Biomedical subjects
Publications and source records attributed to G Zannini.
The authors have tried to show the close link between the lymphatic and venous systems. They describe the clinical aspects which cause us to note that one or other of these systems is the more affected, and they bring to mind aetiological theories on the origin, either congenital or acquired, of the affection. This leads to considerations clarifying the clinical and anatomo-pathological data.
Diagnostic laparotomy with splenectomy was performed in 188 patients with Hodgkin's disease. Preoperative assessment by means of conventional methods of examination was confirmed in 118 cases (62.9%) and had to be modified in the remainder. Post-operative complications were observed in 12 cases (6.5%). One subject died of myocardial infarct. It is felt that the procedure is useful in establishing the stage of the disease and in planning treatment. It must not be applied indiscriminately, however, and is primarily useful insofar as it results in a modification of the therapeutic programme.
Although prehepatic portal hypertension (PHPH) is less common than intrahepatic portal hypertension, it gives rise to more serious diagnostic and therapeutic problems than the latter. From their experience of 88 cases, the authors feel that it is necessary for a correct approach to PHPH to derive a classification useful throughout the clinical course of these patients. They distinguish PHPH due to extrinsic obstruction from PHPH due to intrinsic obstruction, and subdivide these two classes according to etiologic, pathologic and hemodynamic criteria. A series of principles has been developed, in answer to the problems related to each of these classes, as an aid in the prevention of portal hypertension relapse.
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The authors attempt to explain why oedema forms following operation, referring to an experiment of 900 cases of patients suffering from acute or chronic ischemia treated by surgery. They look for reasons for this oedema and suggest that the origin, in a large number of cases, is lymphatic.