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Biomedical subjects

G Tiberio

Publications and source records attributed to G Tiberio.

At least 91 records · Page 5Linked to original sources

Late modifications of residual parenchyma after splenic resections.

The increased experience in the field of splenic resections have brought up questions about the evolution of the residual parenchyma. Weight increase and the histologic structure of the splenic remnant were studied during a year following hemisplenectomy in rats. Histological studies show that the residual spleen presents a permanent compensatory hyperplasia rather than a true regeneration. This hyperplasia causes an increase in weight of the residual parenchyma which is moderate and only transitory. Indirect confirmation of findings obtained in rats comes from scintigraphic study of residual human splenic tissue after hemisplenectomy. The residual tissue keeps its original form without increase in volume, and the sectioned surface is always well identified one year after splenic resection.

Animals↗

Value of Doppler multi-level segmental pressure index in the diagnosis and hemodynamic characterization of totally occlusive aorto-iliac-femoro-popliteal lesions.

Four-level lower limb Doppler S.P.I. (upper thigh; above knee; below knee; above ankle) were evaluated in 275 limbs, 110 of which showed totally occlusive lesions at one or more levels of the aorto-iliac-femoro-popliteal axis on angiographic examination, 65 showed stenosis less than 50% (sclerotic controls) and 100 did not undergo arteriographic examination since they apparently had no lesions (healthy controls). Analysis of the results-carried out using the Student's t statistical method-showed a drop in the S.P.I. close to or over 0.30 between two adjacent levels and was indicative of the presence of an occlusion in the intermediate area. This method therefore allowed the presence and the position of an isolated lesion to be detected. In the case of multiple lesions in series, the proximal one is detected with certainty, whereas the more distal ones can be recognized but not their exact position and extension. Multiple lesions in series are more hemodynamically significant than isolated ones, and proximal lesions more than distal ones.

Aorta↗

Immunochemical and immunocytochemical study of S-100 protein in rat adipocytes.

S-100 is a protein originally believed to be unique to the nervous system. We report here on the presence of S-100 in rat adipocytes, using immunohistochemical and immunochemical methods. We demonstrate that the protein in adipose tissue is present at a concentration comparable to that measured in the nervous tissue and is immunologically identical to brain S-100, indicating that the protein can no longer be regarded as being specific to the nervous system.

Adipose Tissue↗

S-100 protein in "follicular dendritic" cells or rat lymphoid organs. An immunochemical and immunocytochemical study.

The presence as well as the cellular and subcellular distribution of S-100 protein were investigated in lymphoid organs of the adult rat by quantitative microcomplement fixation assay and by the immunocytochemical PAP method at the ultrastructural level. The protein appeared to be confined to the "follicular dendritic" cells both in the lymph node and the spleen, which are known to be exclusively associated with B lymphocytes in secondary follicles. The present data show an additional location for S-100 outside the nervous system. The protein may also be a useful tool to provide information on the origin and function of "follicular dendritic" cells, which are still poorly understood.

Animals↗