Azimuthal Decorrelation of Jets Widely Separated in Rapidity.
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Biomedical subjects
Publications and source records attributed to H Aihara.
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BACKGROUND AND OBJECTIVE: Although pulsed dye laser has been successfully used in the treatment of portwine stains, a number of patients had incomplete clearance because the depth of penetration by the pulsed dye laser was inadequate. This study was performed to establish the greater penetration depth of vascular injury using a dye-enhanced laser technique. STUDY DESIGN/MATERIALS AND METHODS: The ruby laser at 694.3 nm was used, and the corresponding specific dye was Prussian blue solution (maximum absorbance 694 nm). We compared the penetration depth of vascular injury by the ruby laser irradiation after the Prussian blue injection with that by the dye laser irradiation. A flashlamp dye laser with a pulse duration of 300 microseconds and a 5 mm diameter spot size was used to 6.2 J/cm2 at 590 nm. The Prussian blue solution was injected into the superficial epigastric artery of white male Japanese rabbits, immediately followed by the ruby laser exposure to 6.2 J/cm2 at a pulse duration of 283 microseconds in a 15 x 15 mm spotsize. Depth of penetration was measured from the dermoepidermal junction to the deepest site of vascular injury at 24 hours after laser exposure. RESULTS: Mean penetration of 590 nm of the dye laser light was 1.45 mm; mean penetration of the 694.3 nm ruby laser irradiation after the Prussian blue injection was 2.33 mm. Ruby laser penetration was greater than that of the dye laser. CONCLUSION: This study emphasizes that the ruby laser irradiation after the Prussian blue injection can induce deeper vascular injury than the dye laser inducing similar pathological changes.
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A 33-year-old woman was admitted to our hospital with acromegalic face as her chief complaint. Her neurological examination was normal, and endocrinological examination revealed a high level of growth hormone (GH) (12.8 ng/ml). CT cisternography and MRI showed an enlarged empty sella and a pituitary tumor. We performed a transsphenoidal approach operation to remove the tumor and to repair the empty sella. The tumor, which was compressed to the lateral and posterior wall of the sella turcica by the empty sella, was totally removed by meticulous curetting. It was histologically diagnosed to be a pituitary adenoma. The empty sella was elevated by coagulation of intrasellar dura and herniated arachnoid membrane, and then we filled the residual intrasellar cavity with bone fragments and fat. Postoperative hormonal examination showed normal findings, and MRI revealed obliteration of the empty sella. Surgical indication for primary empty sella is not established, but in cases associated with pituitary adenoma, transsphenoidal surgery is necessary. We reported a case of empty sella syndrome associated with GH secreting pituitary adenoma, and in this report, we introduced a new surgical technique for repairing an empty sella.
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