Biomedical subjects
G de Virgiliis
Publications and source records attributed to G de Virgiliis.
Age-related frequency of viral lesions and their association with uterine cervical intraepithelial neoplasia.
Data collection forms of 50,165 routine smears were examined, and of these 47,577 were considered for this study. Viral cytological lesions (VL) were observed in 101 cases: of these, 19 were associated with cervical intraepithelial neoplasia. The total frequency of VL was 0.21%, with the peak in the teenager group (0.49%). The frequency of CIN among VL showed an overall frequency of 18.8%: this was null under 21 years of age and highest (50%) between 51 and 60 years of age. The frequency of VL in relation to clinical provenance of patients and the season of the year did not attain significance.
Peculiar ruthenium red staining pattern of the human early trophoblast.
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The junctional pattern of the human villous trophoblast. A freeze-fracture study.
This investigation of the junctional pattern of the human trophoblastic epithelium was carried out on the fractured faces of (a) the syncytial plasma membrane bathed by the maternal blood (S-PMm); (b) by syncytial plasma membrane in contact with either the cytotrophoblast or the trophoblastic basement membrane (S-PMf), and (c) the cytotrophoblastic plasma membrane (C-PM). The most relevant findings were tight junctions on the SPMm, and the intertrophoblastic junctional pattern, not realizing a tight subcompartmentalization between syncytium and cytotrophoblast. The following aspects were discussed: the SPMf represents the last membrane barrier before the fetal capillary, and the function of the cytotrophoblast seems to be limited to the modulation of syncytial activity.
Ultrastructure of the adenohypophysis following ovariectomy and treatment with estrogens and progesterone.
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[Modifications of the pituitary gland after treatment with norethindrone-mestranol. An electron microscope study].
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[Proliferation of fibroblasts in the hypertrophic cicatrix].
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Connective tissue regeneration after laser-CO2 therapy.
The ultrastructural pattern of fibroblasts involved in the healing process of laser-treated tissues has been investigated. This study has been performed on the uterine cervix, the epithelial abnormalities of which are frequently treated by laser. Observations carried out immediately and two and seven days after treatment, have demonstrated that: fibroblasts show an active and almost uniform pattern; myofibroblasts are not present; and macrophages are limited in number. This healing process is interpreted as a proliferative pattern of the connective tissue which differs from that of some benign tumors and of healing wounds.