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Biomedical subjects

G Tramontano

Publications and source records attributed to G Tramontano.

7 recordsLinked to original sources

Single-step treatment of gallbladder and bile duct stones: a combined endoscopic-laparoscopic technique.

BACKGROUND: The introduction of laparoscopic cholecystectomy has given rise to a debate as to whether endoscopic retrograde cholangiopancreatography (ERCP) should be performed before or after cholecystectomy in patients with bile duct stones. METHODS: This study evaluated the efficacy of treatment of cholecystocholedocholithiasis in a single step by performing ERCP during surgery in 52 patients (35 women, 17 men; mean age 57.0 years; age range 20 to 89 years). Laparoscopic intraoperative cholangiography via the cystic duct was carried out to confirm the presence of duct stones. A soft-tipped guidewire was passed through the cystic duct and papilla into the duodenum. A papillotome was inserted endoscopically over the guidewire. Endoscopic sphincterectomy was performed and the stones removed with balloon and basket catheters. RESULTS: Endoscopic stone removal was successful in 94% of cases without complications related to ERCP or surgery. Although operative time was lengthened by about 20 minutes, the hospital stay was as short and equal to that for simple laparoscopic cholecystectomy (3 days on average). CONCLUSIONS: The single-step combined endoscopic-laparoscopic technique is safe and effective for treatment of patients with gallbladder and bile duct stones.

Adult↗

[Diagnosis, therapy, and follow up in synchronous colorectal cancer of the colon].

The authors report their experience with synchronous colorectal cancers (CRC). They underline the role of pre-operative diagnosis to improve surgical results and overall survival. The endoscopic surveillance allows the identification of neoplasms missed at previous examinations. In selected cases intraoperative colonoscopy may prove to be helpful.

Aged↗

Speed of information processing in traumatic brain injury: modality-specific factors.

OBJECTIVE: To assess speed of information processing by two serial addition tests (one visual, one auditory) in individuals with moderate-to-severe traumatic brain injuries (TBIs) and in a healthy, normal control group (NC). The tasks were designed to equate and control for accuracy of performance across the TBI and NC groups, thus allowing for quantification of information processing speed. DESIGN: Performance across groups and tasks were compared using 2 x 2 repeated measure analyses of variance (ANOVAs). In addition, each individual's processing speed was used to adjust rate of stimulus presentation on a subsequent "rehabilitation" trial to determine further whether this adjustment equated accuracy of performance. SETTING: Rehabilitation hospital. PATIENTS: 22 outpatients with moderate-to-severe TBI (6 women, 16 men; mean age = 34.6 years; duration of loss of consciousness = 22.6 days) and 20 age- and education-matched healthy controls. RESULTS: Processing speed was slower in TBI subjects, relative to controls and was significantly related to measures of executive functioning for those with TBI. Relative to controls, speed of processing in the TBI group was disproportionately slower when information was presented in the auditory, relative to the visual, modality. CONCLUSIONS: Speed of information processing is a major impairment in those with TBI when unconfounded by performance accuracy. The modality-specific impairment observed in the TBI group may, in part, be due to a greater within-modality interference effect created by the auditory version of the task. By manipulating information at a pace customized for an individual through compensatory strategies and environmental modifications, information-processing performance of TBI participants can be enhanced significantly.

Adult↗

Seasonal dependence of cadmium accumulation and Cd-binding proteins in Mytilus galloprovincialis exposed to cadmium.

At different periods of the year specimens of Mytilus galloprovincialis were exposed to 0.5 microg Cd/ml seawater for 7 days. Concentrations of trace elements (Cd, Zn, Cu and Fe) and Cd-binding proteins in gills, viscera, muscle and mantle were determined after 1 weeks exposure. Cadmium accumulation was higher in May and June and was tissue dependent; it was highest in the gills and decreased in the order: gills > viscera > mantle and adductor muscle. Significant seasonal variations of zinc, copper and iron, were also found, in both exposed and control molluscs. The percentage of Cd distribution between cytosol and pellet changed during the year; a clear shift from the particulate fractions to the cytosolic fractions was measured during May and June, especially in the gills. Metallothionein (MT) was the main ligand responsible for Cd accumulation, and this protein reached a maximum between May and June. Inclusion of mercaptoethanol during the purification procedure was found to improve MT isolation by gel chromatography. In the absence of mercaptoethanol, MT showed polymerization patterns which were season dependent and temperature independent, whereas its concentration was increased in mussels kept at higher temperature.

Animals↗

[Not Available].

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Dentistry↗

Primary carcinoma of the vagina. Case report.

An unusual case of Primary Carcinoma of the vagina was recently observed. The patient was treated surgically in 1981 for squamous cervical carcinoma in situ (CIN 3); eight years later the same patient was treated for squamous carcinoma of the vagina that involved the upper, median and lower tract. She was treated with radical colpectomy and VBP chemotherapy for three courses. The pathology, natural history and treatment are discussed.

Antineoplastic Combined Chemotherapy Protocols↗

[Schönlein-Henoch syndrome. Clinico-statistical analysis of 60 cases (1978-1984)].

Schonlein-Henoch purpura is a systemic, immunocomplex-mediated vasculitis which involves skin, joints, gastrointestinal and urinary system. This is a retrospective study on 60 S.H.S. admitted in our Division from 1978 to 1984. The most affected age range seems to be included between 2 and 7 years, with a maximum at 6. The Male/Female ratio is 35/25. Clinically we found skin (100%), joint (63%), abdominal (48%), and renal (25%) manifestations. Laboratory data are not characteristic: C3 and C4 are always in the normal range. 27% showed an elevation of IgA, 81% a rise of sedimentation rate and 45% a rise of Anti-O-Streptolysin Title. The main problem to face is prevention of glomerulonephritis. Salicylates, piridamol and cyproheptadine have been suggested to be effective. Prednisone is recommended in all cases with abdominal pain in order to prevent surgical complications. In our experience we could not demonstrate any difference between treated and not treated cases. It is important anyway to perform a correct follow-up of these children to early show a possible relapse or a renal complication.

Abdomen↗