Search PubMed⌕ Search

Biomedical subjects

G Tye

Publications and source records attributed to G Tye.

4 recordsLinked to original sources

Halting the illegal sale of prescription medications in Los Angeles County.

The illegal sale of prescription medications by unlicensed vendors is a widespread practice in Los Angeles County. Many members of ethnic and particularly Latino communities turn to unlicensed vendors because of financial and cultural reasons and/or a lack of access to the U.S. health care system. In response, Los Angeles County Department of Health Services developed a two-part effort to curb the illegal sale of pharmaceuticals. Dramatically increased law enforcement resulted in 280 investigations, 121 arrests, and the confiscation of $4-$4.5 million worth of illegal pharmaceuticals during the first 20 months. The department also has begun outreach efforts to educate those communities most affected by these practices.

Crime↗

Caffeine exposure in utero increases the incidence of apnea in adult rats.

Caffeine abuse during pregnancy may be a factor in the development of long-term breathing abnormalities. Therefore, the objective of the present study was to monitor adult breathing patterns after in utero exposure to caffeine. This was done by isolating episodes of apnea of more than 6-s duration from the breathing data as obtained by the Cotwatch breathing monitors adapted for rat use. The breathing record obtained over 6 consecutive days was expressed as daily weighted apnea-hypopnea density (WAHD) values. It was shown that administration of caffeine in moderate (30 mg/kg daily) or high (60 mg/kg daily) doses throughout gestation resulted in a significant dose-dependent increase in the WAHD value. The experimental offspring were significantly growth retarded in utero and their subsequent growth rates were also affected. The caffeine-exposed pups grew more slowly with growth plateauing at the same age, resulting in smaller adults. A link was suggested between infants with apnea of prematurity, when occurring after the first week, and an increased risk for later apnea and sudden infant death syndrome.

Animals↗