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Biomedical subjects

H Aberg

Publications and source records attributed to H Aberg.

At least 109 records · Page 6Linked to original sources
PubMed1979

Rheumatoid arthritis, immune complex disease, and hypereosinophilic syndrome. Report on a case.

A patient with typical rheumatoid arthritis is presented. After a short period of the disease a hyperosinophilic syndrome (HES) developed with vasculitis, pulmonary fibrosis, and thrombosis, and the disease took a malignant course. The patient died within a year after the diagnosis of HES. High titres of rheumatoid factor were manifested and total complement (CH50) was very low, indicating an active immune disease. As HES has been suggested to have an autoimmune aetiology, these findings are interesting, as positive rheumatoid serology has very rarely been reported in patients with this syndrome.

Arthritis, Rheumatoid↗
PubMed1979

Blood pressure in 60-year-old men. Findings in a health survey and some comparisons with 50-year-old men in the same community.

A population survey of 60-year-old men (n=331) was performed in Uppsala. tthe prevalence of hypertension defined as established hypertension and those having an unknown diastolic blood pressure (DBP) of greater than or equal to 105 mmHg was 19.3%. Of the hypertensive population, 35.9% had not been detected previously. In the treated group, 43.9% were poorly controlled regarding the BP level. Thus 64.1% of the total hypertensive population at the age of 60 years were either undetected or inadequately controlled. Excretion of urinary electrolytes was also evaluated in this work. All participants of the health survey except four performed a 24-hour collection of urine following the health examination. Care was taken with endogenous creatinine clearance. Negative and significant correlations were noted between excretion of sodium and potassium in urine and DBP levels in the group (n=23) of untreated hypertensives. In a population sample (n=135) of healthy subjects devoid of medical treatment in the same population survey, a positive and significant correlation was noted between the systolic BP and the urinary excretion of sodium. Thus up to a certain BP level there is a pressure diuresis and at higher BP levels the kidney retains electrolytes.

Blood Pressure↗
PubMed1978

Renal haemodynamics before and after splanchnic block in patients with hypertension.

In eighteen patients with hypertension of presumed renal origin the haemodynamics of the kidney were studied by arterial pressure recording, blood flow measurement and selective arteriography before and after a splanchnic block. The material was divided into kidneys with and kidneys without arterial stenosis. In these patients with hypertension a positive correlation was found between mean arterial pressure and renal vascular resistance both before and after the splanchnic block. In patients with renal arterial stenosis the change in relative renal vascular resistance was negatively correlated to the initial resistance, implying that in kidneys with a high initial vascular resistance the resistance decreased to a relatively greater extent than in kidneys with a low initial resistance. At high blood pressures ischaemic areas in the kidney were found. The volume of these areas is dependent upon sympathetic tone, such that a high sympathetic tone results in ischaemia of a larger volume of the kidney. This applies both to kidneys with and to those without arterial stenosis. The results of this investigation thus support the assumption that in the presence of hypertension a kidney is under the control of a sympathetic tone that may form a part of the pathogenetic process in hypertension.

Adult↗
PubMed1978

Studies on toxemia of pregnancy with special reference to blood pressure. I. Incidence and some characteristic features of the mothers and infants.

An investigation was made of 150 women who were diagnosed at the Department of Obstetrics and Gynaecology, University Hospital, Uppsala in 1964-68 as having toxaemia of pregnancy. Eleven had eclampsia and the remainder pre-eclampsia. Toxaemia occurred in 0.88% (average) of all parturients during the study period. Some characteristics of the mothers and their infants are reported. Thus, there were more instrumental deliveries in the toxaemia group than in the non-toxaemic patients delivered in the clinic. The maternal weight at delivery was also greater in the toxaemia group. The frequency of complications among the infants was higher in the group with toxaemia. There were more stillbirths, lower birth weights and more congenital malformations. With regard to blood pressure, almost identical pressures were noted in the eclamptic and pre-eclamptic groups, with one exception. The maximum blood pressure recorded during delivery was higher in the eclamptic than in the pre-eclamptic group (198/127 and 175/117).

Birth Weight↗
PubMed1978

Studies on toxaemia of pregnancy with special reference to blood pressure. II. Results after 6-11 years' follow-up.

One hundred and fifty women with a diagnosis of toxaemia of pregnancy treated in the Department of Obstetrics and Gynaecology, University Hospital, Uppsala between 1964 and 1968 were investigated. One hundred women were still living in the area in 1975 and thus could be restudied. The participation rate was 100% in this group. After this follow-up period of 6-11 years 17 women were hypertensives at the investigation and 12 were already on antihypertensive therapy. The incidence of hypertension was thus 29%. The toxaemic women who had developed gypertension showed a higher frequency of a family history of hypertension as well as of cardiovascular lesions than the toxaemic women with normal blood pressures at follow-up. At the time of the toxaemia the future hypertensive women (n=29) had a higher blood pressure on admission, as well as a greater body weight, than the women who were normotensive at the follow-up investigation. Forty-six of the 100 re-studied women were taking contraceptive pills. Seven developed hypertension while 'on the pill'. Four of these became normotensive after discontinuating the pill.

Blood Pressure↗
PubMed1978

Abdominal aortic aneurysm in homocystinuria.

The first reported case of abdominal aortic aneurysm complicating homocystinuria is presented. The clinical features and microscopic findings were identical to those of an atherosclerotic aneurysm. Homocystinuria may stimulate Marfan's syndrome but can be differentiated by the cyanide-nitroprusside screening test for homocystine in urine. Although homocystinuria is accompanied by an increased risk of thrombosis, surgical treatment of complicating diseases should not be avoided. Pyridoxine treatment is recommended.

Adult↗
PubMed1977

Arterial segmental vasoconstriction. Frequency and pathogenetic factors.

Frequency and pathogenetic factors involved in arterial segmental vasoconstriction observed in a series of 55 patients are analyzed. A large number presented peripheral nutritional disturbance and these included 5 patients with definite or highly possible Buerger's disease. The possibility that in certain patients segmental vasoconstriction may be an early sign of systemic or local arterial disease is discussed.

Adolescent↗