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Biomedical subjects

Gilberto Bueno Fischer

Publications and source records attributed to Gilberto Bueno Fischer.

7 recordsLinked to original sources

Foreign body aspiration in children.

Foreign body aspiration is a common accident in children and represents an important cause of morbidity and mortality. Diagnosis of this condition demands a high degree of suspicion since physical examination and basic radiology exams have low sensitivity. It is more frequent in children younger than 3 years of age, predominantly boys. Food materials are most commonly involved, particularly peanuts, although this could change according to regional feeding habits. The right main bronchus is the site where foreign bodies are most commonly found. Radiographical findings are not diagnostic, but the presence of unilateral obstructive emphysema or atelectasis are important clues. A rigid endoscopy is indicated whenever there is a suggestive history, since delays in removing foreign bodies can lead to severe bronchial sequelae. In developing countries this type of accident may be more relevant due to the lack of resources and awareness, which can lead to late diagnosis and treatment. Routine preventive measures must be taught to caregivers in order to reduce the incidence. Health care professionals should also be made more aware of the prevalence of this condition.

Age Factors↗

Acute viral bronchiolitis and its sequelae in developing countries.

Acute viral bronchiolitis (AVB) is a common disease found throughout the world. Various aspects of it are being studied: its epidemiology, diagnosis, prognosis and treatment. Most of these studies are being conducted in developed countries, with only a few taking place in developing countries. Risk factors such as poor nutrition, an adverse environment and early weaning should be studied where these features are common. Treatment aspects such as cost-effectiveness in low income settings need further study. Use of ribavirin and respiratory syncytial virus (RSV)-immunoglobulin are good examples. Post-bronchiolitic sequelae also need to be studied in low income countries. There is evidence that bronchiolitis obliterans is unusually frequent in some Latin-American countries such as Argentina and Brazil. It will be helpful to undertake combined studies in countries with the same socio-economics, investigating the preventive and management aspects of AVB and its sequelae to reduce the morbidity and mortality.

Acute Disease↗

Paediatric asthma management in developing countries.

Asthma is a chronic disease that is increasing in prevalence all over the world. The use of inhaled corticosteroids is the main treatment for asthma control. The use of the Global Initiative for Asthma (GINA) guidelines may improve the quality of asthma treatment. Some of the directions in the GINA guidelines may be difficult to apply in developing countries. An important barrier to adequate treatment for asthma in low income countries is the unavailability of inhaled steroids for the general population. Asthma plans must be implemented in these countries with the participation of health systems, medical associations and the pharmaceutical industry. Adaptation of international guidelines to the local situation must occur to make asthma treatment possible for every asthmatic patient. In this paper, we present a review on this subject showing data on the initiatives that significantly improved asthma management.

Age Factors↗

Eosinophilic lung diseases.

In the last 30 years studies have shown that the lungs have been the target of eosinophilic migration producing eosinophilic lung diseases (ELD) secondary to allergens, irritants, parasites, infections, antibodies and drugs. Specific diagnoses can be made by: (1) Peripheral blood eosinophilia and chest X-ray infiltrates. (2) Lung biopsy. (3) Bronchoalveolar lavage (BAL). In developing countries ELD are most frequently associated with parasitic infection. This paper defines, classifies and presents the clinical characteristics and treatment of these diseases with emphasis on parasitic lung problems.

Age Factors↗

Epidemiology, presentation and treatment of pleural effusion.

Pleural effusion (PE) is the most common manifestation of pleural disorders. In children a PE is usually secondary to an underlying disorder. In developing countries PE most frequently results as a complication of a bacterial pneumonia. A high index of suspicion is required in order to avoid delays in diagnosis that may influence treatment and outcome. The diagnosis of PE in children is based on chest radiographs, thoracentesis and pleural fluid analysis. This review discusses the usefulness of diagnostic methods and treatment in children with parapneumonic pleural effusion.

Age Factors↗