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Biomedical subjects

G Tognoni

Publications and source records attributed to G Tognoni.

At least 325 records · Page 18Linked to original sources
PubMedDate not supplied

[P300 and Parkinson disease. The role of cognitive changes].

Cognitive disturbances are frequently encountered in advancing Parkinson's disease (PD). Typically there are visuo-spatial disorders, memory impairment and bradyphrenia, defined as 'subcortical dementia' to distinguish it from the dementia that occurs in Alzheimer's disease, where the most prominent dysfunctions are agnosia, apraxia and aphasia. An electrophysiological test to study cognitive processing is the P300 (or P3) of the Event Related Potentials; in particular the latency of the P3 seems to correlate with cognitive decline. Thirty patients affected with idiopathic PD were investigated using a classic auditory "oddball" paradigm (rare tone--"target"--3000 Hz, frequent tone--"non target"--1000 Hz; the patients were instructed to recognize and keep a mental count of the number of rare tones). Electrophysiological findings were compared with those obtained in twenty normal subjects, age and sex matched with the patient's group. The parameters of P300 were correlated with patient's age, duration of the disease, motor and cognitive impairment levels and L-Dopa therapy. The P300 was loss in 16.6% (5 p.) and delayed in 33.3% (10 p.). Significative correlations were found only with age and cognitive impairment scores, but not with other variables analyzed. These results suggest that P300 could be a useful test to identify demented patients among those with PD, despite different motor disabilities.

Aged↗
PubMedDate not supplied

[Circuses and clowns. Experimental contribution to nursing methodology].

The description of a very original experience of health education in a region of Amazonia, Brasil (based on the utilization of techniques of population theater) is the occasion for a reflection on the possibilities and on the opportunity of adopting also for the nursing practice of western countries methodologically innovative approaches, which could allow a caring attention oriented not only to the problem of assistance, but more basically to the cultural components of the needs and expectations of defined populations.

Brazil↗
PubMedDate not supplied

[Drugs and pregnancy].

The need for further information on drug utilization patterns during pregnancy in different countries was assessed by reviewing literature by hand and computer searches. The resulting profile, from 13 identified studies, was that pregnant women used an average of 4.7 drugs. The most commonly ingested medications were vitamins and iron preparations (almost all women), analgesics, antiemetics and antacids. However, important variables (such as date of surveillance; country; size of involved population; habits; physiopathological and demographic characteristics), differently taken into account in each selected study, made it impossible to construct a comprehensive, detailed, up-to-date picture about drug utilization during pregnancy. The evaluation confirmed the need for and value of systematic permanent surveillance of drug utilization in pregnancy, so as to avoid the use of data obtained in widely differing contexts, times, and methods, in a field where knowledge is often based on scanty information.

Abnormalities, Drug-Induced↗
PubMedDate not supplied

[Isolated systolic hypertension in the elderly].

Isolated systolic hypertension (ISH) is a very common condition in the elderly, even more than diastolic hypertension. Several studies indicate that ISH is a considerable cardiovascular risk factor in the elderly but the benefit of antihypertensive treatment has not been proved. Data in the literature on prevalence, pathophysiology, prognostic meaning and treatment of ISH are critically reviewed.

Aged↗
PubMedDate not supplied

[Lack of equality].

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Cause of Death↗
PubMedDate not supplied

[The ethics market].

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Bioethics↗
PubMedDate not supplied

[Evaluation of family satisfaction in pediatric oncology].

The satisfaction for the care receveid following the diagnosis of acute linfoblastic leukemia in the Pediatric Division of the San Gerardo Hospital of Monza was explored with a questionnaire to the families of patients diagnosed from January 1984. 217 questionnaires were returned (59.2%); 67% were completed by both parents. Parents expressed overall a very high satisfaction for several areas of care: 93.8% for the information about diagnosis; 83% approved the use of the word "leukemia". Judgements on technical competence and communication skills of the health care professionals were analyzed separately for hospitalized and day-hospital patients, and for survivors and dead: results were highly positive for both groups. The expected higher of missing data for the questions related to satisfaction for communication on relapses, highlights the difficulty and the emotional load of the question. Data were discussed by the health care team as well as parents in order to obtain a feedback and practical suggestions for further improvement of care.

Child↗
PubMedDate not supplied

[Experimenting curing-caring experimenting. Notes to prevent confusion].

Children, as well as adults, can be subjects of clinical trials. An overview of the history and development of clinical experimentation through the main scientific publications is briefly outlined. A chart of children rights is also presented and discussed. Children's rights range from the right of being included in clinical trials to the right of being participants in a research that complies, without being overwhelmed, with formal rules. The maximum respect for the child is assumed if innovative questions are asked and independence and autonomy of judgement of researches are observed.

Adult↗
PubMedDate not supplied

[Access to rehabilitation resources for an unselected hospital population of patients with acute seizures].

The study aimed at evaluating selection criteria and basic characteristics of acute stroke patients admitted to rehabilitation programs. From January 1993 to February 1994, 373 patients from 13 hospitals of the Lombardy region were admitted to the study. The 4 months telephone follow-up was performed by the AVO (Hospital Volunteers Association) volunteers. The 4 months fatality rate was 23%. The patients with a higher disability level were prescribed a rehabilitation program. Rehabilitation resources were not available for very severe or dependent patients being mostly the younger and partially dependent patients more often referred to the services. Only 50% of eligible patients received a rehabilitation intervention within 1 month from the index episode of stroke. The lack of caring resources and the long waiting times stress the need for a reorganization of the rehabilitation services. This study also shows that volunteers can play a role of stricter collaboration with doctors and are ready to collaborate in data collection. A larger and more detailed study is warranted in order to gain a better knowledge on the problem and on the clinical and social characteristics of the stroke victims.

Adolescent↗