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Biomedical subjects

G Unge

Publications and source records attributed to G Unge.

At least 55 records · Page 3Linked to original sources
PubMed1977

Capillary proliferative activity in myocardium and skeletal muscle of exercised rats.

The capillary proliferative activity in heart and skeletal muscle was studied by autoradiography after in vivo injections of [3H]thymidine in swimming exercised rats. Swimming exercise led to hypertrophy of the myocardium and the muscle fibers of the fore- and hindlimbs. When compared with normal controls a highly significant increase in nuclear incorporation of [3H]thymidine was found in the cells of the myocardial capillary walls. No increased incorporation of [3H]thymidine was found in capillary wall cells of fore- and hindlimb muscles. The findings confirm previous observations of a significant neoformation of myocardial capillary blood vessels in swimming-induced cardiac hypertrophy, whereas any capillary neoformation in the hypertrophying skeletal muscles of this experimental model is insignificant.

Animals↗
PubMed1976

Formation of coronary arterial thrombi in relation to onset of necrosis in acute myocardial infarction in man. A clinical and autoradiographic study.

The presence of radioactivity in coronary arterial thrombi was studied at necropsy by autoradiography in 12 patients with acute myocardial infarction. Seven patients had been given 125I-and five patients 131I-labeled fibrinogen. With a short interval (less than 10 hours) between onset of symptoms and injection of fibrinogen the entire thrombus was radioactive in four of five patients, whereas with longer time intervals only parts or none of the thrombus contained detectable radioactivity. The findings give further evidence that thrombus formation in acute myocardial infarction probably is a slow process and that the major part of the thrombus may form after the onset of necrosis.

Aged↗
PubMed1976

The myocardial capillary vasculature in exercising animals with increased cardiac pressure load.

The myocardial capillary reaction was studied in normal rats subjected to swimming exercise and in rats in which aortic stenosis had been produced at various time intervals before the swimming exercise was commenced. The data obtained indicated that neoformation of myocardial capillaries during swimming exercise occurred only in rats without aortic stenosis. It is concluded that a heart subjected to an increased pressure load is less able to respond to a superimposed volume load by an increase in its capillary supply than is a normal heart.

Animals↗
PubMed1975

Caplan's syndrome - a clinical study of 13 cases.

Thirteen cases of Caplan's syndrome were investigated by chest X-ray, rheumatic and immunological tests, heart and lung physiology and pathological-anatomical specimens. No positive correlation was found between exposure time to silica, roentgenolgical findings, degree of rheumatoid factor or physiological findings. In nine of the cases a rapid roentgenological progress took place. Although the combination of lung infiltrations and rheumatic disorders makes an immunological reaction probable, no correlation was found between the degree of rheumatic disorder and roentgenological progress. The hypothesis that silica acts as an adjuvant, which may strengthen an antigen-antibody reaction, was not reflected in rheumatic parameters. The roentgenological examination appeared to be the most sensitive method for following the disease.

Adult↗