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Biomedical subjects

Gürcan Aslan

Publications and source records attributed to Gürcan Aslan.

At least 19 recordsLinked to original sources
PubMed2006

Reconstruction of small to medium defects in the soft tissues of the nose with nasalis musculocutaneous V-Y advancement flaps.

Defects in the soft tissues of the nose are usually reconstructed with skin grafts or frontal flaps. However, skin grafts may cause scar tissue and changes in colour. Frontal flaps, however, may be thicker than normal skin and may give unsatisfactory results. Nasalis musculocutaneous V-Y advancement flaps avoid these disadvantages. We suggest an algorithmic approach for the use of these flaps in the reconstruction of small to medium defects in the soft tissues of various regions of the nose. The pedicles of these flaps are the dorsal and lateral nasal arteries. This approach provides a simple, safe, and reliable reconstruction for small and medium defects in the soft tissues of the nose.

Adult↗
PubMed2005

Hemangioma of the lower lip associated with schistosomiasis: a case report.

Hemangiomas may occur in any region of the body, and is the most common tumour of the childhood age. The first case report of multiple Schistosoma mansoni larvae associated with hemangioma of the lower lip is presented. A 7-year-old boy presented with hemangioma of the lower lip. The tumour was subtotally excised under general anaesthesia for aesthetic reasons. The histopathologic diagnosis was multiple Schistosoma mansoni larvae associated with the hemangioma. Patient was treated with an antischistosomal drug.

Child↗
PubMed2005

Effects of 360-degree pedicle torsion on island skin flaps: experimental study in rats.

This study was carried out to observe the isolated effects of pedicle torsion on island skin flaps, without further damaging the pedicle. Twelve adult male Sprague-Dawley rats, weighting 240 to 300 gr, were used, and hexagonal flaps with edges measuring 1.5 cm and pedicles measuring 1 cm in length were raised in the inguinal region. The animals were divided into two groups. In Group A, flaps were re-sutured to the donor beds without any rotation. In Group B, flaps were rotated 360 degrees, applying the same degree of torsion to their pedicles before re-suturing. After 7 days, the percentage of surviving skin areas of the flaps was determined by planimetry, and transverse sections of the flaps and pedicles were taken and evaluated in terms of signs of arterial or venous insufficiency. Statistically significant differences between the groups were determined by analyses using the multiple comparisons test. Pedicle torsion in Group B did not affect flap viability, both macroscopically and microscopically. The presented study shows that 360-degree torsion applied to the pedicle of the flap in this model had no effect on flap viability.

Animals↗
PubMed2005

The fate of transplanted fibrous capsule as an autogenous graft.

BACKGROUND: In reconstructive and aesthetic surgery, several autogenous graft materials and biomaterials are available for soft-tissue augmentation, but none has all the properties of the ideal filler material. The common problem is that heterogeneous material is reactive, and the problem for the autogenous grafts is resorption. METHODS: In this experimental study, the authors examined the transformation that the autogenous graft undergoes in a different location when it is used as a capsule tissue in place of silicone. Whole/diced capsule and fat grafts were evaluated at 3, 6, 9, and 12 months for their volume, weight, and histopathologic and statistical bases. RESULTS: The capsule graft was observed at month 12 as a dense collagen bulk. When it had decreased by 25.6 percent in volume at the end of the 12-month period, the decrease in weight was found to be 20 percent. The resorption rates in diced capsule grafts were 14 percent of volume and 8.6 percent of weight. The volume-based rate of resorption was even lower (63 percent) for the capsule than for the fat, and the weight-based rate of resorption was even lower (70 percent) for the capsule. CONCLUSIONS: The low rate of resorption in capsule grafts was attributed to the environmental conditions that triggered the potential cause of resorption, such as inflammation in the localization conditions when it is was carried from the region where it was formed. The results indicate that in the new localization of the capsule tissue that is developed against silicone, it behaves as an autogenous graft that it is resorbed at a lower rate.

Adipose Tissue↗
PubMed2005

Upper eyelid full-thickness skin graft in facial reconstruction.

BACKGROUND: The potentially available upper eyelid skin, as an alternative donor site, deserves more attention in clinical use. OBJECTIVE: The objective of this study was to prospectively evaluate the clinical behavioral characteristics of upper eyelid full-thickness skin grafts in facial reconstruction. METHODS: Sixteen patients who concluded the 12-month follow-up period were included in the study. Graft dimensions were measured in place before the graft harvest. Defect sizes were measured following lesion excision and postgrafting. Graft sizes were measured postoperatively at 1, 3, 6, and 12 months. RESULTS: The largest and smallest grafts were 46 x 22 mm and 40 x 15 mm (average 43.1 x 19.3 mm) in size, respectively. The largest and smallest defect dimensions were 33 x 23 mm and 17 x 9 mm (average 22.6 x 15.6 mm), respectively. The average postgrafting size was 21.1 x 14.6 mm. Grafts and donor sites healed very well. Generally, an acceptable to good texture and color match was observed beyond 6 months. Wound bed contraction was not observed beyond the first month (p<.05). CONCLUSION: Special characteristics of hairless skin, good color and texture matching, and inconspicuous and hidden donor scar make the upper eyelid a good alternative donor site for small- to medium-sized facial skin defects. The main disadvantages that limit its clinical use are the age of the patient, a lack of adnexal structures, comparatively limited sun exposure, and possible insufficient thickness, especially when deep defects are of concern.

Aged↗
PubMed2005

Squamous cell carcinoma of the lower lip: exact location match in siblings.

BACKGROUND: In recent years, genetic contribution to the development of skin cancers is under the magnifying glass of several authors and is now regarded as the main initial etiology in carcinogenesis. OBJECTIVE: Two siblings who had squamous cell carcinoma of the lower lip showing an exact location match are presented. PATIENTS: They did not share common environmental factors, and there was no history of tobacco and/or alcohol abuse. CONCLUSIONS: It would be scientifically deceptive to draw generous conclusions for the cases here, other than being a very interesting and unusual coincidence, because further evaluation could not be done to scientifically prove a possible genetic contribution.

Carcinoma, Squamous Cell↗
PubMed2005

[The relationship between the fracture site and etiology in mandibular fractures].

OBJECTIVES: The aim of this study was to evaluate the relationship between the fracture site and etiology in mandibular fractures. PATIENTS AND METHODS: The study included 37 patients (61 fracture sites) (29 males, 8 females; mean age 26 years; range 1.5 to 77 years) who underwent surgical treatment for mandibular fractures between May 2001 and November 2003. Data on epidemiological characteristics of patients, etiology and fracture sites were retrospectively reviewed. RESULTS: Of the patient group, 51.3% had a single, 48.6% had two or more fractures. Seventy-five percent of the assault victims had more than one fracture site. Motor vehicle accidents accounted for 36% of all the fracture sites. The most common locations of the fractures according to the etiology were as follows: fractures caused by motor vehicle accidents at the parasymphyseal area, by falls at the condyle, and by assaults at the parasymphyseal and angular areas. All the fractures resulting from bicycle accidents occurred at the condyle area. CONCLUSION: It is advisable to be more attentive for condyle fractures when confronted with any etiology of mandibular fractures. Etiology may be suggestive of the fracture site(s).

Adolescent↗
PubMed2004

The influence of sildenafil on random skin flap survival in rats: an experimental study.

Sildenafil (Viagra), a selective and specific inhibitor of cyclic guanosine monophosphate (cGMP) phosphodiesterases (PDEs), is currently marketed for the treatment of erectile dysfunction. Sildenafil is a potent and highly selective PDE-V inhibitor and enhances smooth muscle relaxation in human. Systemic arterial and venous smooth muscle cells contain PDE-V and nitric oxide (NO) which is a major mediator of relaxation of the smooth muscle cell. The aim of the present study is to investigate, in a rat model, the potential effect of sildenafil on survival of random pattern skin flaps. For this purpose, 32 Sprague-Dawley rats were used and a McFarlane-type caudally based skin flap was designed on the dorsum of the rat (2.5 x 8 cm). Rats were divided into four groups: One control (Group D), and three treatment groups (Groups A, B, C). Sildenafil was administered orally to the experiment groups; Group A: 3 mg/kg/single dose a day, Group B: 10 mg/kg/single dose a day and Group C: 10 mg/kg/twice dose a day. The areas of flap necrosis were measured in each group. The extent of viable flap areas were expressed as a percentage of total flap area, and differences were studied by Completely Randomised Experimental design. The areas of necrosis of skin flaps decreased depending on sildenafil dose, but viability of the flaps treated with 3 mg/kg/day was not different than the control group. The flaps receiving 2 x 10 mg/kg/day sildenafil gave the highest (P < 0.01) survival rate. As a conclusion, sildenafil may have a dose dependent effect to increase flap survival in random skin flaps.

Animals↗
PubMed2004

The value of medical leeches in the treatment of class IIC ring avulsion injuries: report of 2 cases.

Ring avulsion injuries pose a serious problem for the hand surgeon. According to the severity of the injury several classifications and their modifications have been proposed. In class IIC ring avulsion injuries arterial circulation is intact but only the venous supply is disrupted. Several therapeutic approaches have been suggested for these types of injuries. We present two class IIC cases that were treated successfully solely with leeches, with excellent results. Although the method is not a substitute for microvascular intervention leeches can be used when the clinical condition of a patient does not permit a lengthy surgery and if microvascular techniques fail or are thought to be pointless.

Adult↗
PubMed2004

A new phenomenon: "sleep lines" on the face.

Plastic surgery must achieve the best cosmetic results, and it helps to consider certain skin lines. Aging and scars can cause the face to become lined, and we have noticed various facial lines among patients or their relations who have come to our outpatient clinic. These lines are sometimes single and there are sometimes 2-3 parallel lines generally in the same area of the face, such as the lateral orbital, temporal, frontal, and buccal regions. After detailed evaluation, we concluded that these oblique or horizontal wrinkles were caused by the position in which they slept. All of them slept prone, with their faces buried in the pillow, which over many years has caused wrinkling of the skin. We think therefore that sleeping position should be considered as an aetiological factor in the formation of wrinkles. The lines that should be taken into consideration during operation are Langer's lines, or relaxed skin tension lines, but not sleep lines. Here we describe the possible aetiology of sleep lines on the face.

Face↗
PubMed2004

Injuries to children's hands caused by the engine belts of agricultural machines: classification and treatment.

Injuries to children's hands with farm machinery, particularly tractors, are common in rural areas. We present 58 cases of hand injuries in children aged from 3 to 7 (mean 4.5), caused by the engine belts of agricultural vehicles, who were referred from the cities in Central Anatolia. The injury patterns among patients were similar. The injury generally starts from the middle phalanx of the third finger, crosses the proximal phalanx of the fourth finger and ends in the hypothenar region. The patients were categorised into five groups and treatment planned accordingly. The most commonly involved digit was the third finger and the thumb the least. Surgical treatment depended on the severity of the injury and included primary closure of the lacerations, tendon repair, fixation of fractures, grafting, and local flaps. Results of these injuries are generally poor, so prevention is more important.

Accidents, Home↗
PubMed2004

Consequences of radiation accidents.

Radiation injury attributable to radiotherapy is a topic that has attracted ample attention in the literature, especially in a vast number of publications in plastic surgery. However, the literature is clearly devoid of compilations regarding the effects of ionized radiation accidents. A case of a radiation accident is presented. It is nearly impossible to anticipate the extent of effects of external irradiation of the skin and subcutaneous tissues. The initially healed area should be expected to show late recurrent necrosis. Patients exposed to ionized external irradiation are no longer radioactive and can be treated as ordinary patients. However, these patients should be followed closely for years, keeping in mind the onset of late radiation effects like skin necrosis in various parts of the body, skin and other organ cancers, leukemia, infertility, hypothyroidism, and cataracts.

Adult↗
PubMed2004

The prepuce and circumcision: dual application as a graft.

Circumcision is probably one of the first plastic surgery operations that has been used for centuries. The aim of this study was to apply the bilamellar tissue (skin and mucosa) obtained from circumcision to various defects and to evaluate the clinical results. During the last 2 years, 19 patients have been operated, and the skin and mucosal grafts were applied individually or simultaneously. The etiology was trauma for the whole series of patients (12 burns and 7 strap injuries). In 15 patients the defect was localized to the hand whereas in 4 patients it was located on the dorsum of the foot. In 10 patients, mucosa and skin graft were applied to the same defect as a single, compact layer. In 9 patients, skin and mucosa were applied separately to multiple defects. Using these methods, comparative evaluation of the consequences of prepuce mucosal and skin graft applications could be made. Four obvious differences were observed: (1) in mucosal grafts, early graft edema that resolves spontaneously after 48 hours; (2) better adaptation of the mucosal grafts to the recipient bed; (3) hyperpigmentation in both graft types, but the skin part was slightly darker than the mucosa; and (4) less secondary contraction was seen in mucosal grafts. The results were evaluated in light of the authors' knowledge of the prepuce as an alternative full-thickness donor site. The relative differences in the dual anatomic structure of mucosa and skin, and the role of circumcision as a medical, cultural, and religious application in some societies are discussed.

Adolescent↗
PubMed2004

Giant lipomas: a series of 12 consecutive cases and a giant liposarcoma of the thigh.

BACKGROUND: The clinical presentation and character of giant lipomas create diagnostic problems because of their close relationship with other mesenchymal benign and malign tumors. It is therefore of primary importance for the clinician to be familiar with epidemiologic and anatomic attributes of these lesions. OBJECTIVE: To evaluate and compare epidemiologic and clinical characteristics of giant lipomas operated in our clinic. METHODS: Twelve giant lipomas and one giant liposarcoma are included in the study. RESULTS: There were seven females and six males. The patients ranged in age between 22 and 75. The tumor duration was between 2 months and 40 years. The smallest lipoma size was 10x5x3 cm, and the largest was 19x9x5 cm. Two of the lipomas were located intermuscular. Mild hematoma formation was observed in two patients. Histopathologic evaluation was done for all specimens, and one myxoid liposarcoma was encountered. CONCLUSION: When dealing with giant lipomas, liposarcomas should always be included in the differential diagnosis.

Adult↗
PubMed2004

EMLA and ear surgery: is it possible to achieve full-thickness anesthesia with EMLA?

BACKGROUND: Topical local anesthetic applications offer painless, effective analgesia with slow onset but prolonged duration and minimal side effects. EMLA (Eczacibasi Pharmaceuticals, Istanbul, Turkey) is the most universally used topical local anesthetic. OBJECTIVE: The aim of this prospective, randomized, double-blind study is to evaluate the efficacy of EMLA on total anesthesia of the external ear. METHODS: Twenty-two patients with helical lesions were divided into two groups. Group A received EMLA on both the anterior and posterior surfaces of the ear, and group B received EMLA on only one side of the ear. After 120 minutes of occlusive dressing, the surgery was performed. The short form of the McGill Pain Questionnaire and a numerical visual analog scale were used to measure overall pain quality and intensity during and at the end of surgery. RESULTS: Visual analog scale scores (four for group A and six for group B6) between two groups using Student's t-test (p=0210) and concerning McGill Pain Questionnaire scores with Wilcoxon signed ranks test (p=0.058) between two groups showed no statistical significant difference. CONCLUSION: It seems that EMLA cream is not a good and first option for achieving full anesthesia on the ear because of its poor anesthetic effect. We do not consider EMLA cream to be clinically useful for major surgical attempt on the ear.

Adolescent↗