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Biomedical subjects

G Tu

Publications and source records attributed to G Tu.

40 records · Page 3Linked to original sources

[Primary malignant tumours in submandibular region].

From 1959 and 1989, 65 patients with primary malignant tumour of submandibular region, including 18 cases of adenoid cystic carcinoma, 16 cases of malignant mixed tumour, 14 cases of adenoid carcinoma, 10 cases of undiferentiated carcinoma and 7 cases of squamous cell carcinoma, were treated at this hospital by surgery or combined therapy. The 3- and 5-year survivals were 60% and 42.9%, respectively. Those of malignant mixed tumours were somewhat better, being 75% and 61.5%. Submandibular gland excision or regional/elective dissection was used if the tumours were local and no capsule invasion. Particular attention was given to the identification of perineural invasion, softtisure extension, bone invasion and lymph node metastasis. Wide excision and neck dissection were necessary for above mentioned pathological changes. Combined therapy was important for those patients with positive margin, recurrence, low- or un-differentiation and advanced stage. The main factors affecting survival were local-regional failure.

Adult↗

[Near-total laryngectomy in the treatment of advanced laryngeal and hypopharyngeal carcinoma].

Near-total laryngectomy was first introduced by RB Pearson in 1980. In this report, 14 cases (T3, T4 laryngeal cancer 10 cases, pyriform fossa 3, cervical esophagus 1) treated with near-total laryngectomy. The speech function was obtained in 12/14 (85.7%) within 2 to 5 weeks, all cases had good swallowing. 2-year survival rate is 78.6%. The authors believed that such surgical technic is most indicated in the cases when regular partial laryngectomy can not be performed and in elderly cases who would have the risk with partial laryngectomy.

Aged↗

The superiority of combined therapy (surgery and postoperative irradiation) in parotid cancer.

A retrospective evaluation was done on 120 patients treated for parotid cancer. The aim of the study was to establish the role of postoperative radiation therapy. Fifty-nine patients were treated by surgery plus postoperative radiation therapy. Two patients were treated by preoperative irradiation. The overall 5-, 10-, and 15-year survival rates were 81%, 62%, and 65%, respectively. Postoperative radiation therapy proved to increase local control over surgery alone whenever (1) there was locally advanced disease, (2) the tumor belonged to a so-called poorly differentiated variety, (3) the treatment was given for a recurrent lesion, and/or (4) there was tumor involvement of the facial nerve. It did not appear that postoperative radiation therapy increased the survival for patients with low-grade malignant tumors. Radiation therapy should be given as early as possible after surgery and the optimum dose ranges from 3,000 to 5,000 rad given in three to five weeks, respectively.

Facial Nerve↗