Three strains of Neisseria meningitidis were isolated from young patients during an outbreak of cerebrospinal fever in Palermo, fourteen from their family contacts. All strains from patients and ten of the strains from contacts fell into group C, two of the others into group B; two were untypable strains. All the strains belonging to group C exhibited sensitivity to sulphonamides and to other antibiotics tested. Strains of group B appeared resistant to sulphonamides and to combined trimethoprim-sulphamethoxazole; they were also slightly resistant to streptomycin and tetracyclines.

Disease Outbreaks↗

PubMedDate not supplied

[Antibody response in subjects with meningococal disease and in healthy carriers of Neisseria meningitidis].

Antibodies against Neisseria meningitidis in sera of childrens suffering from cerebrospinal fever and in sera of their family contacts were assayed by serum bactericidal test, indirect immunofluorescence and passive hemagglutination. Changes in antibody titers were showed in the course of the observations in many patients but only in few contacts. The immune response during meningococcal disease and the sensitivity of different serological methods were discussed.

Antibodies, Bacterial↗