Search PubMed⌕ Search

Biomedical subjects

H A Tran

Publications and source records attributed to H A Tran.

8 recordsLinked to original sources

Extreme hyperkalemia.

Hyperkalemia is a potentially fatal condition and is defined by a serum potassium level (K+) of greater than 5.5 mmol/L. The associated prevalence of cardiac arrhythmia increases directly with the degree of hyperkalemia. The danger in the majority of hyperkalemia cases is cardiac dysrhythmia, and often ventricular fibrillation or asystole is the terminating event. Although there are many previous reports addressing this threatening problem and associated therapeutic maneuvers, there have not been many previous reports citing the fatal concentration of hyperkalemia irrespective of the causes. However, it is uniformly accepted that a K+ concentration greater than 10.0 mmol/L is fatal unless urgent treatment is instituted. This report describes a case of nonfatal hyperkalemia of 14 mmol/L with intact survival and complete recovery. Potassium homeostasis is revisited, and some explanations are proffered regarding the protective mechanism against hyperkalemia, including transcellular flux, renal tubular function, and endocrine responses.

Cardiopulmonary Resuscitation↗

Thyrotoxic, hypokalaemic periodic paralysis in Australasian men.

Abstract The present study describes the clinical and laboratory features of 11 patients with thyrotoxic, hypokalaemic periodic paralysis, presenting to five Melbourne teaching hospitals between 1991 and 2000. All 11 patients were Asian or Polynesian men aged 18-41 years, and most had experienced previous episodes of acute, unexplained paralysis. All cases resolved without significant morbidity. Thyrotoxic, hypokalaemic periodic paralysis is a potentially life-threatening and terrifying condition, which is often under-recognized and will present with increasing frequency in the community. The diagnosis should be considered in any Asian-Australian male presenting with sudden onset paralysis.

Adolescent↗

Pregnancy-associated osteoporosis with hypercalcaemia.

Pregnancy-associated osteoporosis is an uncommon condition. It predominantly affects thinly built, primigravid, lactating women. These patients can sustain vertebral fractures with minimal or no trauma, resulting in significant morbidity. The association with hypercalcaemia is rare and typically occurs during the first few months postpartum, while lactating. This condition is, however, relatively benign and patients can expect to return to normal bone mineral density 6-12 months after breast-feeding has stopped.

Adult↗