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G Wilk

Publications and source records attributed to G Wilk.

32 records · Page 2Linked to original sources

[Conditions affecting the renal excretion of manganese by humans (author's transl)].

The renal excretion of manganese is investigated for different urine flow rates in adults of both sexes with normal and disturbed kidney function. Mn is determined by emission spectral analysis. During antidiuresis with a mean urine flow rate of 0,97 +/- 0,66 ml/min (SD) the average excretion of Mn is 11,4 +/- 19,4 ng/min for 1,73 m2 body surface area. With an indifferent urine flow (4,43 +/- 2,11 ml/min) the average Mn excretion is 13,5 +/- 19,3 ng/min. For this type of diuresis Mn excretion and urine flow rate are slightly positively correlated. A further increase in urinary excretion of Mn is observed during osmotic diuresis. In this case 160,6 +/- 180,5 ng Mn/min are eliminated for an urine production of 22,2 +/- 6,8 ml/min. The difference of the mean excretion values is highly significant (P less than 0,01) between indifferent urine flow and osmotic diuresis, insignificant between antidiuresis and indifferent urine flow, and significant (P less than 0,01) between antidiuresis and osmotic diuresis. Down to a clearance value for inulin of less than 30 ml/min and for PAH of less than 200 ml/min and 1,73 m2 body surface area, the Mn excretion is largely independent of the renal hemodynamics.

Adolescent↗

[Conditions affecting renal excretion of silver by humans. Studies on metabolism of trace elements. VIII].

The renal excretion of silver was investigated in adult experimental persons of both sexes with normal or variously decreased kidney functions. Silver was measured by emission spectrum analysis. With an indifferent urinary flow of 4.71 plus or minus 2.5 (mean value with standard deviation) ml/min, the mean Ag-excretion was 0.653 plus or minus 0.432 ng/min for a standard 1.73 m2 body surface area. An apparent small increase in the Ag-excretion with increased rate of urine flow could not be statistically confirmed. The widely different Ag-excretion between individuals showed no dependence on the state of diuresis, or on kidney haemodynamic factors down to a decreased inulin clearance of less than 40 ml/min, and a decrease of the PAH clearance to values less than 200 ml/min.

Adolescent↗