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Biomedical subjects

Greg Gbur

Publications and source records attributed to Greg Gbur.

11 recordsLinked to original sources

Multispectral intensity diffraction tomography reconstruction theory: quasi-nondispersive objects.

A multispectral intensity diffraction tomography (I-DT) reconstruction theory for quasi-nondispersive scattering objects is developed and investigated. By "quasi-nondispersive" we refer to an object that is characterized by a refractive index distribution that is approximately nondispersive over a predefined finite temporal frequency interval in which the tomographic measurements are acquired. The scanning requirements and measurement data are shown to be different than in conventional I-DT. Unlike conventional I-DT that requires intensity measurements on a pair of detector planes for each probing wave field, this new method uses measurements on a single detector plane at two frequencies. Computer simulation studies are conducted to demonstrate the method.

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Spherical-wave intensity diffraction tomography.

An extension of the recently developed method of intensity diffraction tomography is derived that assumes that the probing field is a spherical wave produced by a point source sufficiently far from the scatterer. A discussion of the method and numerical reconstructions of a simulated three-dimensional scattering object are presented.

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Image reconstruction in spherical-wave intensity diffraction tomography.

A reconstruction theory for intensity diffraction tomography (I-DT) has been proposed that permits reconstruction of a weakly scattering object without explicit knowledge of phase information. We investigate the I-DT reconstruction problem assuming an incident (paraxial) spherical wave and scanning geometries that employ fixed source-to-object distances. Novel reconstruction methods are derived by identifying and exploiting tomographic symmetries and the rotational invariance of the problem. An underlying theme is that symmetries in tomographic imaging systems can facilitate solutions for phase-retrieval problems. A preliminary numerical investigation of the developed reconstruction methods is presented.

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Connection between phase singularities and the radiation pattern of a slit in a metal plate.

We report a new fundamental relation between the minima of the far-zone radiation pattern of a narrow slit in a metal plate and the location of phase singularities in the intermediate field. If a system parameter such as the wavelength is changed, a previously unappreciated singular optics phenomenon occurs: namely, the transition of a near-zone phase singularity into a singularity of the radiation pattern. Our results have significance for the design of novel nanoscale light sources and antennas.

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Half-scan and single-plane intensity diffraction tomography for phase objects.

A reconstruction theory for intensity diffraction tomography (I-DT) has been proposed that permits reconstruction of a weakly scattering object without explicit knowledge of phase information. In this work, we examine the application of I-DT, using either planar- or spherical-wave incident wavefields, for imaging three-dimensional (3D) phase objects. We develop and investigate two algorithms for reconstructing phase objects that utilize only half of the measurements that would be needed to reconstruct a complex-valued object function. Each reconstruction algorithm reconstructs the phase object by use of different sets of intensity measurements. Although the developed reconstruction algorithms are equivalent mathematically, we demonstrate that their numerical and noise propagation properties differ considerably. We implement numerically the reconstruction algorithms and present reconstructed images to demonstrate their use and to corroborate our theoretical assertions.

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Coherence properties of sunlight.

The coherence properties of sunlight were first studied by Verdet around 1869 and were later examined by other scientists. However, all the previous calculations assumed that the Earth is in the far zone of the Sun, an assumption that is incorrect. An investigation of why Verdet's result is nevertheless correct reveals a surprising property of radiation from incoherent sources.

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Can spatial coherence effects produce a local minimum of intensity at focus?

It is demonstrated that, for high-Fresnel-number focusing systems illuminated by certain classes of partially coherent light, it is possible to produce a local minimum of intensity at the geometrical focus. Such an effect is possible even though the average intensity in the entrance plane of the lens is uniform. An explanation is offered for this effect, and potential applications are considered.

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Phase singularities of the coherence functions in Young's interference pattern.

We analyze the coherence properties of a partially coherent field emerging from two pinholes in an opaque screen and show that the spectral degree of coherence possesses phase singularities on certain surfaces in the region of superposition. To our knowledge, this is the first illustration of the singular behavior of the spectral degree of coherence, and the results extend the field of singular optics to the study of phase singularities of correlation functions.

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Spreading of partially coherent beams in random media.

Some published computational work has suggested that partially coherent beams may be less susceptible to distortions caused by propagation through random media than fully coherent beams. In this paper this suggestion is studied quantitatively by examining the mean squared width of partially coherent beams in such media as a function of the propagation distance. The analysis indicates under what conditions, and to what extent, partially coherent beams are less affected by the medium.

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Singular behavior of the spectrum in the neighborhood of focus.

In a recent paper [Phys. Rev. Lett. 88, 013901 (2002)] it was shown that when a convergent spatially coherent polychromatic wave is diffracted at an aperture, remarkable spectral changes take place on axis in the neighborhood of certain points near the geometrical focus. In particular, it was shown that the spectrum is red-shifted at some points, blueshifted at others, and split into two lines elsewhere. In the present paper we extend the analysis and show that similar changes take place in the focal plane, in the neighborhood of the dark rings of the Airy pattern.

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Hybrid diffraction tomography without phase information.

We introduce a hybrid tomographic method, based on recent investigations concerning the connection between computed tomography and diffraction tomography, that allows direct reconstruction of scattering objects from intensity measurements. This technique is noniterative and is intuitively easier to understand and easier to implement than some other methods described in the literature. The manner in which the new method reduces to computed tomography at short wavelengths is discussed. Numerical examples of reconstructions are presented.

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