre-optic bundle and image transmission through a series of coated air lenses in glass are based on Hopkins optical systems. The telescope is 2.6 mm in external diameter. The operating sheath introduced around the telescope by means of split obturators which dilate the telescope track, enlarges the external diameter of the instrument to 4.5 mm. Up to four special instruments (electrode, aspirating cannula, accessory light, perfusing cannula, scissors) or a grasping forceps can be introduced through the instrument sheath. The instrument can be introduced, using a sharp trocar, through the fontanelle or lambdoid suture in infants and through a burr hole in children. It has been used for third ventriculoscopy and choroid plexus coagulation. The latter has been carried out successfully through the anterior fontanelle and the lambdoid suture, bilaterally in 2-4 stages. Complications - one meningitis - have been the exception.

Cerebral Ventricles↗