Search PubMed⌕ Search

Biomedical subjects

G W Greene

Publications and source records attributed to G W Greene.

At least 37 records · Page 2Linked to original sources
PubMed1982

The hematopoietic defect of the jaws: a report of sixteen cases.

Biopsy of radiolucent lesions of the jaws has resulted in the identification of areas of hematopoiesis usually designated as focal osteoporotic marrow defects. The majority of the cases reported involve the posterior region of the mandible in a previous extraction site. Pain and swelling are not uncommon. Since the clinical and radiographic symptoms of hematopoietic defects resemble manifestations of other neoplastic and inflammatory diseases, it is important to continue to describe the properties of this interesting entity.

Adult↗
PubMed1981

A critical evaluation of the acute systemic toxicity test for dental alloys using histopathologic criteria.

The A.D.A. acute systemic test for type II, class 11 materials defines compliance on the basis of fewer than 50% mortality at 2 weeks. Histopathologic criteria were developed from pilot study data to evaluate the effects of these materials. In this double blind study, the frequency of histopathological changes in lung, liver, small intestine, and kidney were rated at 2 and 5 weeks, for six dental crown and bridge alloys ranging from 44% to 97% (Au, Pt, and Pd). Two positive 360 mg/kg and 1 g/kg of cadmium and two negative, a blank capsule and untreated control groups were used. There was significant difference (chi square test, X2 = 0.95) between the positive and negative controls at 2 and 5 weeks. The lung, liver, kidney showed the highest level of histopathological changes. Significant changes occurred in the four tissues for all alloys at two and five weeks. At five weeks, alloys with a lower noble metal content (44-62%, Au, Pd, and Pt) elicited significant chronic changes, while higher noble metal content (78-97%) showed healing and no significant difference from the negative controls. Applying histopathologic criteria and statistical parameters independent examiners can examine experimental animals and arrive at conclusive and reproducible results.

Animals↗
PubMed1980

Cryosurgical management of benign and dysplastic intraoral lesions.

Benign and dysplastic diseases of oral mucous membranes commonly present problems in management. The recurrent nature and sometimes widespread involvement of these lesions necessitates a treatment that is easy to use, adaptable to the variations of disease, and relatively free of complications. Cryosurgery meets these treatment requirements admirably. Probe and spray techniques were carefully evaluated in 24 patients. A high rate of cure was achieved by careful attention to adequate freezing of the tissues to lethal temperatures and to follow-up after treatment. Favorable results and high acceptability strongly support more frequent use of this surgical technique in outpatients.

Adult↗
PubMed1979

Benign nerve sheath myxoma: light and electron microscopic features of two cases.

Two new cases of the rare benign nerve sheath myxoma (NSM) are presented. The light microscopic findings are compared with previously reported cases. In addition, the ultrastructural features of three constitutent cell types are described. The lesion is confirmed as a neural sheath neoplasm, and its similarities to other myxomas are discussed.

Adult↗
PubMed1979

Necrotizing sialometaplasia.

Three additional cases of necrotizing sialometaplasia are discussed. Clinical appearance of the lesion is not diagnostic. Microscopy shows pseudoepitheliomatous hyperplasia, squamous metaplasia, and acinar necrosis. No atypia is seen. Mucoepidermoid and squamous cell carcinoma are frequent wrong diagnoses. All reported lesions have healed without recurrence regardless of therapy.

Adult↗
PubMed1978

Squamous-cell carcinoma of the floor of the mouth.

This study was based on the analysis of 100 cases of squamous-cell carcinoma of the floor of the mouth. The male/female ratio was 4.25:1. The peak incidence in women was in the 50 to 59 year age group; in men there was equal frequency in each age group above 50. The five-year survival rate decreased from 86 per cent to 0 as the stage of disease progressed from I to IV. The five-year survival for all stages of disease was 52.7 per cent. Thirty-three per cent developed new primary malignancies; 22 per cent were of the upper alimentary and respiratory tracts. Distant metastases were present in 21 per cent. Fifty per cent were heavy smokers, 33 per cent were heavy drinkers, 28 per cent were both heavy smokers and heavy drinkers, and 21 per cent were nonsmokers and nondrinkers.

Adult↗