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Biomedical subjects

Gökhan Adanali

Publications and source records attributed to Gökhan Adanali.

6 recordsLinked to original sources

Ameloblastic carcinoma arising from anterior skull base.

Ameloblastic carcinoma (AC) is an aggressive malignant epithelial odontogenic tumor. It may appear de novo or originate from a pre-existing ameloblastoma or odontogenic cyst. To our knowledge, an AC that originates from the anterior skull base has not been reported before in the English literature. We report a case of an AC that originated from the anterior skull base and invaded the dura of the anterior fossa and discuss its clinical course and treatment.

Case Reports↗

Disseminated squamous cell carcinoma of the skin.

BACKGROUND: Squamous cell carcinoma (SCC) accounts for a large proportion of nonmelanoma skin cancers. It may appear mainly on the skin and the mucous membranes; however, it may also appear on any part of the body. The tumor originates from atypical keratinocytes. This tumor, which can be locally destructive, has a metastasis rate of 5% to 10%. OBJECTIVE: To present a patient with disseminated primary SCC of the skin. METHODS: In this report, we present a unique case of disseminated SCC that is thought to be primary. As far as we know, the patient neither had any syndrome or a disease predisposing to SCC nor was exposed to toxic substances or ionized radiation. The disease progressed in a very short period. To our knowledge, there has not so far been a case of disseminated primary SCC. The patient was inoperable when he presented to our clinic. RESULTS: Chemotherapy was instituted in the Department of Medical Oncology; unfortunately, the patient died while on the therapy. CONCLUSION: An original case of disseminated SCC of the skin is presented.

Carcinoma, Squamous Cell↗