Biomedical subjects

G Zeiler

Publications and source records attributed to G Zeiler.

At least 19 recordsLinked to original sources

PubMed2006

[Allergic reaction to components of bone cement after total knee arthroplasty].

There are many reports about allergic reactions in association with total hip or knee arthroplasty. While most studies focus on allergic reactions to metallic components, only few reports exist about reactions to bone cement or its ingredients. We report about a patient who developed eczema at the knee and the lower leg one year after cemented TKR. Patch testing showed as potential causes contact allergic reactions to nickel and benzoylperoxide, an ingredient of the here used bone cement. The local and temporal association between onset of eczema and knee arthroplasty suggests a causal link. Benzoylperoxide as potential contact allergen in bone cement is so far almost neglected. The development of extended testing procedures and data collection should provide further information and better care of these patients. The development of special bone cements for patients with allergic diathesis is requested.

Arthroplasty, Replacement, Knee↗

PubMed2006

[Melorheostosis of the foot: a case report of a rare entity].

INTRODUCTION: Melorheostosis is a rare bony dysplasia and often recognised just sporadically by chance. CASE REPORT: We present a case of a 15 year old girl who presented a melorheostosis of the left foot. After birth there was recognized a shortening and deformity of the 2nd toe on the left foot. Furthermore she had an interphalangeal hallux valgus that displaced the 2nd toe increasingly. Thus in the last years there were more and more difficulties to wear normal shoes. Conservative therapy was not successful. We performed a lengthening extending osteotomy of the 2nd toe (a modified Weil osteotomy) and an Akin osteotomy of the interphalangeal hallux valgus. Since the surgical procedure the patient is out of any complaints. DISCUSSION: We demonstrate the radiologic and histologic findings and discuss the relevant literature and possible etiology.

Adolescent↗

PubMed2005

[Results and experiences of conversion of hip arthrodesis ].

INTRODUCTION: With the predictably good outcome of total hip arthroplasty today (THA), hip arthrodesis currently has limited indications. Over the long term, however, most patients develop secondary degenerative arthritis in the spine, contralateral hip, and ipsilateral knee due to overloading. The deteriorating condition of these joints eventually causes the onset of pain, which often requires conversion of a fused hip to a THA. The results and experiences of conversions of a hip arthrodesis into a THA are reported. INTRODUCTION: Between 1 January 1985 and 31 December 2001 conversion of a previously performed arthrodesis of the hip to THA was carried out in a total of 45 patients; 34 patients could be followed up after the conversion to THA after a mean of 77.5 months (min.: 24, max.: 208). The primary indications for the conversion were low back pain (n=21) and ipsilateral knee pain (n=13). RESULTS: The mean age at the time of THA was 75.3 years (min.: 32, max.: 74). The mean time interval between the arthrodesis and the conversion to THA was 30.4 years (min.: 5, max.: 66). Of 34 hips, 29 (85%) were either pain free or had minimal pain. Complications included one persisting sciatic nerve palsy, two superficial infections, two periprosthetic fractures, and two heterotopic ossifications IV degrees with one recurrence of ankylosis and one marked reduction of motion. Revision arthroplasty was performed in four hips. Postoperatively 7 patients showed no limping, 11 showed a slight limp, and 17 a pronounced limp. Recurrent dislocations occurred in one patient. CONCLUSION: We conclude that this operation can lead to satisfactory results even after a long duration of the arthrodesis. There is a high rate of complications after conversion of a hip arthrodesis to a total hip arthroplasty. These issues must be carefully considered and discussed with the patient before any conversion procedure.

Adult↗

PubMed2005

[Experiences with the Butler procedure for overlapping fifth toe].

UNLABELLED: Overlapping fifth toe is a finding in pediatric orthopaedics which rarely requires operative therapy. PATIENTS AND METHOD: Between Jan. 1, 1992 and Dec. 31, 2002 five operations of an overlapping fifth toe using the Butler procedure were performed at a mean patients age of 5.5 years (min: 3, max: 9). All patients were clinically evaluated after a mean follow-up of 6 years (min: 2, max: 10) according to the score of Black. We present the technique of the Butler procedure and discuss the relevant literature. RESULTS: An excellent result was achieved in all patients. Despite the extensive soft tissue release no complications could be found. CONCLUSION: The Butler procedure is a simple and safe procedure without any need of immobilisation.

Arthroplasty↗

PubMed2005

[The modified Brooker classification for evaluation of heterotopic ossifications in total hip replacement].

INTRODUCTION: To evaluate heterotopic ossifications (HTO) in total hip replacement several classifications have been developed. Most often the classifications according to Brooker or Arcq are used. These systems enable the description of HTO on x-rays in ap view, functional aspects like range of motion are not evaluated. In several studies we could observe that patients with HTO IV degrees according to Brooker ("ankylosis") had a free or excellent range of motion. We introduce a modified Brooker classification system which enables the evaluation of HTO in two X-ray planes and allows in addition a description of hip function. PATIENTS AND METHOD: On the a.-p. X-ray view the original Brooker classification is used, on the lateral view the Brooker classification ventrally and dorsally of the longitudinal axis of the stem of the total hip replacement is used. In addition functional deficits as a sequalae of HTO are documented (1: yes; 2: no). The new classification system is used in 10 cases with HTO IV degrees according to Brooker in the a.-p .view. RESULTS: 8 cases with "ankylosis" according to Brooker showed a good range of motion. In these cases HTO I-III degrees according to Brooker were found in the lateral view. In the ap view these HTO were evaluated as HTO IV degrees because of an overlapping effect. DISCUSSION: The new classification using X-rays in two planes allows to describe HTO sufficiently especially in respect to hip function. The most important advantage of this new classification is the fact that it modifies only a widly used and accepted system. This may lead to a high acceptance of the new classification.

Ankylosis↗

PubMed2005

[Results of operative therapy of idiopathic clubfoot using a dorsomedial approach with soft tissue preparation "à la carte"].

INTRODUCTION: Several concepts have been published for therapy of idiopathic clubfoot. Actually the Cincinnati approach is the "gold-standard" in operative treatment of idiopathic clubfoot. Using this approach delayed wound healing and overcorrection are wellknown complications. During the last 30 years a dorsomedial approach is used in operative treatment of idiopathic clubfoot in our clinic. Using this approach a dorsal, medial and/or lateral release can be performed. Postoperatively a plaster cast is used. The following years a rigid therapy with orthosis and support is requested. PATIENTS AND METHOD: Between June 1986 and December 2000 130 clubfoot operations with soft tissue release were performed. 119/130 (91 %) patients could be clinically and radiologically followed-up after a mean of 4.5 years (min: 2, max: 17) including 65.5 % male and 34.5 % female patients. Average age at time of operation was 7.6 months. The findings were classified according to Dimeglio. To evaluate the clinical results the score according to Laaveg and Ponseti was used. X-rays with load (a. p. and lateral view) were evaluated preoperatively and at follow-up for a. p. and lateral talocalcaneal angle, talometatarsal-I-angle, calcaneometatarsal-V-angle and the angle of the first ray. Additionally complications and recurrences were documented. RESULTS: 21.8 % of the feet were classified IV degrees , 39.5 % III degrees and 38.7 % II degrees according to Dimeglio. Recurrent clubfoot was found in 7.6 % of all cases. All angles showed a significant improve. At latest follow-up 95.6 +/- 9.2 points according to the score of Laaveg and Ponseti were achieved. Flat top talus was found in 37 cases. CONCLUSION: The dorsomedial approach allows an excellent correction of clubfeet with a low rate of complications and recurrences in comparison to other studies.

Achilles Tendon↗

PubMed2004

[Titanium modular revision prosthesis stem in revision hip prosthesis].

In revision arthroplasty of the hip, femoral defects and fractures must be bridged by a long stem. The implant has to be adapted exactly to the diameter of the cortical tube and has to be placed distally beyond the pathologic area. The titanium modular revision prosthesis (MRP) stem consists of the titanium alloy Ti6Al7Nb and is offered in various diameters, lengths, and special devices, which allows individual and load-stable reconstruction. The aim of the current study is to scrutinize first clinical and radiological results of the titanium MRP revision stem in revision arthroplasty of the hip. We report the midterm results of 130 non-cemented revision arthroplasties of the hip using the titanium MRP revision stem with a mean follow-up of 2.9 years (minimum: 1 year, maximum: 8 years), including 56 men and 74 women. The indication for revision arthroplasty was aseptic loosening of the cup and stem in 94 cases, loosening of the stem in 17 cases, reimplantation in a Girdlestone situation in 11, and periprosthetic fractures in 8 cases. The Harris hip score improved from 50.9+/-24.6 preoperatively to 88.5+/-11.5 postoperatively. The score according to Merle d'Aubigné improved from 9.8+/-4.0 preoperatively to 15.2+/-2.8 postoperatively. We found three recurrent dislocations, two lesions of the sciatic nerve, three cases of persisting deep infection, two periprosthetic fractures, and one case of subsidence of the stem of 2 cm required revision of the MRP stem. Atrophy of the proximal femur was visible in all cases with a stem diameter >17 mm (39/130). Stable primary fixation was achieved in 129 of 130 cases. The titanium MRP revision has proved to be a very reliable implant in cementless revision arthroplasty of the hip.

Aged↗

PubMed2004

[Bilateral localized osteolysis after cemented total hip replacement].

The incidence of focal progressive osteolysis after THR is about 8% and 56%. Most often osteolysis is correlated with macrophage-induced osteoclastic bone resorption as a sequel of inflammatory reaction to wear particles. Recently these findings were published in respect to allergic reactions to implants, their alloying constituents, or bone cement. We report about a patient who developed bilateral localized osteolysis just below the cement mantle 5 years after cemented THR with a Müller straight stem. In the middle of the osteolysis small fragments of bone cement could be detected. Epicutaneous testing showed no reaction against cobalt, chromium, or nickel. Further epicutaneous testing in respect to ingredients of the bone cement were refused by the patient. Histological examination revealed a histiocytic reaction to wear particles and surrounding giant cells. To our knowledge, this is the first case of bilateral localized osteolysis after cemented total hip replacement. Taking all results of the current case into account, it is still unclear if a lymphocytic allergic contact reaction did contribute to the sequel of this case. Reports of immunologically induced incompatibility to components of bone cement, the development of extended testing procedures, and further scientific research should contribute to optimizing the care of patients.

Bone Cements↗

PubMed2004

[Delayed paresis of the femoral nerve after total hip arthroplasty associated with hereditary neuropathy with liability to pressure palsies (HNPP)].

Delayed lesions of the femoral or sciatic nerve are a rare complication after total hip arthroplasty. Several cases in association with cement edges, scar tissue, broken cerclages, deep hematoma, or reinforcement rings have been published. We report about a 62-year-old female who developed a pure motor paresis of the quadriceps muscle 2 weeks after total hip arthroplasty. After electrophysiological evaluation had revealed an isolated femoral nerve lesion, revision of the femoral nerve was performed. During operative revision no pathologic findings could be seen. One week later the patient developed paralysis of the left wrist and finger extensors after using crutches. Electrophysiological evaluation revealed several nerve conduction blocks in physiological entrapments and the diagnosis of hereditary neuropathy with liability to pressure palsies (HNPP) was established. Hereditary neuropathy with liability to pressure palsies (HNPP) is a rare disease with increased vulnerability of the peripheral nerve system with mostly reversible sensorimotor deficits. It should be taken into consideration in cases of atypical findings of compression syndromes of peripheral nerves or delayed neuropathy, e. g., after total hip arthroplasty.

Arthroplasty, Replacement, Hip↗

PubMed2004

[Surface characterization of Al2O3-blasted titanium implants in total hip arthroplasty].

INTRODUCTION: Shot peening and grit blasting techniques are used in several surface modifications for producing hip endoprostheses. Corund blasting techniques using highly pure Al2O3 particles to create a rough surface of titanium implants in cementless total hip arthroplasty achieve better osteointegration. An increasing number of publications in maxillofacial surgery and orthopedic surgery show that there is a significant contamination on corund-blasted surfaces. The latest research studies reported an effect of contaminant particles on early failure of endoprostheses associated with third body wear. The aim of our work was to evaluate the amount and particle size of Al2O3 on the implant surface. MATERIAL AND METHOD: The surface of four different geometries (five parts each, ARR titanium acetabular reinforcement ring, anisotropic Vektor cup, Vektor titanium stem and modular MRP Titan stem) were analyzed with respect to Al2O3 particles. Grit blasting was performed with Al2O3 particles, Alodur SWSK, Fa. Treibacher. Field emission scanning electron microscopy (LEO 1525) was used for the detection of the Al2O3 particles at the implant surface with a backscattered electron detector. The particle size distribution as well as the average area of the covered surface was calculated with image analyzing software (analySIS, Soft Imaging System GmbH). RESULTS: The surface of the anisotropic Vektor cup was contaminated at an average of 41.7+/-4.9%, the Vektor titanium stem at an average of 33.3+/-4.7%, the (MRP) Titan stem at an average of 30.6+/-4.2%, and the ARR titanium acetabular reinforcement ring at an average of 23.2+/-1.6 with Al2O3 particles over the whole surface orientated to the bone. DISCUSSION: The results of this study clearly show that there is contamination of rough titanium surfaces with Al2O3 particles at an unexpectedly high percentage. With respect to third body wear in total hip arthroplasty, further studies are necessary to minimize contamination of roughened surfaces and maintain sufficient roughness for osteointegration.

Aluminum Oxide↗

PubMed2004

[Titanium deposits on the ceramic heads of dislocated total hip replacements].

INTRODUCTION: In cases of revision total hip replacement (THR) having acetabular titanium components with dislocations in the past, metallic deposits are frequently found on the ceramic heads. The aim of this study was to determine whether the metallic deposits increase surface roughness in definite areas. MATERIALS AND METHODS: Ten ceramic heads of revised THR which showed metallic deposits were investigated. The patients suffered from one to six dislocations. The prosthesis lifetime ranged from 2 weeks to 12 years. Surface structure was investigated in a scanning electron microscope (LEO 1525), and the metallic deposits characterised by means of energy dispersive x-ray analysis (EDX). RESULTS: In the area of the metallic deposits, titanium was detected by EDX. Edges with a significant increase in surface roughness were observed, partially accompanied by damage to the surface structure and loosening of Al(2)O(3) particles. DISCUSSION: Titanium deposits increase surface roughness in definite areas, which probably causes wear to the ceramic-ceramic or ceramic-polyethylene articulations due to different roughness values and surface properties. Further investigations are necessary in order to determine the importance of these findings with respect to wear and loosening of total hip arthroplasty.

Aged↗

PubMed2004

[Arthrodesis of the hip and its conversion].

Arthrodesis of the hip used to be an important means of treating painful and damaged hips. Increasing experiences in total hip replacement have led to restrictive indications for arthrodesis and to more and more total hip arthroplasty. Hip arthrodesis has limited indications today. It remains the treatment of choice in deteriorated, painful hip joints, especially in the case of contraindications and severe muscular deficits. The best position of the fused hip is 10 to 25 degrees flexion, 0 to 15 degrees external rotation, 0 to 10 degrees abduction or 0 to 6 degrees adduction. The aim of the operation is a stable osteosynthesis which allows early mobilisation of the patient. Disturbances in walking patterns, mechanical overloading of neighbouring joints, such as the lumbar spine, ipsilateral knee or contralateral hip, often support a conversion from arthrodesis to total hip arthroplasty. The aim of the primary operation, therefore, is the preservation of the stabilizing pelvitrochanteric muscles and their insertions.

Arthrodesis↗

PubMed2004

[Femoral nerve palsy due to excessive granuloma in aseptic cup loosening in cementless total hip arthroplasty].

AIM: Femoral nerve palsy after total hip arthroplasty can result from several causes. Delayed neuropathies of the femoral nerve because of excessive granuloma in loosened implants are a rare condition. CASE REPORT: We report the case of delayed neuropathy of the femoral nerve after cementless total hip arthroplasty because of aseptic loosening of the cup. Electrophysiologic evaluation revealed a severe lesion of the femoral nerve with sensomotoric deficits. An abdominopelvic computed tomography (CT) scan revealed an excessive granuloma with a large intrapelvic portion. After revision of the loosened acetabular component and the femoral nerve and removal of the granuloma the neurologic symptoms improved. CONCLUSION: Regular (1-2 years) clinical and radiological follow-ups are requested after total hip arthroplasty to prevent excessive loosening of implants, excessive granuloma and severe sequelae like nerve damage.

Arthroplasty, Replacement, Hip↗

PubMed2004

[Surface characterisation of shot peened implants with glas beads in total hip arthroplasty].

UNLABELLED: Alumina-blasting is used to create a rougher surface of Titanium implants in cementless total hip arthroplasty to achieve a better bony ingrowth. An increasing number of publications in maxillofacial surgery and orthopaedic surgery show that there is a significant contamination in Alumina blasted surfaces. Latest research published an effect of contaminant particles on early loosening of endoprostheses associated with third body wear. Due to our knowledge no previous study analysed surface contamination of hip endoprostheses with glass beads. Aim of our work was to evaluate the percentage of contaminated surface of hip endoprostheses with glass beads. MATERIAL AND METHOD: The surface of 5 Ti-VPS sprayed Phoenix cups and 5 morse-taper-junctions of the MRP-Titan revision stem (Peter Brehm, Chirurgie Mechanik, Weisendorf) were analysed with respect to glass particles. Shot peening was performed with glass beads "BALLOTINI" MGL, Fa. Würth Strahlmittel. A field emission scanning electron microscopy (LEO 1525) was used for the detection of the glass-particles on the implant surface with a backscattered electron detector. The particle covering position was calculated by means of an imaging analyze software (analySIS, Soft Imaging System GmbH). RESULTS: The surface of the Ti-VPS sprayed Phoenix cups showed a contaminated area at a mean of 9.2 +/- 1.3 %, morse-taper-junctions of the MRP-Titan stem at a mean of 9.6 +/- 2.1 % with glass particle contact. DISCUSSION: The results of this study clearly show that there is a contamination of shot pinned Titanium surfaces with glass particles in a significant percentage. With respect to third body wear in total hip arthroplasty further studies are necessary to minimize contamination.

Equipment Contamination↗

PubMed2004

[Results of fixation of osteochondral lesions of the talus using K-wires].

INTRODUCTION: Etiology of osteochondral lesions of the talus remains uncertain, a myriad of treatment options exists. The purpose of this study is to evaluate the clinical and radiological results of fixation of osteochondral lesions of the talus using K-wires. An unstable osteochondral fragment or osteosclerotic changes in the bed of the talus were regarded as indications for the procedure. PATIENTS AND METHOD: We report a retrospective study of 20 patients who underwent fixation of osteochondritis dissecans of the talus between 1.1.1995 and 31.12.2000. There were 14 men and 6 women. The average age was 18 years (range, 11 to 52 years). The average duration of symptoms prior to surgery was 30 weeks (range, 8 to 100 weeks). RESULTS: The average duration of follow-up was 46 months (range, 18 to 93 months). The overall clinical result was rated good in 4 cases and excellent in 16 cases according to the Ogilvie-Harris score. There were no surgical complications. All osteochondral lesions healed. CONCLUSION: Using K-wires for fixation of osteochondral lesions of the talus repair of the articular surface and stability of the lesion can be achieved even in unstable chronic lesions.

Adolescent↗

PubMed2004

[The modular hip revision stem made of titanium alloy--influence and optimisation of bending stiffness].

UNLABELLED: The MRP-Titan Revision stem has proved to be a highly successful implant system for revision arthroplasty of the hip. Good and excellent clinical and radiological results with spontaneous filling of bony defects have been reported, The observation of atrophy of the proximal femur associated with stem diameters > 17mm prompted us to examine the bending stiffness of stems of various diameters. To determine their static bending characteristics, the stems were tested under axial pressure loads in accordance with Euler's buckling case. Dynamic tests were performed with the mono-axial servohydraulic test equipment MTS 810. From a stem diameter of 18 mm upwards, deflection of the stem under loading decreased disproportionately, in direct correlation with the stem stiffness. By optimising the geometry and varying the alloy it is possible to obtain a constant ISD factor for the modular MRP-Titan revision stem CONCLUSION: The MRP-Titan revision stem is a reliable implant system for revision arthroplasty of the hip. Clinical findings of atrophy of the proximal femur associated with stem diameters > 17 mm was found to be correlated with a disproportionate increase in bending stiffness. The aim of further developments will be to reduce the stiffness of larger-diameter stems by making changes to the design and/or to the alloy (Ti15Mo, Ti13Nb13Zr, Ti12Mo6Zr2Fe2).

Compressive Strength↗

PubMed2003

[Septic loosening of a Wagner revision stem provoked by Mycobacterium tuberculosis].

Only a few cases of specific tuberculous infections of total hip arthroplasties have been published. We report the case of a 66-year-old male patient who received a cementless total hip arthroplasty due to osteoarthritis of the left hip in 1990. Four years later, revision arthroplasty with a Wagner revision stem was performed because of aseptic loosening. In 1995 revision of a loosened acetabular cup was necessary. In 1996 we saw the patient for the first time in our outpatient unit. He complained of increasing pain in the region of the left hip. X-rays showed loosening of the Wagner stem. Aspiration of the synovial fluid of the left hip revealed an infection with mycobacterium tuberculosis (radioimmunoassay). There were no signs of tuberculous infection in the patient's history. Treatment consisted of removal of the prosthesis followed by antituberculosis chemotherapy for 12 months with rifampicin, ethambutol, isoniazid, and pyrazinamide. In April 2001 revision of the left hip joint and implantation of a MRP titanium revision stem and reconstruction of the acetabulum with an acetabular reconstruction ring was done. Until today the patient exhibits no signs of recurrence of the tuberculous infection.

Acetabulum↗

PubMed2003

[Rupture of the gluteus medius tendon].

AIM: Rupture of the gluteus medius tendon is a rare, even neglected condition. Typical findings include local tenderness and weakness of hip abduction. This pathologic condition is very seldom analysed in the literature, there is no report about the meaning in primary total hip replacement (THR). PATIENTS: Between 1/1/1995 and 12/31/2000 we found 13 cases (3,5 %) with a tear of the gluteus medius tendon in 372 primary THR using the lateral approach. In all cases the rupture was seen in the ventral and lateral part of the gluteus medius tendon. Furthermore, a valgus position of the proximal femur was detected. Transosseous refixation of the tendons was performed in all cases. 3 months after operation local tenderness near the greater trochanter disappeared and full strength of the pelvitrochanteric muscles was achieved in 11 out of 13 cases and in the remaining cases after one year. CONCLUSION: When a valgus position of the proximal femur in primary THR is found, one has to be aware of a simultaneous rupture of the gluteus medius tendon. This pathologic finding has to be ruled out preoperatively by means of ultrasound or MRI and an adequate approach to the hip joint has to be selected to examine the pelvitrochanteric muscles and to treat the rupture.

Aged↗