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Biomedical subjects

H Aberg

Publications and source records attributed to H Aberg.

At least 145 records · Page 8Linked to original sources
PubMed1975

Controlled study of atenolol in treatment of hypertension.

The antihypertensive effect of atenolol, a new beta-1-receptor blocking agent, was studied in a double-blind trial in which 45 patients with essential hypertension were randomly assigned to placebo or atenolol treatment. Atenolol caused a statistically significant and clinically relevant reduction of blood pressure. The optimum daily dose for moderately severe hypertension was considered to be 200 mg. Several irrelevant side effects were collected by the use of a check list, but there was no difference in the number of complaints during placebo and active treatment. Atenolol has a useful antihypertensive effect and, at least theoretically, has advantages over other beta-adrenergic blocking agents.

Adolescent↗
PubMed1975

A 3-year follow-up of middle-aged men with borderline blood pressure.

Ninety-eight middle-aged men with untreated borderline raised blood pressure (BP) have been reexamined after three years. Twenty-five subjects were considered to be hypertensive, motivating a shorter interval for rescreening. Systolic BP had decreased in 23%, diastolic BP in 46% and both pressures in 15%. Those who developed hypertension had higher systolic BP at the initial examination. A family history of hypertension was more common in this group.

Blood Pressure↗
PubMed1975

Atrial activity during exercise in patients with atrial flutter or atrial fibrillation.

The atrial activity was studied at rest and during exercise in 6 patients with atrial flutter and in 7 patients with atrial fibrillation. In the latter, a special recording technique was used which permitted identification of the f-waves. No increase in the frequency of the atrial waves was found. Thus the increase of the ventricular rate during work in patients with atrial flutter or atrial fibrillation seems to be caused by a change in the atrio-ventricular conduction.

Adult↗
PubMed1975

Dopamine-beta-hydroxylase and plasma renin activity in twenty hypertensive subjects.

Dopamine-beta-hydroxylase (DBH), the enzyme responsible for the biosynthesis of noradrenalin from dopamine, was assayed in the blood plasma of 20 men with primary hypertension. At the same time plasma was taken for measurement of plasma renin activity. Renin release as well as the plasma level of DBH is dependent upon the activity of the sympathetic nervous system, at least to some extent. A possible relationship between the two enzymes was therefore investigated. However, no relationship could be found in this series of 20 hypertensive patients. Another aim was to study the levels of DBH in venous and arterial blood simultaneously. No difference in the DBH level was found in venous and in arterial blood in 11 patients undergoing heart catheterization.

Adult↗
PubMed1975

Dopamine-beta-hydroxylase after treatment with beta-blockers in hypertension.

Dopamine-beta-hydroxylase (DBH) the enzyme responsible for the biosynthesis of noradrenaline from dopamine, was assayed in the blood plasma of 19 cases with hypertension before and during beta-receptor blockade. Propranolol was given to 15 patients and I.C.I. 66,082 (a new cardioselective beta-adrenergic blocker without intrinsic sympathomimetic properties) to 4 patients. - There was no effect by the drugs on the level of plasma DBH activity in spite of a good reduction of the blood pressure.

Atenolol↗