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Biomedical subjects

H Aubert

Publications and source records attributed to H Aubert.

At least 37 records · Page 2Linked to original sources

[Endocrine consequences of corticotherapy. Weaning from long-term corticotherapy].

Long term corticosteroid therapy has multiple effects on the endocrine system. These include adrenocortical suppression in high doses, alteration of gonadotropic and gonadal secretion, slowing down of long bone growth and bone maturation in children, osteoporosis in adults, alteration of the thyrotropic function and changes in thyroxine peripheral metabolism, diabetogenic effect. The list is not exhaustive, and there are more complex effects on the secretion of prolactin, pancreatic peptides, VIP, etc. Because of these various effects, the pros and cons of long term corticosteroid therapy must be carefully weighted, and if it is necessary steroids should be prescribed in such a way as to limit their side-effects: at best one dose taken in the morning every other day, together with the prescription of calcium, of a salt-free diet and, in some cases, of androgens or oestrogens. Weaning must be carried out with caution, to avoid rebound of the disease treated, and with substitution of hydrocortisone when the corticosteroid dosage reaches 5 mg per day of prednisone or equivalent and can be interrupted. The functional soundness or alteration of the corticotropic and adrenal functions must then be evaluated by testing corticotropic and adrenal functions must then be evaluated by testing the adrenocortical response to tetracosactrin, or even better by measuring early morning concentrations of blood cortisol. Depending on the results obtained, hydrocortisone can be withdrawn and limited to episodes of stress, or continued until ACTH and endogenous cortisol levels have returned to normal values.

Adrenal Cortex Hormones↗

[The CO2 laser and gingivoplasty].

The CO2 laser has here been used in comparison with the electric bistoury during a gingivoplasty joined to a subgingival scaling. The healing up and the result - in a short as well as in a long length of time - are the same. This type of laser can then be used in this sort of treatment despite the fact that it does not bring any particular advantages.

Electrosurgery↗

[Lyophilized dura in covering of filled sites].

When closing is difficult to obtain in a filled site at the end of the surgical phase, the use of dried-dura-mater (connective tissue of the brain external envelope) can be very helpful. Placed under a full thickness flap or sutured on a periosteal site, it is, after a week, already continuous with tissues and helps for a good closing. The dura-mater can be shaped and cut differently according to specific clinical situations.

Biological Dressings↗

[Frena].

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Adult↗