Search PubMed⌕ Search

Biomedical subjects

H B Cohen

Publications and source records attributed to H B Cohen.

26 records · Page 2Linked to original sources
PubMed1966

Sleep: suppression of rapid eye movement phase in the cat after electroconvulsive shock.

Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatlyreduced. Although partially deprived of rapid eye movements for as long as 7 days, the cats showed no compensatory rise in rapid eye movement time during the recovery period, but controls equally deprived gave significant rebounds. Rapid eye movement time of anesthetized cats was not affected by current that usually produces con vulsions; it was lowered in animals convulsed with metrazol, but the same dosage of this drug, administered so as to avoid convulsions, had little eflect. It appears that some aspect of the convulsion is responsible for lowering the rapid eye movement time.

Animals↗
PubMed1965

Sleep: changes in threshold to electroconvulsive shock in rats after deprivation of "paradoxical" phase.

Rats were deprived of paradoxical (radid eye movement or REM) sleep for a 6-day period but were allowed substantial non-REM (slow wave) sleep. Thresholds for electroconvulsive shock dropped significantly after deprivation in all these animals, but thresholds in control animals treated in a similar manner, but allowed REM sleep exhibited no change. Deprivation seems to heighten neural excitability.

Animals↗
PubMedDate not supplied

Acute pulmonary edema following head injury: two case reports.

An acute episode of pulmonary edema may occur in association with head injury. This is due to the elevation of systemic blood pressure, to maintain cerebral circulation in the presence of increasing intracranial pressure (ICP). In these instances, the pulmonary edema arises as a pathophysiologic, neurohemodynamic response to the intracranial disease. This response has been produced experimentally, and 2 case reports described this problem clinically. If such patients with increased ICP could be treated immediately with antihypertensive drugs, pulmonary edema might be prevented and the high mortality rate decreased.

Acute Disease↗