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Biomedical subjects

Gilad J Kuperman

Publications and source records attributed to Gilad J Kuperman.

30 records · Page 2Linked to original sources

A computer-based intervention for improving the appropriateness of antiepileptic drug level monitoring.

We designed and implemented 2 automated, computerized screens for use at the time of antiepileptic drug (AED) test order entry to improve appropriateness by reminding physicians when a potentially redundant test was ordered and providing common indications for monitoring and pharmacokinetics of the specific AED. All computerized orders for inpatient serum AED levels during two 3-month periods were included in the study. During the 3-month period after implementation of the automated intervention, 13% of all AED tests ordered were canceled following computerized reminders. For orders appearing redundant, the cancellation rate was 27%. For nonredundant orders, 4% were canceled when information on specific AED monitoring and pharmacokinetics was provided. The cancellation rate was sustained after 4 years. There has been a 19.5% decrease in total AED testing volume since implementation of this intervention, despite a 19.3% increase in overall chemistry test volume. Inappropriateness owing to repeated testing before pharmacologic steady state was reached decreased from 54% of all AED orders to 14.6%. A simple, automated, activity-based intervention targeting a specific test-ordering behavior effectively reduced inappropriate laboratory testing. The sustained benefit supports the idea that computerized interventions may durably affect physician behavior. Computerized delivery of such evidence-based boundary guidelines can help narrow the gap between evidence and practice.

Algorithms↗

Creating an enterprise-wide allergy repository at Partners HealthCare System.

A significant fraction of medication errors and preventable adverse drug events are related to drug-allergy interactions (DAIs). Computerized prescribing can help prevent DAIs, but an accurate record of the patient's allergies is required. At Partners HealthCare System in Boston, the patient's allergy list is distributed across several applications including computer physician order entry (CPOE), the outpatient medical record, pharmacy applications, and nurse charting applications. Currently, each application has access only to its own allergy data. This paper presents details of a project designed to integrate the various allergy repositories at Partners. We present data documenting that patients have allergy data stored in multiple repositories. We give detail about issues we are encountering such as which applications should participate in the repository, whether "NKA" or "NKDA" should be used to document known absence of allergies, and which personnel should be allowed to enter allergies. The issues described in this paper may well be faced by other initiatives intended to create comprehensive allergy repositories.

Boston↗

An online consumer health information resource: 3-year usage summary.

Partners Health Online is a portal to a broad set of consumer health information. As such, the site allows public access to health and disease information as well as Partners-specific information resources (e.g., departments, physicians, clinical trials, classes, support groups). Partners Health Online licenses its health care articles from Healthwise, Inc. This poster describes patterns of activity at Health Online over a 3-year period. The data were analyzed in terms of traffic patterns, visitor characteristics, and information-seeking behavior.

Health Education↗

Primary care clinician attitudes towards electronic clinical reminders and clinical practice guidelines.

Compliance with outpatient practice guidelines is low and clinical reminders have had variable success in improving adherence rates. We surveyed primary care physicians (PCPs) regarding practice guidelines and the perceived utility of electronic reminders for both routine health maintenance (HM) items and chronic disease management. Most PCPs preferred receiving reminders in an electronic format rather than a paper format. Electronic reminders were felt to be more useful for HM items than for diabetes management. The majority of clinicians felt that electronic reminders significantly improved overall health care quality.

Attitude of Health Personnel↗

Defining the priorities and challenges for the adoption of Information Technology in HealthCare: opinions from an expert panel.

The Harvard Interfaculty Initiative developed a tool to assess the level of Information Technology adoption at healthcare organizations and asked an expert panel to rate the clinical functions where IT-based solutions can impact quality of care. The experts were asked to identify high priority areas where IT might impact quality, and to rate the difficulty in implementation associated with that solution. While scores from the expert panel varied widely in assessing difficulties in implementation of IT, there was broad consensus on high priority areas.

Delivery of Health Care↗

KnowledgeLink update: just-in-time context-sensitive information retrieval.

Medical knowledge expands at a pace that makes it impossible for the individual clinician to keep up, especially for medications. Medication-related queries are the most common type of query that typically go unanswered during the course of providing care.1 Unanswered questions may result in errors, as found in one study evaluating systems failures associated with adverse drug events. This study found that better information might have prevented half of serious medication errors, and that lack of drug-specific knowledge accounted for the single largest proportion of these events (29%).2 While this information was available somewhere (either on paper or electronically), it was not at the providers' fingertips. Information technology should anticipate clinicians' needs, and bring the information they require to the point of care. For this purpose, we developed an application extender called KnowledgeLink, which provides "just-in-time" context-sensitive information retrieval for drug-related queries.

Drug Therapy, Computer-Assisted↗

Supporting patient care beyond the clinical encounter: three informatics innovations from partners health care.

As the focus of medicine moves from acute episodic care in the hospital to chronic disease management in outpatients, the primary care physician will play an increasingly important role in the coordination of patient care activities. Traditional outpatient informatics systems have largely focused on the workflow during the clinical encounter. Many tasks, including management of test results,coordination of subspecialty referrals and communication between patients and the practice,remain unsupported. When these tasks are not performed well, quality of care, patient safety and satisfaction may suffer. To address these issues ,Partners Healthcare in Boston, MA has recently developed several applications to address these issues. This demonstration will showcase 3 of these new applications: i) Results Manager, ii) Referrals Manager and iii) Patient Gateway. All interoperate with a browser-based electronic medical record already used by over 500 primary care physicians at Partners Healthcare.

Ambulatory Care↗

End of visit: design considerations for an ambulatory order entry module.

Current paper-based processes for performing billing documentation and test ordering at the end of a clinic visit are fraught with problems, resulting in numerous workflow inefficiencies and significant revenue losses for a healthcare organization. Paper forms are often filled out inaccurately or incompletely, or can be misrouted or lost. Computerizing these processes can alleviate many of these problems. We are building a new module for our ambulatory electronic medical record system to automate these "end of visit" (EOV) activities, which includes completing encounter forms, ordering lab and diagnostic tests, and printing patient visit summaries. An EOV module must be carefully designed to incorporate the needs of clinicians, front office staff, ancillary labs, medical records, and finance departments. An optimally designed EOV system should be customizable to fit into the clinician's workflow, and should help reduce financial losses, improve clinical documentation, and reduce workflow inefficiencies.

Ambulatory Care Information Systems↗

Design and implementation of a comprehensive outpatient Results Manager.

Prior research has demonstrated that clinicians often fail to review and act upon outpatient test results in a timely and appropriate manner. To address this patient safety and quality of care issue, Partners Healthcare has developed a browser-based, provider-centric, comprehensive results management application to help clinic physicians review and act upon test results in a safe, reliable, and efficient manner. The application, called the Results Manager, incorporates extensive decision support features to classify the degree of abnormality for each result, presents guidelines to help clinicians manage abnormal results, allows clinicians to generate result letters to patients with predefined, context-sensitive templates and prompts physicians to set reminders for future testing. In this paper, we outline the design process and functionality of Results Manager. We also discuss its underlying architectural design, which revolves around a clinical event monitor and a rules engine, and the methodological challenges encountered in designing this application.

Ambulatory Care↗

Effective drug-allergy checking: methodological and operational issues.

Adverse drug events cause a large number of injuries, and adverse events caused by medications administered in the face of known allergies represent an important preventable cause of patient harm. Computerized systems can effectively prevent reactions due to known allergies, but building an effective allergy prevention feature is challenging and presents many interesting informatics issues that have both methodological and operational implications. In this paper, we present the experiences from one large delivery system in delivering allergy-related decision support, discuss some of the different approaches that we have used, and then propose a future approach. We also discuss the methodological, behavioral, and operational issues that have arisen which have a major impact on success. Key factors in drug-allergy checking include storing patient allergy data in a single common repository, representing allergy data using suitable terminologies and creating groups of allergies for inferencing purposes, being judicious about which allergy warnings to display, conveying the reaction that the patient has experienced when exposed to the drug to inform the provider of the importance of the warning, and perhaps most important, implementing strategies to optimize the likelihood that allergy information will be entered.

Database Management Systems↗

Real-time notification of laboratory data requested by users through alphanumeric pagers.

The authors developed a novel feature in their clinical information systems, which allows clinicians to request notification about laboratory results. Clinicians who are expecting a particular laboratory result for a particular patient can request a report of the result via an alphanumeric pager as soon as the result is filed into the patient database. This feature has gained popularity and is heavily used in both inpatient and outpatient settings, at a rate of about 2,300 times per month. This event-monitor-based feature illustrates one way that information technology can be applied to improve communication in health care.

Clinical Laboratory Information Systems↗

Automating complex guidelines for chronic disease: lessons learned.

There is scant published experience with implementing complex, multistep computerized practice guidelines for the long-term management of chronic diseases. We have implemented a system for creating, maintaining, and navigating computer-based clinical algorithms integrated with our electronic medical record. This article describes our progress and reports on lessons learned that might guide future work in this field. We discuss issues and obstacles related to choosing and adapting a guideline for electronic implementation, representing and executing the guideline as a computerized algorithm, and integrating it into the clinical workflow of outpatient care. Although obstacles were encountered at each of these steps, the most difficult were related to workflow integration.

Algorithms↗