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Biomedical subjects

G Zeilig

Publications and source records attributed to G Zeilig.

At least 19 recordsLinked to original sources
PubMed1996

Insulin resistance in paraplegics--effect of one bout of acute exercise.

Insulin action was assessed in spinal cord injured (SCI) male individuals (n = 5) and compared to controls (C) (n = 5). Mean (+/-SD) age and body weight were 27.0 +/- 5.1 and 24.5 +/- 1.6 years and 68.6 +/- 3.2 and 76.6 +/- 5.0 kg for SCI and C group, respectively. Subjects performed physical activities 2-3 times/week on a non-competitive basis. Using the euglycemic clamp, metabolic clearance rate of glucose (g-MCR) was measured twice, one week apart; at a basal state and then 1 h after aerobic exercise. Exercise consisted of 60 min arm-crank at 20-25 watt and 60 rpm. During the hyperinsulinemic clamp, insulin concentration was 76 +/- 14 and 67 +/- 9 microU.ml-1, in SCI and in controls, respectively. At baseline, g-MCR was comparable in SCI and C individuals (8.1 +/- 2.4 and 8.0 +/- 2.1 ml.kg-1.min-1, respectively). After exercise, g-MCR remained at 7.9 +/- 2.0 and 8.5 +/- 2.6 ml.kg-1.min-1 in SCI and C, respectively. In spite of muscle atrophy, peripheral sensitivity to insulin was not impaired in paraplegics. No increase in insulin response to the exercise stimulus was seen in any of the groups. It may thus be suggested that the daily level of activity and the physical training performed by paraplegics, are sufficient to eliminate a state of insulin resistance, which often develops in extremely sedentary populations.

Adult↗
PubMed1996

Pathological laughter and crying in patients with closed traumatic brain injury.

We report on the clinical and radiological features in 16 adult patients who suffered a traumatic brain injury and subsequently developed pathological laughter and crying. Patients with pathological laughter and crying were identified from among 301 consecutive brain-injured admissions to a trauma centre and subsequently to a rehabilitation facility. Patients displaying pathological laughter and crying had a greater severity of injury than patients without the syndrome; they also had other associated neurological features compatible with pseudobulbar palsy. Pathological laughter alone, or combined with crying, was more frequent than crying alone. An attempt to correlate clinical features with focal lesions on neuroimaging studies yielded inconsistent results. The theoretical anatomical substrate for pathological laughter and crying in patients with traumatic brain injury is discussed.

Adolescent↗
PubMed1995

Paraplegia following surgical correction of scoliosis with Cotrel-Dubousset instrumentation.

Three patients with paraplegia following corrective surgery for idiopathic scoliosis, using the Cotrel-Dubousset (CD) instrumentation, were admitted to our department over a period of 22 months. They were operated on by three different surgeons and they were the first serious neurological complications in these surgeons' careers. The monitoring method was the "wake-up" test, applied at the end of the correction maneuver with the instrument. One patient presented paraplegia at the "wake-up" test and the other two were paraplegic shortly after ceasing anesthesia. Electrophysiological spinal cord monitoring during surgery may reduce the risks of complications.

Adolescent↗
PubMed1992

[Spinal cord injuries caused by aviation accidents].

During the past 15 years fewer than 1% of those treated in the National Spinal Cord Injury Center were injured as a result of aviation accidents. In addition to 9 such patients treated at the center since 1973, another 6 were found among the many hundreds receiving ambulatory care in our clinics. 3 patients had survived a helicopter crash, 2 were injured while ejecting from combat aircraft, 3 were injured in crashes of light aircraft, 1 fell from a hand glider and 6 were injured in parachute drops. Of the 15 reviewed, 6 use wheelchairs, 3 walk assisted by orthopedic devices, while 6 ambulate freely. Although initial hospitalization was not substantially longer than in other patients with spinal cord injuries, extended ambulatory psychological intervention was necessary.

Accidents, Aviation↗
PubMed1992

Long term follow up of patients with cauda equina syndrome due to intraspinal lipoma.

We have had the opportunity to treat and follow up two young males with cauda equina syndromes after recurrent resection of intraspinal lipomas. This condition is relatively rare. The patients underwent myelographies, operations, long periods of hospitalisation, and rehabilitation. The syndromes included low back pain, arachnoiditis, and recurrence of the lipoma after several years and multiple operations. These are the problems that we were faced with: (1) Although the tumor is benign it is impossible to resect it completely. (2) There are complications which interfere with rehabilitation, including pain, arachnoiditis, and neurological deterioration. (3) Long term prognosis might be grave and the patient and family should know this. (4) Physiotherapy and sports: should these patients perform strenuous exercise or not?

Adult↗
PubMed1989

Spinal cord injury associated with blunt traumatic rupture of the diaphragm.

The incidence of spinal cord injury associated with blunt traumatic rupture of the diaphragm is extremely low and rarely mentioned in the numerous reports about rupture of the diaphragm. It is thought that more such cases can be found among the fatalities of aircraft accidents and presumably among the fatalities of road traffic accidents as the forces causing such injuries make it unlikely for the casualty to survive. The authors present six cases encountered at Stoke Mandeville Hospital, England, and at Sheba Medical Centre, Israel. Although the mortality of such cases, if the patient survives the original impact, is usually due to associated injuries, early diagnosis is essential as late complications increase the incidence of delayed mortality.

Adolescent↗
PubMed1989

'Duplicate limbs' sensation in acute traumatic quadriplegia.

A 64-year-old man sustained acute quadriplegia due to a traffic accident, while in the midst of a petit mal seizure. After recovery from the initial medical complications he developed a duplicate limb phenomenon. The patient felt that another pair of upper and lower limbs had grown from his body, parallel to the paralysed limbs. To the best of our knowledge this duplicate phenomenon in all limbs has not been described before in a traumatic quadriplegic patient. It is our impression that this phenomenon is a rare example of preoccupation with the paralytic limbs, of sensory deprivation with a (possible) unusual drug reaction.

Humans↗
PubMed1989

Hyperprolactinemia, galactorrhea and amenorrhea in women with a spinal cord injury.

Six women with a traumatic spinal cord injury (SCI) developed hyperprolactinemia, amenorrhea and galactorrhea. Five of them had thoracic level lesions and 1 had a lumbosacral lesion. Two were postpartum and 1 was pregnant at the time of injury. Transient diabetes insipidus developed in 1 patient. Temporary administration of bromocriptine decreased prolactin levels, caused cessation of lactation and restored ovulatory cycles. The syndrome disappeared spontaneously in all 6 patients. Pituitary stalk concussion resulting from the trauma might cause this phenomenon, with the level of the cord injury playing a role. Being pregnant or early postpartum can predispose women to develop this syndrome.

Adult↗
PubMed1988

Massive centrifugal multitrauma resulting in paralysis and limb loss. A report of 4 cases and discussion of the special problems in rehabilitation.

Four cases are described wherein massive centrifugal trauma caused a whirl-whiplash type injury to the spinal cord resulting in paralysis. Two patients became paraplegics and two quadriplegics. In three cases, there was a loss of one or more limbs associated with other concomitant injuries. Attention is focused on the problems facing patients with a combination of plegias and amputation.

Adolescent↗