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Biomedical subjects

G Witte

Publications and source records attributed to G Witte.

At least 19 recordsLinked to original sources
PubMed1992

[Superselective interventional angiography].

The authors report on the clinical application of superselective interventional angiography within the framework of revascularisation and occlusion. A coaxial catheter system is used for probing, consisting of an F 5 angiography catheter as guiding catheter and an F 3 catheter as internal catheter. The internal catheter is equipped with a shaft with segments of different flexibility and can take up a guide wire of 0.018" that is sufficiently stable to be rotated and guided. The interplay between the guide wire, which can be manipulated, and the flexible internal catheter enables superselective probing even of peripheral vascular areas. As may be required by the basic disease, the necessary interventional measures can be taken via the superselectively placed microcatheter. Superselective interventional angiography is indicated as an occlusive measure in preoperative vascular occlusion followed by palliative tumour resection, embolisation in haemangioma, chemoembolization in tumours of the liver. Superselective angiography is used for revascularisation in the local lysis of peripheral vessels. Due to the on-target superselective approach, side effects are markedly less than those observed with the interventions performed to date.

Angiography↗
PubMed1992

[Results of CT-controlled puncture of the thorax].

Results of 56 CT-guided biopsies in 45 patients are presented. Aspiration biopsies (n = 23) had a usable result in 75% of the cases; cutting biopsies (n = 33) in 80%. The main complication was the pneumothorax with 9%; in one patient the procedure caused a haemoptoe.

Humans↗
PubMed1992

[Results of CT-guided puncture biopsies in the abdominal and pelvic regions].

Results of 285 abdominal and pelvic CT-monitored biopsies are presented. 81.6% of the histological biopsies (n = 46) were evaluable (39.1% right positive, 43.5% right negative, 4.35% suspect). In 13% no definite findings were made. For the cytologic examinations and those due to an abscess 44.8% led to a right positive diagnosis and 23.8% gave a true negative finding. In 4.2% of the cases a suspect finding was given. 28% of all cytological evaluations were not definite. The complication rate was 1%.

Adolescent↗
PubMed1991

[Chemoembolization in primary hepatocellular carcinoma].

The only generally recognised form of treatment for primary liver cell carcinomas is partial liver resection; occasionally this may be curative. This form of treatment is only applicable in 5% to 30% of patients. All drug-based forms of treatment have proved of little value. The new interventional radiological method of chemo-embolisation has shown results in improving survival rates which are comparable with resection. By using a new coaxial catheter system, embolisation can be performed as a selective intrahepatic procedure; it has few side effects and the quality of life subsequently does not deteriorate.

Carcinoma, Hepatocellular↗
PubMed1991

Intestinal absorption of aluminium: studies in the isolated perfused rat intestinal preparation.

Aluminium (Al) absorption was studied using an isolated in vitro vascularly perfused rat intestinal preparation. Al was introduced into the lumen as AlCl3, Al(NO3)3 or Al lactate to give final concentrations equivalent to 0.625, 1.25, 2.50, 5.00, or 10.00 g/L of Al. The intestinal tissue remained viable up to 5.0 g/L of Al. The amount of Al associated with intestinal tissue after 90 min increased with the concentration up to 5 g/L of Al for chloride and nitrate and 10 g/L of Al for lactate. The time course of Al disappearance from the lumen followed a single exponential decay when the intestinal lumen was perfused with 0.625 g/L of Al as the chloride salt. The total amount of Al appearing in the vascular perfusate after 90 min was always small. Absorption quotes ranged between 0.005-3.2% depending on the salt and concentration used. Addition of transferrin to the VM caused a 2-fold increase in the amount of Al appearing in the vascular effluent in comparison with controls when 1.25 g/L of Al as AlCl3 was introduced into the lumen. Al tissue content was not affected.

Aluminum↗
PubMed1990

[A comparison of digital luminescence radiography and the conventional film-screen technic in pulmonary coin lesions--a clinical study].

The aim of this investigation is the evaluation of DLR for the radiological diagnosis of intrapulmonary coin lesions. For this, a DLR system was used which had been specially developed for chest radiography. Early results were unsatisfactory and therefore specific image parameters were developed. The scope for dose reduction was also investigated. Oncology patients were examined by DLR and by our reference system. Results show that DLR is better than conventional images if edge enhancement is carried out, using the specific parameters. The superiority of the optimised digital images is apparent particularly in those portions of the lung that are obscured by the cardiac or diaphragmatic shadows. Because of image noise, a dose reduction of only 28% is possible, compared with our reference system.

Evaluation Studies as Topic↗
PubMed1990

[Clinical and technical experiences with digital luminescent radiography in phlebography of the leg].

Digital luminescence radiography is being increasingly integrated into clinical routine work and is fundamentally suited to replace x-ray film/screen takes. After the necessary optimization of the specific image processing procedure we examined the diagnostic efficacy of this method in respect of phlebography of the leg. If the radiation dose was reduced by 47% in relation to the reference system, the usefulness of the findings in arriving at the diagnosis was by no means reduced under the conditions of high contrast that apply in phlebography, but there was also no additional advantage in respect of diagnostic accuracy. The technical advantages concern mainly the absence of wrong exposures, the possibility of subsequent processing of the image to improve the image quality, and digital storage.

Evaluation Studies as Topic↗
PubMed1990

[The lateral thoracic radiograph in the intensive care unit using digital luminescence radiography].

The digital luminescence radiography (DLR) technique is being used increasingly for clinical diagnosis, particularly in intensive care . Since the installation of a DLR unit, we have carried out more than 20,000 examinations of the chest on patients in intensive care. 12.1% of these were lateral radiographs. In this way, the diagnosis can be made of the extent of a pleural effusion, the presence of a ventral pneumothorax or of atelectasis. Using DLR, these examinations can be carried out at the bedside and have improved the radiological investigation of patients in intensive care.

Humans↗
PubMed1990

[Partial resection of primary liver cell cancer].

Between 1985 and 1990, 47 patients with primary hepatocellular carcinoma (HCC) underwent surgery (n = 27), chemoembolization (n = 12) or palliative resection followed by chemoembolization (n = 5). In 85% of the patients a T3/T4 tumor stage was found, 68% had liver cirrhosis and 42% were older than 70. Mortality was 18.7% after liver resection and 0% after chemoembolization or combined treatment. Average survival was 4.4 months after chemoembolization, 11.6 months after resection and 11.6 months after palliative resection of the HCC followed by chemoembolization with angiostat/adriblastin.

Aged↗