Biomedical subjects

G Wedekind

Publications and source records attributed to G Wedekind.

5 recordsLinked to original sources

PubMed1998

[Single shot MRI cholangiopancreatography (MRCP) with a "fast acquisition spin echo" sequence (FASE). Replacement of ERCP?].

PURPOSE: 118 Patients with suspected obstruction of the biliary tract of pancreatic duct were examined to evaluate the accuracy of MR cholangiopancreatography (MRCP) in comparison with diagnostic findings in endoscopic retrograde cholangiopancreatography (ERCP). METHODS: Using a 0.5-Tesla MR imaging system (FLEXART, Toshiba) and a QD body-coil, a recently developed heavily T2-weighted fast acquisition spin echo sequence (FASE) was applied. In this FASE sequence two significant features are implemented. A fast spin-echo (SE) sequence allows a large number of echos and conjugate K-space filling speeds up data acquisition. Thus, the acquisition time of single-shot breath-hold images takes only 3 seconds, which makes MRCP a feasible technique even in elderly or suffering patients. There is no need for time-consuming postprocessing procedures. RESULTS: In all MRCP examinations images of satisfactory quality were obtained. In cases of obstruction of the biliary or pancreatic duct, locations and lengths of stenoses were correctly demonstrated. Gallstones within the gallbladder or in the extrahepatic bile ducts were also properly visualised in MRCP. Stenoses caused by non-depicted pancreatic carcinoma, gallbladder carcinoma, or segmental pancreatitis were reliably shown. CONCLUSION: Even if MRCP will not replace ERCP, a number of clinical applications for non-invasive MRCP examination arise: primary diagnosis in patients with obstructive jaundice, obstruction of the biliary or pancreatic duct, if ERCP is not possible due to anatomic reason and in patients scheduled for laparoscopic cholecystectomy.

Adult↗

PubMed1995

Significance of radiological diagnosis for detection and staging of inflammatory abdominal aortic aneurysm.

Operative morbidity and mortality are elevated in patients with inflammatory abdominal aortic aneurysm. Preoperative identification of inflammatory abdominal aortic aneurysm. the detection of the proximal level and of adhesions to adjacent structures are important for surgical management. The sensitivity and specificity of ultrasonography and computed tomography (CT) for identification and staging in 13 patients with inflammatory abdominal aortic aneurysm were studied. Preoperative radiological diagnoses were validated by intraoperative findings. Correct identification of inflammatory abdominal aortic aneurysm could be achieved in 85% by the use of CT and in 62% by ultrasonography. The proximal level of inflammatory abdominal aortic aneurysm was correctly determined by CT in all patients and by ultrasonography in 62%. Using a transperitoneal approach, the condition was considered inoperable in two patients as a result of the suprarenal extent of the aneurysm and because of unremovable adhesions in two other cases. In the latter pair, it was impossible to predict inoperability by radiological findings. Sensitivity (85%) and specificity (100%) of standard radiological techniques to identify inflammatory changes are high. Inoperability caused by suprarenal extent could be detected correctly by routine radiological procedures. However, identification of dense adhesions appears uncertain.

Adult↗

PubMed1994

[Multiple microembolization caused by elemental mercury].

Elemental mercury is usually found in the vascular system following intravenous injection. It is distributed in the body in two different ways, which are described in detail. We report the case of a 39-year-old male, who injected elemental mercury in his cubital vein in a suicide attempt. This fact was detected accidentally during clinical treatment. Microemboli of metallic mercury were found in the lungs, liver, spleen, kidneys, central nervous system and other organs. A high serum concentration of dissolved and oxidized mercury was detected. No signs of chronic mercury intoxication in the form an organic functional disturbance were obvious.

Adult↗

PubMed1992

[Retractile mesenteritis].

We report the case of a 76-year-old patient with cachexia, abdominal pain and anemia who was referred for computed tomography to exclude the possibility of a malignoma. We diagnosed retractile mesenteritis, which was verified by laparoscopy with exploratory excision and histological examination. Exploratory laparatomy, recommended even today, could be prevented. In this procedure, extensive parts of the mesenterium and intestine are often resected because of the possibility of a tumor. After therapy with prednisone, there was clinical recovery and the symptoms regressed, as shown by computed tomography.

Aged↗

PubMed1991

[Mesenteric panniculitis].

In a 76 year old patient computed tomography of the abdomen and laparoscopic biopsy revealed a mesenteric panniculitis as cause of recurrent fever and shaking chills. The fever resolved under corticosteroid therapy and the patient remains well three month after onset of treatment.

Aged↗