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Biomedical subjects

G Zamboni

Publications and source records attributed to G Zamboni.

At least 199 records · Page 11Linked to original sources
PubMed1977

Absence of thermoregulatory vasomotor responses during fast wave sleep in cats.

The skin temperature of the pinna was recorded in unrestrained cats sleeping at different ambient temperatures. The results show that during fast wave sleep vasomotion is inconsistent with homeothermic regulation as ear skin temperature increases and decreases at low and high ambient temperatures, respectively. The effects of preoptic heating during slow wave and fast wave sleep reveal that a depression of the responsiveness of hypothalamic thermoceptive structures underlies the absence of thermoregulatory vasomotor responses during fast wave sleep.

Animals↗
PubMed1977

Association of osteopetrosis and vitamin D-resistant rickets.

The following report concerns a case of malignant osteopetrosis associated with hypocalcemic rickets unresponsive to vitamin D. Parathyroid hormone (PTH) and Calcitonin (CT) secretions were studied in basal conditions and under calcium gluconate infusion, before and after high doses of vitamin D. Basal values (PTH: 690 pg Eq/ml; CT: 560 pg/ml) were found to be much higher than in five control subjects of the same age group, even after vitamin D therapy (PTH: 990 pg Eq/ml; CT:450 pg/ml). Like rickets, PTH and CT secretions do not seem, therefore, to be notably influenced by vitamin D therapy.

Calcitonin↗
PubMed1975

Hypothalamic temperature during the sleep cycle at different ambient temperatures.

Hypothalamic temperature during complete and incomplete sleep cycles (slow wave sleep followed by fast wave sleep and slow wave sleep followed by arousal, respectively) has been studied in freely moving cats at 20 degrees C and 0 degrees C ambient temperatures. The results show that sleep and thermoregulatory processes interact and, at 0 degrees C ambient temperature, become mutally exclusive. The occurrence of fast wave sleep is related to an opptimum range of hypothalamic temperatures which is specific in each enviromental conditions.

Animals↗
PubMedDate not supplied

Ultrasonography of the pancreas. 4. Contrast-enhanced imaging.

The introduction of contrast-enhanced ultrasonography (CEUS) has lead to great developments in the diagnostic capabilities of ultrasound. Second generation contrast media, characterized by harmonic responses at low mechanical index of the ultrasound beam, have already proven usefulness in the study of the liver but other abdominal organs can take advantage from the dynamic study during continuous ultrasonographic scans. The dynamic observation of the enhancement allows the perfect evaluation of the abdominal organs perfusion. The perfusion of the pancreas is well correlated to the semeiology of the gland parenchymography at CEUS. The study of the pancreas is a new and promising application of CEUS. CEUS can be used to better identify pancreatic lesions respect to conventional Ultrasound (US) or to characterize pancreatic lesions already visible at US. Moreover the staging of some pancreatic lesions can be improved by the use of contrast media. This article will review the clinical application of CEUS in the different pancreatic pathologies.

Contrast Media↗
PubMedDate not supplied

Ultrasonography of the pancreas. 5. Interventional procedures.

Interventional ultrasonography (US) is often used for the diagnosis and therapy of pancreatic pathologies, and its diffusion has definitely modified the diagnostic and therapeutic management of some diseases. US is particularly suitable for targeting percutaneous pancreatic interventional procedures and important technical features contribute to this result. First of all, US is dynamic, and thus the ongoing procedure can be continually monitored. Then, the high spatial resolution achieved by US imaging in recent years, its speed and availability and the low-cost of the technique, together with the technical features, have led to an ever-increasing use of US in pancreatic interventional procedures. This article will review the application of US as guide of diagnostic and interventional procedures in the different pancreatic pathologies.

Biopsy, Needle↗
PubMedDate not supplied

Recombinant human growth hormone replacement therapy and bone metabolism in children.

Growth hormone (GH) influences not only skeletal growth and maturation but also bone turnover and mineral deposition. The effect on bone mineral status of 2 different regimens of rhGH therapy was evaluated in 22 children with idiopathic GH deficiency (GHD) - age 5-8 yrs; bone age 3-5 yrs. Ten of them (group 1) were treated 3 times a week with rhGH, administered subcutaneously, for a total weekly dose of 0.5 IU/kg and 12 (group 2) with the same weekly dose 6 times per week. Insulin-like growth factor 1 (IGF-1) and osteocalcin (OC) levels increased in both groups after therapy but they were higher in group 2. In basal conditions bone mineral content (BMC) and BMC/bone width ratio (determined by dual image-assisted photon absorptiometry) were significantly lower in patients than in controls and significantly increased after 6 months of rhGH therapy only in patients of group 2. rhGH administered 3 times a week increased IGF-1 and OC levels, indicating that turnover and remodeling processes of the bone had started, but the same dose had to be given every day to lead to calcium deposition in the bones. Probably a continuous supply of rhGH better optimizes the body utilization of the hormone, as indicated by better height velocity and bone density in patients of group 2. The response to an acute load of 1,25(OH)2D3 (1.5 micrograms/day for 4 days), both before and after a month of rhGH therapy (weekly dose of 0.5 IU/kg 6 times were week), was evaluated in 16 children with GHD - age 6-9 yrs.(ABSTRACT TRUNCATED AT 250 WORDS)

Absorptiometry, Photon↗
PubMedDate not supplied

Extracellular matrix of small round cell tumors of childhood: an immunohistochemical study of 67 cases.

Sixty-seven childhood tumors were studied immunohistochemically for the extracellular matrix element type IV collagen, laminin, and fibronectin. Tumors included Ewing's sarcoma, primitive neuroectodermal tumor, small cell osteosarcoma, neuroblastoma or ganglioneuroblastoma, rhabdomyosarcoma, and lymphoma. It was found that small cell osteosarcoma was often positive for fibronectin but not type IV collagen or laminin, a new observation. In the lymphomas, matrix proteins were rarely found. Ewing's sarcoma was variably positive for type IV collagen and laminin, but fibronectin was absent. Extracellular laminin and fibronectin were found in one of two cases of primitive neuroectodermal tumor. In neuroblastoma and ganglioneuroblastoma, the matrix components were rarely found. These results, discrepant with findings in cultured cells, may reflect the altered capacity of tumors to produce these proteins in vitro, which suggests that caution should be exercised in drawing conclusions regarding the nature or histogenesis of tumors from data obtained with cultured tumor cells. Embryonal rhabdomyosarcoma frequently contained all matrix elements in the extracellular space and in a dotlike pattern in the cytoplasm; alveolar rhabdomyosarcoma rarely contained these proteins and never exhibited the dotlike pattern. The frequent finding of matrix proteins in embryonal rhabdomyosarcoma but only rarely in alveolar rhabdomyosarcoma and the unique immunostaining pattern in embryonal rhabdomyosarcoma may prove to be a useful adjunct in the diagnosis of childhood tumors.

Adolescent↗