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H Atsumi

Publications and source records attributed to H Atsumi.

53 records · Page 3Linked to original sources

[Transseptal suture fixation in the management of prosthetic valve dehiscence].

Valve dehiscence resulted from prosthetic valve endocarditis and aortitis is the most common cause of the reoperation after prosthetic valve replacement. In our experience, the results of reoperation has been far from satisfactory. For the successful management of prosthetic dehiscence, we have adopted the transseptal suture technique of accurately securing the prosthetic valve. Five patients with prosthetic valve dehiscence and one patient with native valve endocarditis were operated upon using the transseptal techniques. Left ventricular-aortic discontinuity was repaired using composite valve-tube graft together with this technique in two patients. All but one patient who succumbed to multiple organ failure induced by preoperative hemodynamic deterioration have survived the operation without recurrent infective endocarditis or valve dehiscence.

Adult↗

[Circadian rhythm of urinary somatostatin-like immunoreactivity (SLI) and its contents in several organs after oral TRH administration in rats].

Urinary SLI was measured every six hours for twenty four hours in rats fed a regular diet. Previously, we found that the urinary SLI increased after the administration of TRH intravenously. In the present study, in order to reveal the localization of increased SLI, we measured the contents in the hypothalamus, pituitary, thyroid, stomach and pancreas after the oral TRH administration. (1) The rat urinary SLI levels showed a circadian rhythm. The maximum level of SLI was collected from 0.00--6.00 a.m. (89.4 +/- 8.6 pg/6 hrs) (mean +/- SEM). This level was reduced during the daytime 6.00 a.m.--6.00 p.m. The minimum level was obtained from 6.00 p.m.--0.00 a.m. (49.3 +/- 7.2 pg/6 hrs). (2) The rats were decapitated at three and six hours after the oral TRH (500 micrograms/ml) administration. The SLI content was measured by RIA after extraction from each organ with 2.5 ml of 2 M acetic acid. The pituitary SLI content was reduced three hours after the oral TRH administration. The thyroid SLI content was reduced six hours after the oral TRH administration. The hypothalamic, gastric and pancreatic SLI contents didn't change at three and six hours after the oral TRH administration. As the result, the data suggest that augmentation by the oral TRH administration of urinary SLI was caused by its effect on the both the pituitary and the thyroid.

Administration, Oral↗

[Neurotensin].

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Adult↗

Prediction of functional recovery in acute myocardial infarction: comparison between sestamibi reverse redistribution and sestamibi/BMIPP mismatch.

BACKGROUND: It has been known that Tc 99m sestamibi/iodine 123 betamethyliodophenylpentadecanoic (123I-BMIPP) (sestamibi/BMIPP) mismatch is an indicator of viable myocardium in acute myocardial infarction (AMI). We have reported that reverse redistribution of sestamibi in AMI indicates the patency of infarct-related artery and a preserved left ventricular function in the chronic stage. In this study we investigated the relationship between reverse redistribution of sestamibi and sestamibi/BMIPP mismatch in patients with AMI. METHODS: Twenty-three patients with AMI who received direct percutaneous transluminal coronary angioplasty underwent both BMIPP and sestamibi SPECT within 2 weeks after onset. Sestamibi images were obtained 1 hour (early) and 3 hours (delayed) after injection of sestamibi. BMIPP imaging was carried out 30 minutes after injection. The left ventricle was divided into 17 segments, and regional myocardial uptakes of the tracers in each segment were scored from 0 (normal) to 3 (no activity). A reverse redistribution pattern was defined as an increase of > or =1 in the regional score at the delayed images. More reduced BMIPP uptake than sestamibi uptake in each segment was determined as sestamibi/BMIPP mismatch. Contrast left ventriculography was performed soon after revascularization and repeated 1 month later. RESULTS: Of 15 patients with sestamibi reverse redistribution, sestamibi/BMIPP mismatch was observed in 14 patients (93%), whereas mismatch was seen in only one of seven patients (14%) without reverse redistribution (p < 0.01). In patients with sestamibi reverse redistribution, regional scores of BMIPP agreed with those of early and delayed images of sestamibi in 51 segments (46%) and in 92 segments (83%), respectively. In the chronic stage, both regional wall motion and left ventricular ejection fraction improved in patients with sestamibi reverse redistribution (wall motion score: 6.7 +/- 2.4 vs 2.7 +/- 2.1, p < 0.01; ejection fraction: 56% +/- 7% vs 64% +/- 8%, p < 0.01), but not in those without reverse redistribution. CONCLUSION: Both reverse redistribution of sestamibi and sestamibi/BMIPP mismatch reflect the recovery of left ventricular function and thus imply myocardial viability in AMI. Because the presence of reverse redistribution of sestamibi agreed with that of sestamibi/BMIPP mismatch, additional BMIPP images can be replaced by the delayed images after a single injection of sestamibi.

Aged↗