Search PubMed⌕ Search

Biomedical subjects

G Trovato

Publications and source records attributed to G Trovato.

At least 19 recordsLinked to original sources
PubMed2006

Abdominal aortic aneurysm associated with abdominal visceral diseases.

Abdominal aortic aneurysm (AAA) occurs in advanced age. As such, its frequency has increased with the general ageing of the population as has the possibility of finding AAA associated with abdominal visceral disease, especially neoplasms. A malignant mass is present in 4% of patients who undergo aortic reconstruction for AAA. Since surgical treatment for both is often potentially life-threatening, the surgeon is faced with a series of treatment decisions concerning foremost timing of the operation. The main worry is that simultaneous treatment carries a potential risk of infection of the vascular graft. On the other hand, a 2-phase procedure is also burdened by risks linked to a second anaesthesia and a second surgical operation carried out on scar or contaminated tissue and the worsening of one of the 2 potentially life-threatening illnesses. In this situation endovascular treatment of an AAA may represent an advantageous alternative therapeutic strategy.

Aortic Aneurysm, Abdominal↗
PubMed1997

[Urticarial vasculitis syndrome. A case report and review of the literature].

Urticarial vasculitis (UV) is a primary syndrome or a cutaneous vasculitic lesion occurring in the course of a collagen disease, as the systemic lupus erythematosus (LE). UV is a recently recognized disorder which affects most exclusively the female sex and may be differentiated from common (nonvasculitic) urticaria because it is characterized by inflammation and necrosis of blood vessels (vasculitis). UV and common urticaria may be induced by a variety of factors and pathogenetic mechanisms. It seems that a continuum exists, ranging from benign cutaneous lesions of urticaria to vasculitis with strong immunological involvement. On the basis of the clinical evaluation, two major groups of UV have been classified, the normocomplementemic, with a less severe clinical course, and the hypocomplementemic UV, a rare immune complex-mediated disorder related to LE as for as the similar pathogenesis and systemic involvement are concerned. A case of a young female patient with a unique syndrome characterized by crises of urticarial recurrent painful lesions of unknown origin, associated with angioedema of the tongue and soft palate, severe malaise, arthralgias and abdominal pain is reported. Dyspnea and cough were sometimes present, but fever was absent. Symptoms were caused by physical stress, heat or pressure and were little responsive to corticosteroids. Although skin biopsy did not prove with certainty the occurrence of vasculitis, clinical data and laboratory findings (normal levels of complement fractions, raised erythrocyte sedimentation rate, presence of cryoglobulins and ASMA, nDNA and AMA autoantibodies and absence of ANA autoantibodies and LE cells) suggest a normocomplementemic UV, excluding a classic LE. The family doctors and the internist must become familiar with the "lupus-like" syndromes, which include UV. In fact, a correct diagnosis of this syndrome is important because, although prognosis of UV may not be severe, the possibility exists of a systemic involvement (mainly renal) with progression to LE.

Adult↗
PubMed1993

[The relation of moderate alcohol drinking and congestive heart insufficiency].

116 patients (53 women and 63 men) with congestive heart failure, secondary to chronic ischemic heart disease and/or hypertensive heart disease, were studied with the aim of assessing effects of moderate alcohol use on the clinical features of the disease. Two subgroups were considered: a) 57 moderate drinkers (11 women and 46 men); b) 59 non-drinkers or ex-drinkers (42 women, 17 men). Left ventricular mass/m2 (LVM/m2) is higher among moderate drinkers in comparison with non-drinkers (p < 0.001); this difference is present both in men (p < 0.05) and in women (p < 0.001). These results suggest that higher LVM/m2 of drinkers does not depend on sex and cigarette smoking; i.e., in males, a subgroup with the same prevalence of cigarette smokers among drinkers and non drinkers, congestive heart failure of drinkers is associated with a greater left ventricular enlargement. Our results suggest that moderate alcohol use can represent an additional pathogenetic factor for more severe clinical and laboratory features of congestive heart failure.

Aged↗
PubMed1991

[Further data on the spread to Genoa of Aedes albopictus].

Further data are presented on the presence of Aedes albopictus in the town of Genoa (Italy) where this oriental mosquito was first reported in September 1990. Scattered foci of Ae albopictus were documented during the 1991 summer months in spite of a rather long and rigid '90-'91 winter season with temperatures frequently below 0 degree C. The newly imported mosquito shows the capacity to become a permanent pest in Italy where it could also increase the probability of transmission of pathogens such as arboviruses and filariae.

Aedes↗
PubMed1990

[Aedes albopictus in Italy and possible diffusion of the species into the Mediterranean area].

Aedes albopictus (Skuse), the important Asian vector mosquito recently introduced in United States and Brazil, is reported from Genoa, North Italy. The infestation was discovered in a kindergarten pre-school center in September 1990 just after the summer holidays. Many discarded tires, well known to provide excellent breeding places for Ae albopictus, had been left in the school playground to be used as toys by the children. After sampling a few biting mosquito specimens for identification, the local health service carried out on September 18 an extensive indoor/outdoor treatment with pyrethroid insecticide. The extent of the infestation in the city of Genoa and in other areas of the Ligurian region has not been evaluated since the identification of the species was available in October, at the end of Ae albopictus reproductive period. A general survey in various Italian regions is being planned for the 1991 spring-summer period. The present record, together with the previous report of Ae albopictus in Albania, clearly supports the hypothesis of a spreading of the species in the Mediterranean area.

Aedes↗
PubMed1982

Effects of cyclic somatostatin on insulin, C-peptide and immunoreactive glucagon response to oral glucose loading in obese patients.

The effects of somatostatin (SRIF) infusion on blood sugar, immunoreactive insulin (IRI), immunoreactive glucagon (IRG) and C-peptide after administration of oral glucose load (100 g) to 23 obese subjects were examined. The latter were divided in two groups according to oral glucose tolerance (OGTT): (1) normal OGT; (2) impaired OGT. During SRIF infusion IRI and C-peptide response to oral glucose was significantly reduced in both groups as compared with the response under saline infusion. Blood sugar values fell markedly in the second group. After SRIF infusion ended a marked increase in C-peptide, IRG and blood sugar was observed. The results suggest that SRIF infusion is only able to inhibit the release of IRI and IRG temporarily. They do not demonstrate if the behaviour of blood sugar is influenced by variations of these hormones or by the direct effect of SRIF infusion on absorption of the glucose load.

Adult↗
PubMed1978

Serum total lipids, lipoproteins cholesterol, apoproteins A and B in cardiovascular disease.

Serum total lipids and lipoproteins cholesterol were determined in 33 survivors of myocardial infarction (MI) and in 75 subjects with peripheral vascular disease (PVD). Measurements were also made by a quantitative immunological assay of Apoprotein A (Apo A) and B (Apo B). Apo A levels were significantly lower in cases than in controls. In those cases with low levels of Apo A, high density lipoprotein has a higher cholesterol content as compared with controls. A negative correlation between high density lipoprotein cholesterol and low density lipoprotein cholesterol was found in controls and PVD subjects. The findings suggest that Apo A is associated to MI and PVD and its quantitative determination is predictive of cardiovascular disease.

Adult↗
PubMed1978

[Behavior of total lipids, cholesterol, lipoproteins and apolipoprotein A in the blood of subjects with acute hepatitis and chronic hepatopathy].

Serum total lipids, lipoprotein cholesterol, apolipoprotein A (Apo A) and liver function parameters have been investigated in patients with acute viral hepatitis and chronic liver disease. Hypertriglyceridaemia, absence of alpha and pre beta bands on the lipoprotein electrophoresis pattern, low level of Apo A, presence of abnormal lipoproteins (beta-VLDL and beta2-LP) were observed in the early phase of acute hepatitis. A positive correlation was found between Apo A and triglyceride bile acids, log total bilirubin, log SGPT. Lipoprotein abnormalities are probably due to low lecitin-cholesterol aciltransferasi activity. The reappearance of alpha lipoprotein and the increase of Apo A are sensitive indices of improvement of liver function. In chronic liver disease the levels of cholesterol and Apo A correlate with changes in the hepatocellular function.

Acute Disease↗
PubMed1978

Serum total lipids, lipoprotein cholesterol, and apolipoprotein A in acute viral hepatitis and chronic liver disease.

Serum total lipids, lipoprotein cholesterol, apolipoprotein A (Apo A), and liver function tests have been investigated in patients with acute viral hepatitis and chronic liver disease. Hypertriglyceridaemia, absence of alpha and pre beta bands on the lipoprotein electrophoresis pattern, low level of Apo A, and presence of abnormal lipoproteins (beta-VLDL and beta2-LP) were observed in the early phase of acute hepatitis. A positive correlation was found between Apo A and high-density lipoprotein cholesterol, and a negative one between Apo A and triglyceride, bile acids, total bilirubin, and serum alanine aminotransferase. Lipoprotein abnormalities found in the early phase of acute hepatitis are probably due to low lecithin-cholesterol acyltransferase activity. The reappearance of alpha lipoprotein and the increase of Apo A are sensitive indices of improvement of liver function. In chronic liver disease low levels of cholesterol and Apo A indicate the severity of liver cell injury.

Apolipoproteins↗
PubMed1977

[Prognostic and therapeutic considerations on intraventricular block during a course of acute myocardial infarct].

Intraventricular block was observed in 10% of a series of 250 cases of acute myocardial infarct observed at the Medical Division, S. Angelo Hospital, Messina. Mortality was not strictly related to the presence of block, though this was a negative factor in prognosis, but essentially to the degree of myocardial efficiency. It is felt that temporary pacemakers should only be fitted where myocardial insufficiency is slight, though this step can also be taken in more serious cases until further clinical evidence finally establishes the question of treatment.

Acute Disease↗