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Biomedical subjects

G Vaillant

Publications and source records attributed to G Vaillant.

At least 55 records · Page 3Linked to original sources
PubMed1987

A social casework contribution to understanding alcoholism.

This article describes a 40-year longitudinal study of alcoholism including the etiology of, progression of, and recovery from the disease. The findings are paralleled with similar studies conducted by social work professionals. The capacity of a longitudinal study to elucidate alcoholism and the recovery process is underscored. The etiological hypothesis that views alcoholism primarily as a symptom of psychological instability is questioned.

Alcoholism↗
PubMed1984

Vulnerability to schizophrenia. Prediction of adult schizophrenia using childhood information.

Forty years ago, Glueck and Glueck studied a group of Boston Inner city children to discover factors relating to delinquency. Detailed information was obtained on 1,000 boys aged 10 to 17 years, 500 "delinquents" and 500 "nondelinquent controls." In follow-up studies of this group, we have found that 24 have a diagnosis of adult schizophrenia. We matched these 24 with 48, who had a nonschizophrenic outcome, on the basis of IQ, ethnicity, age at interview, and original Glueck grouping (delinquent or control). The 72 childhood records were then examined on a blind basis by Independent raters looking for predetermined "indicators of vulnerability to schizophrenia." The total indicator scores were able to differentiate schizophrenic outcome from nonschizophrenic outcome at highly significant levels. A number of the individual indicators were likewise able to predict outcome. Prediction was improved when subjects with the lowest IQs (less than 85) were excluded from consideration.

Adolescent↗
PubMed1982

Hyperinsulinemia associated with normal C-peptide levels in a woman treated with isoniazide.

The authors report on the observation of a woman treated with isoniazide, who presented clinical symptoms of hypoglycemia during treatment (seating, confusion, anxio-depressive syndrome, lipothymia). After the antitubercular treatment was stopped, a moderate hypoglycemia without clinical manifestations accompanied by a marked hyperinsulinemia and normal C-peptide values was detected during a Conn's test. Serum gel filtration on Sephadex G 50 Fine showed that the measured hyperinsulinemia was effectively due to an insulin excess. This excess did not seem caused by surreptitious insulin injection. This seems to be the consequence of a deficiency in insulin catabolism because the C-peptide level was normal. The possible role of isoniazide on carbohydrate metabolism is discussed.

Adult↗
PubMed1980

[Lung hematomas (author's transl)].

The peculiarity of lung hematomas is due to the association of two types of lesions: vascular ruptures and alveolar ruptures. Six original observations are associated to 68 others published by various authors in a detailed general review. The main characteristics are radiological, with the following stages: 1) diffuse confusion giving a widespread picture of a low density and imprecise outline, 2) constituted hematoma with a dense picture with clear cut outline of late diagnosis, 3) less frequently aero-hydric pictures. Evolution takes place by slow spontaneous resorption which does not always require surgery.

Adult↗
PubMed1976

[Association of Kaposi's sarcoma and Hodgkin's disease].

The authors report a new case of the association Hodgkin's disease and Kaposi's sarcoma. A woman of North African origin and suffering from mediastinal Hodgkin's disease developed, after the commencement of polychemotherapy with radiotherapy, Kaposi's cutaneous sarcoma, typical, clinically, histologically and by electron microscopy. In the light of this new case, the authors review 41 cases of the Hodgkin-Kaposi association found in the literature and discuss the inter-relations between Kaposi's sarcoma and diseases of the haemoreticular system, in particular carcinomas, immuno-depressive states (notably in association with renal transplants) and virus disorders (essentially herpes). It might be possible to incriminate in the aetiology of Kaposi's disease a carcinogenetic process of viral origin during a state of immuno-depression.

Adult↗
PubMed1975

[A case of parieto-pulmonary acquired shunt presenting with hemoptysis (author's transl)].

The authors report the case of a 52 year old man with arteriovenous shunt developing from the 7th left intercostal artery, revealed by hemoptysis and proved by intercostal selective arteriography. The patient had a past history of serofibrinous pleurity 29 years previously and had undergone paracentesis at this level. The origin of this shunt is then discussed.

Angiography↗