Biomedical subjects

G W Machiedo

Publications and source records attributed to G W Machiedo.

70 records · Page 4Linked to original sources

PubMed1977

Giant recurrent desmoid tumor: a case report.

A case of giant recurrent intra-abdominal desmoid tumor is presented. A history of childbirth, antecedent surgery, multiple episodes of recurrence, resistance to excisional and radiation therapy, represent common features of desmoid tumors. The size of the recurrence (15.4 kg), the intra-abdominal presentation of the tumor, involvement of the chest wall and focal infiltration of the small bowel are unusual features of this case.

Abdominal Neoplasms↗

PubMed1976

Functional longevity of intraperioneal drains: an experimental evaluation.

Various types of drains were inserted into the peritoneal cavity of twenty-eight dogs. After one to seven days, all drains failed to show the presence of 200 cc of colored fluid injected intraperitoneally. On autopsy, all tubes were surrounded and occluded by omentum.

Animals↗

PubMed1976

Beneficial effect of prostaglandin E1 in experimental hemorrhagic shock.

Twelve dogs were subjected to hemorrhagic shock by means of a modified Wiggers technique. Half were treated with prostaglandin E1, 1 microgram per kilogram per minute in 60 milliliters of saline solution, for one hour after shock, while the other half received only an equal amount of saline solution. Those dogs treated with prostaglandin E1 exhibited a significantly increased survival time and cardiac output as well as a significantly lowered total peripheral resistance when compared with those for untreated dogs. The various modes of action by which prostaglandin E1 exerts both its cardiovascular and other long term effects indicate a multisystem effect of the drug.

Animals↗

PubMed1975

Use of peritoneal lavage in the diagnosis of experimental acute pancreatitis.

Twenty-four dogs were divided into five groups. Under pentothal sodium anesthesia, those in the control group received no further manipulation; another group underwent laparotomy only; and dogs in the last three groups had induced pancreatitis, intestinal ischemia and duodenal perforation, respectively. An analysis was made of serum and peritoneal lavage fluid in the dog of each group at 30 minute intervals for four and one-half hours. Parameters which were significantly elevated in dogs with pancreatitis compared with other groups included fluid amylase, lactate dehydrogenase, proteolytic activity and intestinal alkaline phosphatase and serum amylase. We judge that these biochemical differences in the lavage fluid, when taken with the physical characteristics of the fluid and the clinical symptoms, can significantly aid the clinician in arriving at the diagnosis of acute pancreatitis.

Abdomen↗

PubMed1975