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Biomedical subjects

Guoan Li

Publications and source records attributed to Guoan Li.

At least 37 records · Page 2Linked to original sources

The change in length of the medial and lateral collateral ligaments during in vivo knee flexion.

The collateral ligaments of the knee are important in maintaining knee stability. However, little data has been reported on the in vivo function of the collateral ligaments. The objective of this study was to investigate the change in length of different fiber bundles of the medial collateral ligament (MCL), deep fibers of the MCL (DMCL) and the lateral collateral ligament (LCL) during in vivo knee flexion. The knees of five healthy subjects were scanned using magnetic resonance imaging. These images were used to create three-dimensional models of the tibia and femur, including the insertions of the collateral ligaments. The MCL, DMCL, and LCL were each divided into three equal portions: an anterior bundle, a middle bundle and a posterior bundle. Next, the subjects were imaged from two orthogonal directions using fluoroscopy while performing a quasi-static lunge for 0 degree to 90 degrees of flexion. The models and fluoroscopic images were then used to reproduce the in vivo motion of the knee. From these models, the length of each bundle of each ligament was measured as a function of flexion. The length of the anterior bundle of the MCL did not change significantly with flexion. The length of the posterior bundle of the MCL consistently decreased with flexion (p less than 0.05). The changes in deformation of the DMCL and LCL as a function of flexion were similar to each other. The length of the anterior bundles increased with flexion and the length of the posterior bundles decreased with flexion. These data indicate that the collateral ligaments do not elongate uniformly as the knee is flexed, with different bundles becoming taut and slack. These data may help to provide a better understanding of the in vivo function of the collateral ligaments and be used to improve surgical reconstruction of the collateral ligaments. Furthermore, the data suggest that the different roles of various portions of the collateral ligaments along the flexion path should be considered before releasing the collateral ligaments during knee arthroplasty.

Adult↗

In vivo kinematics of the ACL during weight-bearing knee flexion.

No study has investigated the three-dimensional morphological changes of the anterior cruciate ligament (ACL) during functional activities in vivo. The purpose of this study was to analyze the elongation, rotation (twist), and orientation of the ACL during weight-bearing flexion in five human subjects using dual-orthogonal fluoroscopic images and MR image-based computer models. The ACL consistently decreased in length with flexion. At 90 degrees , the length decreased by 10% compared to its length at full extension. The ACL twisted internally by only 20 degrees at 30 degrees of flexion. The ACL was oriented more vertically (approximately 60 degrees ) and slightly laterally (approximately 10 degrees ) at low flexion angles. These data on in vivo ligament elongation demonstrate that the ACL plays a more important role in lower flexion angles than at higher flexion angles during weight-bearing flexion. These data also suggest that successful ACL reconstruction should not only restore the ligament's elongation behavior, but also its rotational and orientation characteristics, so that normal ACL biomechanics are restored.

Adult↗

Anterior tibial post impingement in a posterior stabilized total knee arthroplasty.

Despite the numerous long-term success reports of posterior stabilized (PS) total knee arthroplasty (TKA), recent retrieval studies of various PS TKA designs revealed wear and deformation on the anterior side of the tibial post. This study investigated the mechanisms of anterior impingement of the post with the femoral component. Seven cadaveric knees were tested to study kinematics and tibial post biomechanics during simulated heel strike using an in vitro robotic testing system. Intact knee kinematics and in situ anterior cruciate ligament (ACL) forces were determined at hyperextension (0 degree to -9 degrees) and low flexion angles (0 degrees to 30 degrees) under the applied loads. The same knee was reconstructed using a PS TKA. The kinematics and the tibial post contact forces of the TKA were measured under the same loading condition. The ACL in the intact knee carried load and contributed to knee stability at low flexion angles and hyperextension. After TKA, substantial in situ contact forces (252.4 +/- 173 N at 9 degrees of hyperextension) occurred in the tibial post, indicating anterior impingement with the femoral component. Consequently, the TKA showed less posterior femoral translation compared to the intact knee after the impingement. At 9 degrees of hyperextension, the medial condyle of the intact knee translated 0.1 +/- 1.1 mm whereas the medial condyle of the TKA knee translated 5.6 +/- 6.9 mm anteriorly. The lateral condyle of the intact knee translated 1.5 +/- 1.0 mm anteriorly whereas the lateral condyle of the TKA knee translated 2.1 +/- 5.8 mm anteriorly. The data demonstrated that anterior tibial post impingement functions as a substitute for the ACL during hyperextension, contributing to anterior stability. However, anterior post impingement may result in additional polyethylene wear and tibial post failure. Transmitted impingement forces might cause backside wear and component loosening. Understanding the advantages and disadvantages of the tibial post function at low flexion angles may help to further improve component design and surgical techniques and thus enhance knee stability and component longevity after TKA.

Aged↗

In vivo articular cartilage contact kinematics of the knee: an investigation using dual-orthogonal fluoroscopy and magnetic resonance image-based computer models.

BACKGROUND: Quantifying the in vivo cartilage contact mechanics of the knee may improve our understanding of the mechanisms of joint degeneration and may therefore improve the surgical repair of the joint after injury. OBJECTIVE: To measure tibiofemoral articular cartilage contact kinematics during in vivo knee flexion. STUDY DESIGN: Descriptive laboratory study. METHODS: Orthogonal fluoroscopic images and magnetic resonance image-based computer models were used to measure the motion of the cartilage contact points during a quasi-static lunge in 5 human subjects. RESULTS: On the tibial plateau, the contact point moved in both the anteroposterior and the mediolateral directions during knee flexion. On the medial tibial plateau, flexion angle did not have a statistically significant effect on the location of the contact points. The total translation of the contact point from full extension to 90 degrees of flexion was less than 1.5 mm in the anteroposterior direction, whereas the translation in the mediolateral direction was more than 5.0 mm. In the anteroposterior direction, the contact points were centered on the medial tibial plateau. On the lateral tibial plateau, there was a statistically significant difference between the location of the contact point at full extension and the locations of the contact points at other flexion angles in the anteroposterior direction. No significant difference was detected between the location of the contact points at other flexion angles. The overall range of contact point motion was about 9.0 mm in the anteroposterior direction and about 4.0 mm in the mediolateral direction. The contact points were primarily on the inner half of the medial and lateral tibial plateaus (the half closest to the tibial spine). The contact points on both femoral condyles were also on the inner half of the condyles (near the condylar notch). CONCLUSIONS: The tibiofemoral contact points move in 3 dimensions during weightbearing knee flexion. The medial tibiofemoral contact points remained within the central portion of the tibial plateau in the anteroposterior direction. Both the medial and lateral tibiofemoral contact points were located on the inner portions of the tibial plateau and femoral condyles (close to the tibial spine), indicating that the tibial spine may play an important role in knee stability. CLINICAL RELEVANCE: The results of this study may provide important insight as to the mechanisms contributing to the development of osteoarthritis after ligament injuries.

Adult↗

The effect of anterior cruciate ligament reconstruction on knee joint kinematics under simulated muscle loads.

BACKGROUND: Numerous studies have investigated anterior stability of the knee during the anterior drawer test after anterior cruciate ligament reconstruction. Few studies have evaluated anterior cruciate ligament reconstruction under physiological loads. PURPOSE: To determine whether anterior cruciate ligament reconstruction reproduced knee motion under simulated muscle loads. STUDY DESIGN: Controlled laboratory study. METHODS: Eight human cadaveric knees were tested with the anterior cruciate ligament intact, transected, and reconstructed (using a bone-patellar tendon-bone graft) on a robotic testing system. Tibial translation and rotation were measured at 0 degrees, 15 degrees, 30 degrees, 60 degrees, and 90 degrees of flexion under anterior drawer loading (130 N), quadriceps muscle loading (400 N), and combined quadriceps and hamstring muscle loading (400 N and 200 N, respectively). Repeated-measures analysis of variance and the Student-Newman-Keuls test were used to detect statistically significant differences between knee states. RESULTS: Anterior cruciate ligament reconstruction resulted in a clinically satisfactory anterior tibial translation. The anterior tibial translation of the reconstructed knee was 1.93 mm larger than the intact knee at 30 degrees of flexion under anterior load. Anterior cruciate ligament reconstruction overconstrained tibial rotation, causing significantly less internal tibial rotation in the reconstructed knee at low flexion angles (0 degrees-30 degrees) under muscle loads (P < .05). At 30 degrees of flexion, under muscle loads, the tibia of the reconstructed knee was 1.9 degrees externally rotated compared to the intact knee. CONCLUSIONS: Anterior cruciate ligament reconstruction may not restore the rotational kinematics of the intact knee under muscle loads, even though anterior tibial translation was restored to a clinically satisfactory level under anterior drawer loads. These data suggest that reproducing anterior stability under anterior tibial loads may not ensure that knee joint kinematics is restored under physiological loading conditions. CLINICAL RELEVANCE: Decreased internal rotation of the knee after anterior cruciate ligament reconstruction may lead to increased patellofemoral joint contact pressures. Future anterior cruciate ligament reconstruction techniques should aim at restoring 3-dimensional knee kinematics under physiological loads.

Anterior Cruciate Ligament↗

In vivo elongation of the anterior cruciate ligament and posterior cruciate ligament during knee flexion.

BACKGROUND: Most knowledge regarding cruciate ligament function is based on in vitro experiments. PURPOSE: To investigate the in vivo elongation of the functional bundles of the anterior cruciate ligament and posterior cruciate ligament during weightbearing flexion. HYPOTHESIS: The biomechanical role of functional bundles of the anterior cruciate ligament and posterior cruciate ligament under in vivo loading is different from that measured in cadavers. STUDY DESIGN: In vivo biomechanical study. METHODS: Elongation of the anterior cruciate ligament and posterior cruciate ligament was measured during a quasi-static lunge using imaging and 3-dimensional computer-modeling techniques. RESULTS: The anterior-medial bundle of the anterior cruciate ligament had a relatively constant length from full extension to 90 degrees of flexion. The posterior-lateral bundle of the anterior cruciate ligament decreased in length with flexion. Both bundles of the posterior cruciate ligament had increased lengths with flexion. CONCLUSION: The data did not demonstrate the reciprocal function of the 2 bundles of the anterior cruciate ligament or the posterior cruciate ligament with flexion observed in previous studies. Instead, the data suggest that there is a reciprocal function between the anterior cruciate ligament and posterior cruciate ligament with flexion. The anterior cruciate ligament plays a more important role in low-flexion angles, whereas the posterior cruciate ligament plays a more important role in high flexion. CLINICAL RELEVANCE: Understanding the biomechanical role of the knee ligaments in vivo is essential to reproduce the structural behavior of the ligament after injury (especially for 2-bundle reconstructions) and thus improve surgical outcomes.

Adult↗

The effect of posterior knee capsulotomy on posterior tibial translation during posterior cruciate ligament tibial inlay reconstruction.

PURPOSE: To measure the biomechanical effect of the surgical capsulotomy made during a posterior cruciate ligament reconstruction using the tibial inlay technique. HYPOTHESIS: The posterior capsule contributes to posterior tibial stability. STUDY DESIGN: Controlled laboratory experiment. METHODS: Six knee specimens were tested on a robotic testing system from 0 degrees to 120 degrees of flexion with the posterior cruciate ligament intact and resected and with a posterior capsulotomy identical to that performed during tibial inlay reconstruction (sham surgery). A longitudinal incision with medial and lateral soft tissue stripping sufficient to mount an inlay bone block and pass an Achilles tendon graft into the knee was made in the oblique popliteal ligament, muscle belly of the popliteus, and posterior capsule. The posterior tibial translation was measured under a posterior tibial load of 130 N at multiple flexion angles. RESULTS: Capsulotomy increased the posterior laxity compared with the posterior cruciate ligament-resected knee at every flexion angle. An additional 0.97 +/- 0.48 mm, 0.65 +/- 0.47 mm, 0.56 +/- 0.33 mm, 0.48 +/- 0.38 mm, and 0.94 +/- 0.60 mm of posterior laxity was recorded at 0 degrees, 30 degrees, 60 degrees, 90 degrees, and 120 degrees of flexion, respectively. These values were all statistically significant (P < .001). CONCLUSIONS: A posterior capsulotomy alone, without associated posteromedial or posterolateral disruption, produces additional posterior tibial translation in vitro compared with posterior cruciate ligament-deficient knee with intact capsule. CLINICAL RELEVANCE: Damage to the posterior capsule may contribute to the residual posterior laxity noted clinically after posterior cruciate ligament reconstruction.

Achilles Tendon↗

Function of the anterior cruciate ligament after unicompartmental knee arthroplasty: an in vitro robotic study.

The objective of this study was to investigate the role of the anterior cruciate ligament (ACL) in the anterior-posterior (AP) stability of the knee after unicompartmental knee arthroplasty (UKA). AP tibial loads were applied to human cadaveric knee specimens using a robotic testing system. After UKA, the knee exhibited tibial translations similar to that of the native knee, and the forces in the ACL were also similar to those seen in the native knee. The ACL-deficient knee after UKA exhibited significantly greater anterior tibial translations than the native knee and the knee after UKA with an intact ACL. These data suggest that medial UKA does not alter the anterior stability of the knee, but a functional ACL is necessary to ensure normal stability after UKA.

Aged↗

In vivo tibiofemoral contact analysis using 3D MRI-based knee models.

This paper quantified the motion of the tibiofemoral contact points during in vivo weight bearing flexion using MRI- based 3D knee models and two orthogonal fluoroscopic images. The contact points on the medial and lateral tibial plateau were calculated by finding the centroid of the intersection of the tibial and femoral cartilage layers and by using the bony geometry alone. Our results indicate that the medial femoral condyle remains in the central portion of the tibial plateau and the lateral condyle translates posteriorly with increasing flexion. Using the bony contact model increased the total translation of the medial and lateral condyles by 250 and 55%, respectively, compared to the cartilage contact model. These results suggest that using the bony geometry alone may not accurately represent the articular surfaces of the knee. Articular cartilage geometry may have to be used to accurately quantify tibiofemoral contact.

Adult↗

Kinematics of the knee at high flexion angles: an in vitro investigation.

Restoration of knee function after total knee, meniscus, or cruciate ligament surgery requires an understanding of knee behavior throughout the entire range of knee motion. However, little data are available regarding knee kinematics and kinetics at flexion angles greater than 120 degrees (high flexion). In this study, 13 cadaveric human knee specimens were tested using an in vitro robotic experimental setup. Tibial anteroposterior translation and internal-external rotation were measured along the passive path and under simulated muscle loading from full extension to 150 degrees of flexion. Anterior tibial translation was observed in the unloaded passive path throughout, with a peak of 31.2+/-13.2 mm at 150 degrees. Internal tibial rotation increased with flexion to 150 degrees on the passive path to a maximum of 11.1+/-6.7 degrees. The simulated muscle loads affected tibial translation and rotation between full extension and 120 degrees of knee flexion. Interestingly, at high flexion, the application of muscle loads had little effect on tibial translation and rotation when compared to values at 120 degrees. The kinematic behavior of the knee at 150 degrees was markedly different from that measured at other flexion angles. Muscle loads appear to play a minimal role in influencing tibial translation and rotation at maximal flexion. The results imply that the knee is highly constrained at high flexion, which could be due in part to compression of the posterior soft tissues (posterior capsule, menisci, muscle, fat, and skin) between the tibia and the femur.

Biomechanical Phenomena↗

In situ forces of the anterior and posterior cruciate ligaments in high knee flexion: an in vitro investigation.

The function of the anterior and posterior cruciate ligaments (ACL and PCL) in the first 120 degrees of flexion has been reported extensively, but little is known of their behavior at higher flexion angles. The aim of this investigation was to study the effects of muscle loads on the in situ forces in both ligaments at high knee flexion (>120 degrees). Eighteen fresh-frozen human knee specimens were tested on a robotic testing system from full extension to 150 degrees of flexion in response to quadriceps (400 N), hamstrings (200 N), and combined quadriceps and hamstrings (400 N/200 N) loads. The in situ forces in the ACL and PCL were measured using the principle of superposition. The force in the ACL peaked at 30 degrees of flexion (71.7 +/- 27.9 N in response to the quadriceps load, 52.3 +/- 24.4 N in response to the combined muscle load, 32.3 +/- 20.9 N in response to the hamstrings load). At 150 degrees, the ACL force was approximately 30 N in response to the quadriceps load and 20 N in response to the combined muscle load and isolated hamstring load. The PCL force peaked at 90 degrees (34.0 +/- 15.3 N in response to the quadriceps load, 88.6 +/- 23.7 N in response to the combined muscle load, 99.8 +/- 24.0 N in response to the hamstrings load) and decreased to around 35 N at 150 degrees in response to each of the loads. These results demonstrate that the ACL and PCL carried significantly less load at high flexion in response to the simulated muscle loads compared to the peak loads they carried in response to the same muscle loads at other flexion angles. The data could provide a reference point for the investigation of non-weight bearing flexion and extension knee exercises in high flexion. Furthermore, these data could be useful in designing total knee implants to achieve high flexion.

Aged↗

Feasibility of using orthogonal fluoroscopic images to measure in vivo joint kinematics.

Accurately determining in vivo knee kinematics is still a challenge in biomedical engineering. This paper presents an imaging technique using two orthogonal images to measure 6 degree-of-freedom (DOF) knee kinematics during weight-bearing flexion. Using this technique, orthogonal images of the knee were captured using a 3-D fluoroscope at different flexion angles during weight-bearing flexion. The two orthogonal images uniquely characterized the knee position at the specific flexion angle. A virtual fluoroscope was then created in solid modeling software and was used to reproduce the relative positions of the orthogonal images and X-ray sources of the 3-D fluoroscope during the actual imaging procedure. Two virtual cameras in the software were used to represent the X-ray sources. The 3-D computer model of the knee was then introduced into the virtual fluoroscope and was projected onto the orthogonal images by the two virtual cameras. By matching the projections of the knee model to the orthogonal images of the knee obtained during weight-bearing flexion, the knee kinematics in 6 DOF were determined. Using regularly shaped objects with known positions and orientations, this technique was shown to have an accuracy of 0.1 mm and 0.1 deg in determining the positions and orientations of the objects, respectively.

Adult↗

The effect of length on the structural properties of an Achilles tendon graft as used in posterior cruciate ligament reconstruction.

BACKGROUND: The clinical outcomes of posterior cruciate ligament reconstruction are varied. No previous studies have investigated the effect of graft length on the structural properties of the graft. HYPOTHESIS: Graft length significantly affects the structural properties of posterior cruciate ligament grafts. STUDY DESIGN: Controlled laboratory study. METHODS: Eight Achilles tendon grafts were tested under tensile loads up to 400 N at 3 different lengths: long (75 mm), medium (48 mm), and short (34 mm). These 3 lengths represent midtunnel fixation, inlay fixation, and fixation near the ligament insertions. RESULTS: Shortening the graft from both long to medium and from medium to short increased the stiffness by approximately 25%. Long and medium grafts displaced significantly more than medium and short grafts, respectively. CONCLUSION: The effective length of a graft, which is determined by where it is fixed, should be considered an important variable in posterior cruciate ligament reconstruction.

Achilles Tendon↗

In vivo function of the posterior cruciate ligament during weightbearing knee flexion.

BACKGROUND: Current knowledge of posterior cruciate ligament function is mainly based on in vitro cadaveric studies. There are few studies on the in vivo function of the posterior cruciate ligament. The objective of the study was to quantify the multidimensional deformation of the posterior cruciate ligament. HYPOTHESIS: During in vivo weightbearing flexion, the posterior cruciate ligament undergoes complex 3-dimensional deformations, including elongation, twist, and changes in orientation. STUDY DESIGN: In vivo biomechanical study. METHODS: Magnetic resonance images of 5 human knees were used to create 3-dimensional computer models of each subject's knee, including the insertion areas of the posterior cruciate ligament. Orthogonal fluoroscopic images of each subject's knee were acquired as a quasi-static lunge was performed. The images and computer models were used to reproduce the in vivo motion of the knee. The relative motion of the femoral and tibial insertions was described in terms of elongation, twist, elevation (the angle between the tibial plateau and posterior cruciate ligament, measured in the sagittal plane), and deviation (mediolateral orientation, measured in plane of tibial plateau). RESULTS: The length of the posterior cruciate ligament increased significantly with increasing flexion. It twisted almost 80 degrees as the knee flexed from 0 degrees to 90 degrees . The elevation angle remained relatively constant at 50 degrees . The deviation angle was medially oriented by 20 degrees at full extension, then decreased to approximately 10 degrees at 30 degrees through 90 degrees of flexion. CONCLUSION: The posterior cruciate ligament undergoes a complex twisting motion as it elongates with flexion. CLINICAL RELEVANCE: During reconstruction, the tunnels and graft may need to be placed such that the multidimensional deformation of the intact posterior cruciate ligament is reproduced.

Adult↗

Knee kinematics with a high-flexion posterior stabilized total knee prosthesis: an in vitro robotic experimental investigation.

BACKGROUND: An analysis of contemporary total knee arthroplasty reveals that, on the average, patients rarely flex the knee beyond 120 degrees. The biomechanical mechanisms that inhibit further flexion after total knee arthroplasty are unknown. The objective of the present study was to investigate the capability of a single design of a fixed-bearing, high-flexion posterior stabilized total knee arthroplasty system (LPS-Flex) to restore the range of flexion to that of the intact knee. METHODS: Thirteen cadaveric human knees were tested, with use of a robotic testing system, before and after total knee arthroplasty with the LPS-Flex prosthesis. The passive path and the kinematics under an isolated quadriceps force of 400 N, under an isolated hamstring force of 200 N, and with these forces combined were determined. Posterior femoral translation of the lateral and medial femoral condyles and tibial rotation were recorded from 0 degrees to 150 degrees of flexion. RESULTS: The medial and lateral condyles of the intact knee translated posteriorly from full extension to 150 degrees, reaching a mean peak (and standard deviation) of 22.9 +/- 11.3 mm and 31.9 +/- 12.5 mm, respectively, under the combined muscle forces. Following total knee arthroplasty, the amount of posterior femoral translation was lower than that observed in the intact knee. At 150 degrees, approximately 90% of the intact posterior femoral translation was recovered by the total knee replacement. Internal tibial rotation was observed for all knees throughout the range of motion. The cam-spine mechanism engaged at approximately 80 degrees and disengaged at 135 degrees. Despite the absence of cam-spine engagement, further posterior femoral translation occurred from 135 degrees to 150 degrees. CONCLUSIONS: The tibiofemoral articular geometry of the intact knee and the knee after total knee arthroplasty with use of the LPS-Flex design demonstrated similar kinematics at high flexion angles. The cam-spine mechanism enhanced posterior femoral translation only at the mid-range of flexion. The femoral component geometry of the LPS-Flex total knee prosthesis may improve posterior tibiofemoral articulation contact in high flexion angles.

Aged↗

The effect of graft stiffness on knee joint biomechanics after ACL reconstruction--a 3D computational simulation.

OBJECTIVE: The objective was to determine the effect of varying graft stiffness and initial graft tension on knee kinematics and graft tension after anterior cruciate ligament reconstruction. DESIGN: A 3D computational knee model was used. BACKGROUND: Many factors influencing the biomechanical outcome of anterior cruciate ligament reconstruction have been investigated. However, there are no reports on the effect of variations in graft stiffness on knee behavior. METHODS: A 3D computational knee model was used to simulate anterior cruciate ligament reconstruction using three different grafts with stiffnesses similar to the anterior cruciate ligament (graft 1), a 10mm bone-patellar tendon-bone graft (graft 2), and a 14 mm bone-patellar tendon-bone graft (graft 3). The initial graft tension was set to 0 or 40 N with the knee at 30 degrees of flexion. A 134 N anterior tibial drawer load and a 400 N quadriceps load were applied to the knee, and kinematics and graft tension were calculated. RESULTS: When fixed with no initial tension, graft 1 was found to under-constrain the knee, while graft 2 slightly over-constrained the knee, and graft 3 over-constrained the knee when compared to the intact knee. When an initial graft tension of 40 N was used, all of the reconstructed knees were more constrained than when an initial tension of 0 N was used. CONCLUSIONS: This study suggests that graft stiffness has a direct impact on knee biomechanics after anterior cruciate ligament reconstruction. An optimal anterior cruciate ligament reconstruction can be achieved if the anterior cruciate ligament is replaced by a graft with similar structural stiffness. RELEVANCE: This study showed that if the graft material and fixation sites are selected such that the anterior cruciate ligament structural stiffness is retained, normal knee kinematics can be restored.

Aged↗

Femoral rollback after cruciate-retaining and stabilizing total knee arthroplasty.

Limited data comparing the kinematics of posterior cruciate ligament-retaining or substituting total knee arthroplasty with its own intact knee under identical loadings is available. In the current study, posterior femoral translation of the lateral and medial femoral condyles under unloaded conditions was examined for intact, cruciate-retaining, cruciate ligament-deficient cruciate-retaining and posterior-substituting knee arthroplasties. Cruciate-retaining and substituting total knee arthroplasties behaved similarly to the cruciate-deficient cruciate-retaining total knee arthroplasty between 0 degrees and 30 degrees flexion. Beyond 30 degrees, the posterior cruciate-retaining arthroplasty showed a significant increase in posterior translation of both femoral condyles. The posterior cruciate-substituting arthroplasty only showed a significant increase in posterior femoral translation after 90 degrees. At 120 degrees, both arthroplasties restored approximately 80% of that of the native knee. Posterior translation of the lateral femoral condyle was greater than that observed in the medial condyle for all knees, indicating the presence of internal tibial rotation during knee flexion. The data showed that the posterior cruciate ligament is an important structure in posterior cruciate-retaining total knee arthroplasty and proper balancing is imperative to the success of the implant. The cam-spine engagement is valuable in restoring posterior femoral translation in posterior cruciate-substituting total knee arthroplasty.

Aged↗

Optimizing flexion after total knee arthroplasty: advances in prosthetic design.

The clinical results with most modern total knee arthroplasty (TKA) designs are highly satisfactory regarding pain relief and improving walking ability. However, one problem that has not been addressed fully by most current designs is the ability to consistently achieve flexion greater than 120 degrees. Although the human knee is capable of flexion of more than 150 degrees, an analysis of the results of contemporary TKA reveals that on average, patients rarely flex beyond 120 degrees. Key factors influencing range of flexion after TKA include preoperative knee motion, surgical technique, prosthetic design, and rehabilitation. The success of any total knee system may in part be linked to its ability to optimally restore normal kinematic function. Some arthroplasty designs currently are available that incorporate modifications aimed at improving range of flexion, but limited data currently are available on their function and potential advantages. Currently, an in vitro experimental model incorporating robotics is being used to investigate the kinematics of the native knee and various TKA designs at flexion angles beyond 120 degrees. This robotic model in conjunction with clinical studies may provide an understanding of the limitations of contemporary knee designs regarding achieving higher degrees of knee flexion. This may lead to the refinement of existing designs and development of newer prostheses that may enhance the range of flexion that is achievable after TKA.

Arthroplasty, Replacement, Knee↗