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Biomedical subjects

Gordon D Logan

Publications and source records attributed to Gordon D Logan.

28 records · Page 2Linked to original sources

Inhibitory attentional control in patients with frontal lobe damage.

The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control-the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.

Adult↗

Selective inhibition in children with attention-deficit hyperactivity disorder off and on stimulant medication.

Selective inhibition requires discrimination between auditory signals and is assessed using a modification of the stop-signal task. Selective inhibition was assessed in a group of 59 clinic-referred, DSM-IV-diagnosed children with attention-deficit hyperactivity disorder (ADHD) and compared to that of a community sample of 59 children. Methylphenidate (MPH) effects on selective inhibition were assessed in a subset of the ADHD sample that participated in an acute, randomized, placebo-controlled, crossover trial with 3 fixed doses of MPH. Children with ADHD performed more poorly than controls on the majority of selective stop-signal task parameters: they exhibited more anticipatory (invalid) responses, with less accurate and more variable responses on the response execution task, as well as a slower selective inhibition process. MPH improved speed of both inhibition and response execution processes; it also reduced variability of response execution and decreased nonselective inhibition. On the one hand, findings are consistent with purported inhibition deficit in ADHD, but on the other hand, suggest that neither the impairment itself, nor MPH effects, were restricted to inhibition.

Attention Deficit Disorder with Hyperactivity↗

Clever homunculus: is there an endogenous act of control in the explicit task-cuing procedure?

Does the explicit task-cuing procedure require an endogenous a act of control? In 5 experiments, cues indicating which task to perform preceded targets by several stimulus onset asynchronies (SOAs). Two models were developed to account for changes in reaction time (RT) with SOA. Model 1 assumed an endogenous act of task switching for cue alterations but not for cue repetitions. Model 2 assumed no such act. In Experiments 1 and 2, the cue was masked or not masked. Masking interacted underadditively with repetition and alternation, consistent with Model 2 but not Model 1. In Experiments 3 and 4, 2 cues were used for each task. RT was slower for task repetition than for cue repetition and about the same as RT for task alternation, consistent with Model 2 but not Model 1. The results suggest that the explicit task-cuing procedure does not require an endogenous act of control.

Brain↗

Simon-type effects: chronometric evidence for keypress schemata in typewriting.

In 4 experiments, chronometric evidence for keypress schemata in typing was sought by presenting stimuli to be typed in positions that were displaced from a central fixation point. Reaction times were shorter when stimulus positions corresponded to keyboard locations of the letters to be typed, suggesting that position was an important part of the internal representation of the response. Experiment 1 presented single letters left and right of fixation. Experiment 2 presented single letters above and below fixation. Experiment 3 presented words left and right of fixation and found evidence of parallel activation of keypress schemata. Experiment 4 found no effect of the eccentricity of the keyboard locations and responding fingers, suggesting that response-location codes are categorical, not metric. The results are consistent with D. E. Rumelhart and D. A. Norman's (1982) theory of typewriting.

Adult↗

Repetition priming mediated by task similarity in semantic classification.

In the present study, the specificity of repetition priming between semantic classification tasks was examined using Osgood's (Osgood, Suci, & Tannenbaum, 1957) semantic space as a heuristic for determining the similarity between classifications. The classification tasks involved judging the meaning of words on semantic scales, such as pleasant/unpleasant. The amount of priming across classifications was hypothesized to decrease with increasing distance (decreasing similarity) between semantic scales in connotative semantic space. The results showed maximum repetition priming when the study and the test classifications were the same, intermediate degrees of priming when the study and the test classification scales shared loadings on semantic factors, and little priming when the study and the test classification scales loaded primarily on orthogonal semantic factors--that is, when the distance between scales was maximized. Consistent with the transfer-appropriate processing framework, repetition priming in semantic classifications was highly task specific, decreasing with increasing distance between classification scales.

Attention↗

Subitizing and similarity: toward a pattern-matching theory of enumeration.

Pattern-matching theories of subitizing claim that subjects enumerate displays with small numerosities by retrieving numerical responses associated with similar displays experienced in the past. Such retrieval implies that displays with small numerosities are similar to other displays of the same numerosity and dissimilar to other displays of different numerosities. These hypotheses were tested by having subjects rate the similarities of displays of dot patterns with numerosities in the range of 1-10. One group of subjects rated patterns of the same numerosity. Their ratings were higher for patterns in the subitizing range (numerosities of 1-3) than for patterns beyond the subitizing range (numerosities of 4-10). Another group rated patterns of different numerosities. Their ratings were lower in the subitizing range than beyond the subitizing range. An analysis based on multidimensional scaling suggested that numerosity could be retrieved accurately for displays of 1-3 dots, but not for displays of 4-10 dots.

Humans↗

Reduced response readiness delays stop signal inhibition.

This study examines the effect of response readiness on the stopping of motor responses. Thirteen subjects performed a primary task requiring a speeded choice reaction on go trials and response inhibition on nogo trials. An occasional cue informed subjects that a nogo trial was imminent but left them uncertain about the number of go trials separating the cue and the upcoming nogo trial. This setup was meant to create test episodes of reduced response readiness (i.e., trial sequences initiated by the cue and terminated by the nogo signal) and control episodes, in which subjects were ready to execute a speeded choice reaction (i.e., trial sequences consisting only of go trials). During both episodes, a visual stop signal could occasionally and unpredictably follow go signal onset, instructing subjects to withhold their response to the go signal. Choice reactions on go trials were delayed during test episodes relative to control episodes. Most importantly, stop reactions were delayed, not facilitated, during test episodes compared to control episodes. These findings were taken to suggest that reduced readiness gives rise to more forceful responses that are then more difficult to inhibit.

Adult↗

An instance theory of attention and memory.

An instance theory of attention and memory (ITAM) is presented that integrates formal theories of attention and memory phenomena by exploiting commonalities in their formal structure. The core idea in each theory is that performance depends on a choice process that can be modeled as a race between competing alternatives. Attention and categorization are viewed as different perspectives on the same race. Attention selects objects by categorizing them; objects are categorized by attending to them. ITAM incorporates each of its ancestors as a special case, so it inherits their successes.

Attention↗

The development of selective inhibitory control across the life span.

A modification of the stop-signal task was used to investigate the development of selective inhibitory control. A group of 317 participants, age 6 to 82 years, performed a visual choice reaction time (go) task and attempted to selectively inhibit their response to the go task when hearing one of two randomly presented tones (1000 Hz, 250 Hz), each presented on 20% of trials. Measures of response execution and inhibition were assessed by using reaction times to the go signal (GoRT) and stop signal (SSRT), respectively. Results indicated that SSRT gets faster with increasing age throughout childhood, with pronounced slowing in older adulthood. In addition, strong evidence was obtained for age-related speeding in GoRT throughout childhood, with marked slowing throughout adulthood. Subsequent hierarchical regression analyses illustrated that the age-related changes in selective inhibitory control could not be explained simply by overall slowing or speeding of responses. Findings are discussed in regard to the decay and maturation of selective inhibitory control across the life span.

Adolescent↗

In search of the point of no return: the control of response processes.

Control processes underlying response inhibition were examined. Six Ss performed a visual choice reaction task and were occasionally presented with a tone that told them to withhold the response. Reaction time results were in agreement with a model that assumes a race between response activation and response inhibition processes. Event-related brain potentials, electromyogram, and continuous response measures showed that responses could be interrupted at any time. Evidence was obtained for two inhibitory mechanisms: inhibition of central activation processes and inhibition of transmission of motor commands from central to peripheral structures. Results have implications for the distinction between controlled and ballistic processes.

Adult↗