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Biomedical subjects

H Abramovici

Publications and source records attributed to H Abramovici.

At least 127 records · Page 7Linked to original sources
PubMed1980

Extraovular instillations of normal saline for termination of midtrimester pregnancy.

Midtrimester abortion by extraovular instillation of normal saline was performed in 50 patients. All 50 aborted following the procedure, and there were no complications except for one case of endometritis that was successfully treated by antibiotics. The mean abortion time was 33 hours, without added oxytocin, and 30 hours when pitocin was administered intravenously. The extraovular route eliminates the necessity for amniocentesis, with its associated risks. By using normal saline instead of pharmacologic agents such as urea, glucose, hypertonic saline, prostaglandins, we were able to eliminate the complications related to drug side effects.

Abortion, Induced↗
PubMed1980

Classification of threatened premature labor related to treatment with a prostaglandin inhibitor: indomethacin.

68 patients complaining of premature uterine contractions were treated with a prostaglandin synthetase inhibitor--indomethacin. This agent had a marked effect on uterine contractions suppressing them completely after 1--8 h from the administration of the drug. Classificaiton of the premature contractions according to a scoring system method is analyzed in this study. The score classified the patients into three groups and enabled us to treat them with a correct dosage and period according to the clinical findings at admission of the patients. Indomethacin treatment was effective in all the 68 patients. The drug was well tolerated by all the patients with minimal side effects. The outcome of the newborns was satisfactory, and laboratory tests on various systems of the pregnant women and newborns were normal during and after treatment with indomethacin.

Female↗
PubMed1980

Maternal pulmonary edema occurring after therapy with ritodrine for premature uterine contractions.

Intravenous administration of beta-sympathomimetic drugs in combination with betamethasone or dexamethasone is a treatment often used for the suppression of premature uterine contractions and for the stimulations of fetal lung maturity. It has been suggested that the combination of these drugs may be responsible for maternal pulmonary edema and five such cases have been reported in the literature (1,2). We report a patient who developed pulmonary edema during ritodrine therapy. Corticosteroids were not given in this case.

Adolescent↗
PubMed1980

Congenital adrenal hyperplasia diagnosed in a middle-aged woman.

Short stature, severe hirsutism, an enlarged clitoris and lack of vaginal introitus were manifest in a 55-year-old female karyotype, male phenotype patient brough up as a female. The hormone profile suggested congenital adrenal hyperplasia due to 21-hydroxylase adrenal enzyme deficiency. Follicle-stimulating hormone and luteinizing hormone levels were 122.5 and 100.3 mIU/ml, respectively, within the normal range for a postmenopausal woman. Computerized axial tomography revealed a large cystic tumor connected to the right adrenal gland. Both the right adrenal gland and the cyst were removed. The adrenal cortex showed diffuse hyperplasia and contained a well-defined nodule. The case was interesting because we had the opportunity of examining a patient of advanced age with untreated congenital adrenal hyperplasia and because of the very rare combination of adrenogenital syndrome with nodular hyperplasia and a cystic tumor, which was most probably a degenerated adenoma.

Adrenal Glands↗
PubMed1980

Oligohydramnion, meconium and perinatal death concurrent with indomethacin treatment in human pregnancy.

Three pregnancies in which indomethacin was given for several days to arrest premature delivery ended in oligohydramnion, meconium and perinatal death. These findings, together with previous information from animal experimentation and experience in humans reported on in the literature, show that indomethacin, a prostaglandin synthetase inhibitor, may interfere with the normal uteroplacental circulation, amniotic fluid production, renal functions and neonatal cardiopulmonary adaptation. The possible hazards of indomethacin treatment during the third trimester of pregnancy are discussed.

Adult↗
PubMed1979

Serum and amniotic fluid heat labile alkaline phosphatase and aminotransferases in association with meconium stained liquor. On their origin, distribution and clinical use.

A method for detecting meconium in the amniotic fluid is described. Samples of maternal serum, cord serum and amniotic fluid were tested for alkaline phosphatase and transaminases activity in 32 healthy, term gravidas during labor in whom meconium stained amniotic fluid was found. The values obtained were compared to those of a control group consisting of 32 normal term pregnancies in whom the amniotic fluid was clear. Mean alkaline phosphatase activity was significantly higher in the study group in all three compartments - maternal, fetal and amniotic fluid. A significant and positive correlation between levels of alkaline phosphatase in the amniotic fluid and in maternal serum was found in the study group. Alkaline phosphatase value of 550 IU/L or more in maternal serum was diagnostic and levels between 350--500 IU/L were highly suggestive for the presence of menconium in the amniotic fluid. Mean levels of transaminases (SGOT and SGPT) were similar in the two groups and all were within normal range. The origin of alkaline phosphatase and the mode of transfer of the three enzymes are also discussed. It is suggested that this method can also be used during the third trimester of pregnancy.

Adult↗
PubMed1978

A simple ambulatory method for removal of occult IUDs.

With the increased popularity of the IUD as a contraceptive method, there is a rise in the cases of occult IUDs as a result of the disappearance of the threads from the vagina. Our experience has shown that in the cases where the marker is missing, but the IUD is in the uterine cavity, it can be easily removed by using the Novak curette. This procedure spares the patients general anesthesia, D & C, and unnecessary hospitalization with its expenses.

Ambulatory Care↗
PubMed1978

The correlation between sperm count and testicular biopsy using a new scoring system.

Biopsies of 320 testes were evaluated and a new scoring system for describing testicular biopsies was used. This scoring system uses four criteria in the evaluation of the biopsy: the diameter of the tubules (D), the thickness of the peritubular membrane (M), the population of cells within the tubules (P), and the spermatogenic maturation degree (S). The score of each biopsy was correlated to the sperm count of each patient. A typical correlation between the biopsy score and the sperm count was found in cases with sperm count between 0 and 12 million/cc. The clinical value of the new scoring system in describing typical clinical syndromes and in the evaluation of the prognosis of treatment was emphasized.

Adult↗
PubMed1978

The effect of postural changes on plasma renin activity during normal and pathologic pregnancies.

A study of the effect of posture on plasma renin activity (PRA) in the third trimester in 27 gravidas revealed a significantly greater increase in PRA in the supine position, compared to the left lateral. The women were classified into 3 groups: normal pregnancy, preeclampsia, intrauterine fetal death. There was no statistical difference in PRA among the 3 groups. It is assumed that the increase of PRA in the supine position was due mainly to mechanical pressure by the gravid uterus on the great vessels (regardless of whether the fetus was dead or alive) and that effective circulatory volume was thus reduced. However, low PRA in the left lateral position in women with preeclampsia seemed to correlate with more severe disease in these women.

Adult↗
PubMed1976

Electronic monitoring of the fetal heart rate and uterine contractions during cesarean section under balanced anesthesia.

The influence of balanced anesthesia (BA) on fetal heart rate (FHR) and uterine contraction (UC) patterns was evaluated in pregnant women undergoing emergency cesarean section. The results showed that during operative delivery under BA there was a significant decrease in the beat-to-beat variability of the FHR, most probably due to the anesthetic agent. There was a decrease in uterine contractility expressed by the significant decreases in the peak pressure as well as in the duration of the uterine contractions. Periodic changes in the FHR as decelerations and acclerations disappeared or improved mostly due to the decrease of uterine contractility.

Anesthesia, Obstetrical↗