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Biomedical subjects

H Abramovici

Publications and source records attributed to H Abramovici.

150 records · Page 9Linked to original sources

Small for gestational age infants in pregnancies following jejunoileal bypass.

Two small for gestational age (SGA) infants resulting from pregnancies following jejunoileal bypass are described. Our two cases and five similar cases reported in medical literature are reviewed. It seems that SGA is the main problem in pregnancies following jejunoileal bypass. Adequate and careful monitoring of these pregnancies is advocated.

Adult↗

Pregnancy in the presence of an implanted pacemaker.

Two young females, who had implanted pacemakers, and experienced an uneventful course of pregnancy and delivery are described. We suggest the chest wall under the breasts as the site of choice for the implanted unit in young females who might expect pregnancy. If this site is used, any restriction of the skin above the unit should be prevented as the abdomen and breasts increase in size. The problem of a fixed heart rate during the period of an increasing work load on the heart in pregnancy is discussed, and the use in these patients of an adjustable-rate pulse-generators is suggested.

Adams-Stokes Syndrome↗

The use of a seminal vesicle specific protein (MHS-5 antigen) for diagnosis of agenesis of vas deferens and seminal vesicles in azoospermic men.

Azoospermia is the cause of infertility in 8% of infertile male patients. Ten percent of those patients suffer from agenesis of the seminal vesicle (SV) and vas deferens (VD) agenesis. Currently, the diagnosis of SV and VD agenesis is based on low semen volume, low pH, and low fructose content of the seminal fluid of azoospermic men who have normal serum gonadotropins. In this study, an SV-specific sperm-coating antigen, the MHS-5 antigen, was used as a marker for the presence of SVs. The SV-specific protein (SVSP), MHS-5, was present in the control group but was not found in any of the seven samples from azoospermic men with proven agenesis of SV and VD. Another semen component, the prostate-specific antigen (PSA), whose presence in the semen is not influenced by the SV and VD agenesis, was found in both the study and the control groups. Its presence ruled out the possibility of azoospermia due to ejaculatory duct obstruction. The absence of MHS-5 antigen in seminal fluid can be used as a tool for a reliable diagnosis of agenesis of SV and VD in azoospermic men.

Biomarkers↗

Pregnancies following treatment by GnRH-a (Decapeptyl) and myomectomy in infertile women with uterine leiomyomata.

PURPOSE: Uterine leiomyomata alone are an infrequent cause of infertility. We presumed that--since the smaller the uterine size at the time of myomectomy, the greater the chances of subsequent conception--diminishing the preoperative tumor size in infertile patients with large leiomyomata prior to myomectomy should be beneficial. PROCEDURE: Decapeptyl (D-Trp6-LHRH) depot 3.2 mg was administered for a period of 3-6 months to 23 infertile women. No causes of infertility were found in these patients except for uterine leiomyomata. In 10 of the 23 patients conservative myomectomy was added to Decapeptyl treatment. FINDINGS: Following Decapeptyl treatment an average decrease in uterine volume of 57% (range: 22%-86%) was observed in all patients. In ten of the 23 patients conservative myomectomy was added to Decapeptyl treatment resulting in a further 16% decrease in uterine volume. Uterine regrowth following Decapeptyl and myomectomy was found to be significantly lower (P < 0.01) when compared with cases treated with Decapeptyl alone. Five of the ten patients treated by Decapeptyl and myomectomy achieved successful pregnancies and delivered. Among the women treated with Decapeptyl without myomectomy, only one patient conceived. CONCLUSIONS: From these findings it may be concluded that combined GnRH and myomectomy is the treatment of choice for infertile women with large uterine leiomyomata.

Adult↗