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Biomedical subjects

G W Timm

Publications and source records attributed to G W Timm.

At least 19 recordsLinked to original sources
PubMed1977

Auscultation of urinary flow.

Urinary flow in the male subject is associated with turbulence at the bladder neck. This turbulence is associated with the production of a sound in the healthy male subject, transmitted to the perineum.

Auscultation↗
PubMed1976

Cystometry. VI. Interpretation.

Cystometry should be performed under direct supervision of a physician, and interpretation must be supplemented by additional test procedures.

Female↗
PubMed1976

Neurology of micturition.

The understanding, diagnosis and management of neurologic dysfunction of the bladder have undergone considerable changes during the last 2 decades. These changes were the result of animal experimentation into physiology and pharmacology and the accelerated use of biomedical engineering technology. The implementation of these advances will require physician re-education in the neurology of micturition.

Electric Stimulation↗
PubMed1976

The urethral electromyographic and gas pressure profile. Technique and patterns.

A new technique for recording of the urethral pressure profile is described. The technique consists of a combined electromyographic and gas urethral pressure profile recording. Normal and pathological patterns are described. The method provides information of the correlation between intra-urethral pressure and activity in the periurethral striated musculature, and has proved useful in the assessment of neurological dysfunction of the urethra.

Electromyography↗
PubMed1976

Electrophysiological techniques for the study of urethral and vesical innervation.

A new electrophysiological technique for the study of urethral and vesical innervation is reported. The method gives valuable information on the structural integrity and function of two of the reflex arcs involved in micturition. Normal and pathological patterns are described, illustrating the diagnostic value of the method in the assessment of neurogenic disturbances of bladder and urethral function.

Anal Canal↗
PubMed1976

Electrophysiological technique for evaluating lesions of the conus medullaris and cauda equina.

The authors describe the use of evoked electromyographic responses recorded in the anal sphincter induced by stimulation of the bladder wall and urethra in evaluating lesions of the conus medullaris and cauda equina in 110 patients. This reflex response took effect by way of the pelvic nerves and cauda equina to the sacral cord where the pudendal nerve nucleus was activated, resulting in a contraction of the external anal sphincter. Various lesions along this pathway have been shown to produce either increased latencies and depressed responses or complete loss of response depending on the extent of the lesion. The correlation of results of this technique with clinical, myelographic, and operative findings indicate it to be a useful clinical tool.

Anal Canal↗
PubMed1976

Some contractile and electrophysiologic properties of the periurethral striated muscle of the cat.

Evidence for differences between the periurethral striated muscle and external anal sphincter of the cat is provided by measurement of the contractile properties in situ and in vitro and the electrophysiologic properties in vitro. In the periurethral striated muscle, the contractile pressure response was faster, d-tubocurarine sensitivity was greater, d-tubocurarine blockade had a shorter duration, and fatigue was faster but not uniquely fast as compared with results for the external anal sphincter. These results suggest that the periurethral striated muscle has similar characteristics to certain fast twitch muscles. Effect of succinylcholine on the periurethral striated muscle and external anal sphincter was similar. Miniature end-plate potentials had large amplitudes which appeared to be correlated to the small diameter of the periurethral striated muscle fibers. Since only focally distributed miniature end-plate potentials could be found, true physiologically slow muscle fibers were absent.

Anal Canal↗
PubMed1976

Genitourinary prosthetics of the present and future.

Development of implantable prosthetic devices to restore genitourinary function has evolved from applying electrical stimulation techniques for bladder evaluation to adapting fluid energy transfer system for occlusion of the urethra to increase outlet resistance. These hydraulic prostheses have been implanted in several hundred patients in medical centers around the world. The principles behind the operation of this closed-loop system, an some alternative designs that simplify the implant procedure, are described here.

Humans↗
PubMed1976

[Development of an implantable artificial urinary sphincter (author's transl)].

Fifteen years experience with investigations of the neurologic aspects of lower urinary tract function has produced a therapeutic rationale that includes utilization of prosthetic devices in selected patients. Development of an implantable artificial sphincter evolved as a necessity for restoring urinary continence became apparent. The experimental design of animal models and the technologic methods in device development are herein described.

Animals↗
PubMed1975

Cystometry. (2). Central nervous system organization of detrusor reflex.

Micturition is a brain stem reflex dependent on the integrity of reticulospinal and sensory pathways in a manner similar to respiration and blood pressure regulation. The detrusor reflex which is evoked by bladder distention and may appear in the normal cystometrogram is a result of the integrity of the circuit. Interruption of the spinal cord pathways of this loop by trauma or by spinal cord tumors results in abolition of detrusor reflex. Partial interruption results in an uninhibited detrusor reflex.

Brain Stem↗
PubMed1975

Cystometry: III. Cystometers.

Cystometers may employ either fluid (water) or gas (air or carbon dioxide) as the distending medium. The operation of air and carbon dioxide cystometers is described, and a comparison is given of the various systems currently in use.

Air↗
PubMed1975

Cystometry. V. Bladder sensation.

Bladder sensation is an important variable in cystometry. Sensory complaints are a valuable portion of the history which may be further defined and documented by the cystometric examination.

Animals↗