Search PubMed⌕ Search

Biomedical subjects

H Armstrong

Publications and source records attributed to H Armstrong.

At least 19 recordsLinked to original sources
PubMed1995

Fear and denial: grappling with the reality of abusive physicians.

The release in 1991 of the findings of the College of Physicians and Surgeons of Ontario Task Force on Sexual Abuse of Patients created a furore in the media and was met with denial and anger by many physicians. The publication in this issue (see pages 169 to 176) of Cohen and associates' survey on the impact of the task force report and the legislation that it prompted on the attitudes of recently certified family physicians provides an occasion for the author to reflect on the painful lessons that were learned in the course of the task force's inquiry.

Canada↗
PubMed1992

The Agescale.

Explore the source record for details and available documents.

Anthropometry↗
PubMed1988

Interpretation of single band patterns in CSF protein electrophoresis.

We have examined the diagnostic significance of finding one band in the immunoglobulin (IgG) region in spinal fluid protein electrophoresis. From January 1983 to January 1986, 855 consecutive CSF electrophoreses were performed on as many patients. A blinded observer identified a single band in the IgG region in 53 cases (6.2%). In only 14 patients (26%), were the clinical features ultimately felt to be due to clinically definite or possible multiple sclerosis (MS). The majority of patients with a single band had another neurological diagnosis (55%) or were neurologically normal (6%). Many of the neurological disorders in which a single band was found were not disorders in which an increased intrathecal synthesis of immunoglobulin or electrophoretic restriction would have been expected. A variety of conditions can produce a single band pattern. The significance of these patterns and the means by which they might be identified are described.

Brain Diseases↗
PubMed1982

Circumcision.

Explore the source record for details and available documents.

Circumcision, Male↗
PubMed1982

Variation in immunoglobulin G and albumin concentrations during lumbar CSF removal: a reappraisal.

We studied the variation in immunoglobulin G (IgG) and albumin concentrations in serial sampling of the first 25 ml of CSF during lumbar puncture (LP). A linear decremental gradient averaged 15% for both IgG and albumin. Both direction and magnitude of the gradient were unaffected by the position of the patient. In 12 patients with MS, the CSF IgG: albumin quotient was 5.5% greater when computed from the last aliquot, but this difference was not significant. These protein gradients affect the absolute concentrations but arae not likely to affect the interpretation of immunoglobulin indices or electrophoresis patterns.

Albumins↗
PubMed1980

Preparative isoelectric focusing in agarose.

A method is described for preparative isoelectric focusing in agarose using low electroendosmotic agarose. Resolution comparable to that seen on analytical polyacrylamide gels is attainable as demonstrated by the isolation of bands with identical idiotypes from the serum of a patient with a monoclonal gammopathy.

Electrophoresis, Agar Gel↗
PubMed1980

Hepatic infarction in ulcerative colitis during pregnancy.

Acute hepatic failure developed at the time of parturition in a 27-yr-old woman. Liver biopsy demonstrated disseminated hepatic infarctions which were confined to the distal segments of the hepatic microcirculatory units. This episode of hepatic infarction was followed by persistent fever and cutaneous vasculitis, which resolved on prednisone therapy. The diagnosis of ulcerative colitis was made 5 mo after recovery from severe hepatic failure.

Adult↗
PubMed1977

Prevention of experimental allergic encephalitis in guinea-pigs with spinal cord protein: optimum pretreatment schedules and appraisal of plausible mechanisms.

Pretreatment of Hartley guinea-pigs with three injections of 100 microgram of the purified bovine spinal cord protein, (SCP), protected tham from clinical experimental allergic encephalitis (EAE) when they were subsequently challenged with 50 microgram of purified bovine myelin basic protein (MyBP) in Freund's complete adjuvant (FCA). The length of the optimum pretreated schedule was found to be 1 week and the animals were fully protected for 2 weeks. Protection declined thereafter so that by 4 weeks following pretreatment only 40% of the animals were protected. The protected state could be restored several weeks after it had lapsed by repeating the treatment with SCP. Immature animals did not respond well to pretreatment with SCP. Evidence was presented to indicate that specific, non-specific immune suppression or anti-SCP IgG were not involved to a significant extent in protection. SCP-treated guinea-pigs regularly displayed delayed skin hypersensitivity to MyBP after sensitization but there was no correlation between the degree of cutaneous reactivity and protection from disease. Because SCP is localized in the nerve axon, the speculation was advanced that anti-SCP blocking factors might be responsible for preserving axonal function in SCP-treated animals sensitized with MyBP.

Animals↗