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Biomedical subjects

G Tibblin

Publications and source records attributed to G Tibblin.

At least 109 records · Page 6Linked to original sources
PubMed1985

Prospective study of social influences on mortality. The study of men born in 1913 and 1923.

In a study of 989 middle-aged men followed up for 9 years social influences, measured as persons per household unit, home activities, outside-home activities, and social activities at the baseline examination, were found to be significantly associated with mortality. The association between these variables (except for home activities) and mortality was significant even when age, risk factors for coronary heart disease, and health status measured at the baseline examination were taken into consideration. Social activities may have a modifying effect on life stresses and risk factors associated with mortality.

Activities of Daily Living↗
PubMed1985

Increasing mortality from coronary heart disease among males in Sweden.

In Sweden, coronary heart disease (CHD) mortality increased by 30% among 50- to 54-year-old men and by 20% among 55- to 59-year-old men between 1968 and 1980. Among women there was no change during the same time. Two cohorts of 50-year-old men living in Gothenburg, Sweden, were examined 10 years apart (1963-1973): Levels of the 3 major CHD risk factors, blood pressure, serum cholesterol and smoking habits, were similar in these two cohorts. Men in the latest examined cohort had almost doubled the 7-year incidence of fatal and non-fatal CHD compared to men in the first examined cohort. Obesity was more prevalent among men examined in 1973 and also a significant risk factor for CHD in that cohort. Increased obesity and very slightly increased serum cholesterol levels can, however, only explain part of the increased incidence of CHD. Hypertension is being more effectively treated, the prevalence of smokers has decreased, and treatment of symptomatic CHD is similarly active in Sweden as in many other countries. Thus, several changes largely parallel those taking place in countries with decreasing CHD mortality. In spite of this, CHD mortality is increasing among males in Sweden. Possible reasons for this are discussed.

Blood Pressure↗
PubMed1985

The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913.

In a prospective study of risk factors for ischemic heart disease, 792 54-yr-old men selected by year of birth (1913) and residence in Göteborg, Sweden, agreed to attend for questioning and a number of anthropometric and other measurements in 1967. Thirteen and one-half years later, these baseline findings were reviewed in relation to the number of men who had subsequently developed diabetes mellitus. This analysis focused on the importance of abdominal adipose tissue distribution, measured as the waist-to-hip circumference ratio, as a predictor for development of diabetes. Even when the confounding effect of body mass index, as a measure of the total body fat mass, was accounted for, the waist-to-hip ratio was positively and significantly associated with the risk for diabetes. These results from a prospective study strongly support previous cross-sectional findings indicating that not only the degree of obesity but also the localization of fat is a risk factor for diabetes.

Abdomen↗
PubMed1985

Introduction to the epidemiology of dyspepsia.

When discussing epidemiological data we must consider the tools of assessment and the selection of the target population. As a rule, well designed population studies give us an accurate but crude picture of what is going on. What we gain in details with a more elaborate method we often lose when we want to generalise. Population studies in Göteborg have shown that the prevalence of dyspepsia is the same among men and women in the age groups between 30-70 years. After the age of 50 dyspepsia is less common. With the methods described, it was not possible to make a clear distinction between the ulcer dyspepsia group and the non-ulcer dyspepsia group except for smoking (which was more common in the ulcer dyspepsia group).

Adult↗
PubMed1984

Fibrinogen as a risk factor for stroke and myocardial infarction.

To study the possible risk factors for cardiovascular disease, we collected data on plasma levels of coagulation factors, blood pressure, serum cholesterol, and smoking in a random sample of 792 men 54 years of age. During 13.5 years of follow-up, myocardial infarction occurred in 92 men, stroke in 37, and death from causes other than myocardial infarction or stroke in 60. The blood pressure, degree of smoking, serum cholesterol, and fibrinogen level measured at the base-line examination proved to be significant risk factors for infarction by univariate analyses during follow-up, and blood pressure and fibrinogen were risk factors for stroke. Fibrinogen and smoking were strongly related to each other. The relation between fibrinogen and infarction, and between fibrinogen and stroke, became weaker when blood pressure, serum cholesterol, and smoking habits were taken into account, but was still significant for stroke. Although causality cannot be inferred from these data, it is possible that the fibrinogen level plays an important part in the development of stroke and myocardial infarction.

Blood Coagulation Factors↗
PubMed1984

Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913.

In a prospective study of risk factors for ischaemic heart disease 792 54 year old men selected by year of birth (1913) and residence in Gothenburg agreed to attend for questioning and a battery of anthropometric and other measurements in 1967. Thirteen years later these baseline findings were reviewed in relation to the numbers of men who had subsequently suffered a stroke, ischaemic heart disease, or death from all causes. Neither quintiles nor deciles of initial indices of obesity (body mass index, sum of three skinfold thickness measurements, waist or hip circumference) showed a significant correlation with any of the three end points studied. Statistically significant associations were, however, found between the waist to hip circumference ratio and the occurrence of stroke (p = 0.002) and ischaemic heart disease (p = 0.04). When the confounding effect of body mass index or the sum of three skinfold thicknesses was accounted for the waist to hip circumference ratio was significantly associated with all three end points. This ratio, however, was not an independent long term predictor of these end points when smoking, systolic blood pressure, and serum cholesterol concentration were taken into account. These results indicate that in middle aged men the distribution of fat deposits may be a better predictor of cardiovascular disease and death than the degree of adiposity.

Abdomen↗
PubMed1983

Why is the incidence of ischaemic heart disease in Sweden increasing?: study of men born in 1913 and 1923.

The mortality from ischaemic heart disease (IHD) in the USA is falling, and this has been attributed to a changing life-style, with less smoking, more jogging, and less fat consumption, and to improved medical care. Similar changes in life-style are taking place in Sweden, but IHD mortality there is increasing. The rising incidence of IHD was also evident in two cohorts of 50-year-old Swedish men examined 10 years apart. Despite similar levels of traditional IHD risk factors, the incidence of IHD in the second cohort was almost double that in the first. Possible explanations for the increasing IHD mortality are an increasing prevalence of obesity in Swedish men, a longer "incubation" time during which the traditional risk factors have acted in the second cohort, or the appearance of unknown risk factors.

Aged↗
PubMed1982

Home blood pressure measurements--feasibility and results compared to office measurements. The study of men born in 1913.

Blood pressure (BP) readings in a physician's office have been reported to be higher than patient-determined readings at home. This conclusion is based on measurements in various selected groups of patients. In this study, the results of office and home BP readings were compared in three groups of men with high BP sampled from the general population. More than 90% of the men were able to perform the measurements. Among men well accustomed to the office environment, the differences between office and home readings were small and without any clinical importance. Among men less well accustomed to the office atmosphere, the office readings exceeded almost invariably the home BP.

Ambulatory Care↗
PubMed1982

The influence of repeated health examinations on mortality in a prospective cohort study, with a comment on the autopsy frequency. The study of men born in 1913.

In the Study of Men Born in 1913 it was possible to investigate the influence of repeated health examinations on mortality in a prospective cohort study. On January 1, 1963, 1010 men in the experimental group and 1956 in the control group were alive. The experimental group took part in repeated examinations in 1963, 1967, 1973 and 1980. Overt diseases were treated accordingly. Newly detected hypertension was also treated. By the end of a 15-year-long observation period, the cumulative mortality in the experimental group (14.5%) was not significantly lower than that in the control group (15.7%). In the experimental group, 855 took part. The mortality was significantly higher in the non-participating group. The autopsy frequency decreased for in-hospital deaths but increased for deaths outside hospital during the study period.

Autopsy↗
PubMed1981

Nine years' follow-up of a maximal exercise test in a random population sample of middle-aged men.

A stepwise bicycle exercise test up to maximum was performed in a random population sample of 793 Swedish men, all aged 54 years. High respiratory rate during exercise characterized those who later suffered myocardial infarction (MI) or sudden coronary death (SD). In addition to high cholesterol, high blood pressure (BP), and smoking, low maximal performance, but not ST changes during exercise, increased the risk of MI + SD also in multivariate analysis. Pulse rate, systolic BP at both submaximal and maximal work load were positively correlated with the initial blood pressure level. BP at these work loads was also positively correlated with subsequent BP increase.

Blood Pressure↗
PubMed1979

Mortality and morbidity during 13.5 years' follow-up in relation to blood pressure. The study of men born in 1913.

A total of 973 50-year-old men, randomly selected from the general population in Göteborg, Sweden, were invited to a survey in 1963. Altogether 855 men (88%) participated. They have been followed up for 13.5 years, and this report presents mortality and morbidity during this time in relation to BP at the time of the initial examination. BP was strongly associated with mortality regardless of its cause. This was due to a close relation of BP to mortality from ischaemic heart disease and a weak but significant relation to mortality from cancer. BP was also strongly related to morbidity from myocardial infarction, stroke and angina pectoris, showed a tendency towards relation to morbidity from intermittent claudication and kidney stone, and was negatively related to morbidity from neoplasm for survivors. BP was also related to pension but not to sick leave. There is no indication of a decreasing importance of BP as a risk factor in this age period.

Aged↗