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Biomedical subjects

G Venkov

Publications and source records attributed to G Venkov.

5 recordsLinked to original sources

[Diagnosis of penile carcinoma].

UNLABELLED: Diagnosing penile cancer requires a consistent search for initial tumor lesion, determination of the condition of the regional lymph nodes, and a search for distant metastases. Compulsory examinations such as: Inspection, Palpation and Biopsy define the presence of a tumor process and its histological clarification. Additional examinations such as: Echography, Computer tomography, and Magnetic Resonance define the stage of the disease and the method of its treatment. OBJECTIVE: The objective of the present research is to present the diagnostic methods applied in the case of penile cancer at the Clinic of Urology, Medical University-Sofia. METHODS: The patients having penile cancer diagnosis who were treated at the Clinic of Urology, Medical University-Sofia for 13 years, from 1990 to 2002 were studied and 80 cases were found. The diagnostic methods used were examined, and the said methods were conditionally divided into two categories: compulsory and additional. RESULTS: The condition of the palpating inguinal lymph nodes is influenced by the removal of the initial tumor lesion through partial penile amputation and treatment with broad-spectrum antibiotics. The enlarged palpating lymph nodes undergo a process of reverse development in 50% of the cases. CONCLUSIONS: Application of diagnostic methods such as: inspection, palpation, biopsy, echography, computer axis tomography, and nuclear magnetic resonance ensure the diagnosis of the initial tumor lesion in the case of penile cancer. The condition of the palpating inguinal lymph nodes is determined through the above-cited diagnostic methods. The presence of Na metastases in the inguinal lymph nodes is proved through surgical biopsy.

Adult↗

[Verrucous carcinoma of the penis].

OBJECTIVE: The objective of the present retrospective research is to examine cases of verrucous carcinoma of the penis, an uncommon variant of squamous cell carcinoma, as well as to examine the localisation, evolvement and the ways of treatment. METHODS: Patients, treated for carcinoma of the penis at the Clinic of Urology, have been examined for a 13-year interval. From 80 cases of cancer localized in the penis, in only 3 of these verrucous carcinoma has been histologically proved, accounting for 2.4 per cent of the penile cancers. A rare case of a hybrid tumor between verrucous carcinoma and invasive squamous cell carcinoma, which is compared to similar finding as described by other authors. RESULTS: Slow and continuous evolvement of the disease has been observed, which has been followed by periods of aggressive development. The average age of the patients has been specified to be 52.7 years. The tumor has been mainly localized on the surface of the Glans penis. The results have been compared to those described in the literature. CONCLUSION: Wide surgical excision, usually requiring partial or total penectomy, is the treatment of choice. Radiotherapy and chemotherapy have proved to be unsuccessful.

Adult↗

[Echinococcus of the kidney].

Echinococcus of the kidney is a rare form of hydatid disease, and accounts for 2 to 3 per cent of all echinococcoses. Over a ten-year period (1987-1996), eight patients with age ranging from 30 to 61 years are diagnosed and treated. Five of them (62.5 per cent) are discovered in the last two years. In seven instances (87.5 per cent) the diagnosis is made preoperatively on the ground of laboratory examinations; serological tests--intradermal test of Casoni and complement fixation after Ghedini-Weinberg, echographic and roentgenological methods. In two patients (33.3 per cent) scoleces and Echinococcus fragments are discovered in the urine. The serological tests are positive in five cases (62.5 per cent). All patients undergo operation, with nephrectomy performed in five (62.5 per cent), and capsula adiposa renis--in three (37.5 per cent). So far, no relapse of the disease is recorded.

Adult↗