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G Stucki

Publications and source records attributed to G Stucki.

130 records · Page 8Linked to original sources
PubMedDate not supplied

[Critical evaluation of economic analysis exemplified by preventive misoprostol administration in antirheumatic drug-induced gastropathy].

Public and professional concern about the limited resources and increasing costs of medical care in absolute and relative terms have stimulated research on the costs and benefits of health care programs and interventions. The identification of cost-effective alternatives requires the choice of the type of analysis, definition of the perspective, comprehensive assessment of the costs as well as the effects and the critical interpretation of the results. These aspects are illustrated with the example of misoprostol-prophylaxis for NSAID-induced gastropathy. A summary of relevant criteria for an economic analysis in clinical practice is provided.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMedDate not supplied

[Evaluation of a German version of WOMAC (Western Ontario and McMaster Universities) Arthrosis Index].

The WOMAC (Western Ontario and McMaster Universities) Osteoarthritis Index is a tested questionnaire to assess symptoms and physical functional disability. We adapted the WOMAC for the German language and tested its metric properties, test-retest reliability and validity in 51 patients with knee and hip OA. All WOMAC scales (pain, stiffness, function) were internally consistent with Cronbach's coefficient alpha ranging from 0.80 to 0.96. Test-retest reliability was satisfactory with intraclass correlation coefficients ranging from 0.55 to 0.74. All scales and the global index calculated as the mean of scale scores had a bimodal distribution and a slight ceiling effect. As hypothesized the WOMAC scales were associated with radiological OA-severity and limitations of range-of-motion. Patients with more severe symptoms and functional disability perceived more limitations in their roles at home and at work. The presented German version of the WOMAC is a reliable and valid instrument for the assessment of symptoms and physical functional disability in patients with knee and hip OA.

Activities of Daily Living↗
PubMedDate not supplied

[Evaluation of a German questionnaire version of the Lequesne cox- and gonarthrosis indices].

The Lequesne algofunctional indices for the knee and the hip require a physician interview. We adapted the Lequesne indices for the German language and tested the metric properties, test-retest reliability and validity of a self-report questionnaire-format in 51 patients with hip or knee OA. The symptom and function components as well as the global indices had a high test-retest reliability (intraclass correlation coefficient knee: 0.87/0.92 and 0.86, hip: 0.96/0.85 and 0.94). The symptom component showed an insufficient internal consistency (Cronbach's coefficient alpha knee: 0.55; hip: 0.63). Also, the symptom component was not or only weakly associated with radiological OA-severity and the limitations of range-of-motion. The most likely explanation is the grading of the Lequesne symptom questions which addresses such different concepts as pain presence, pain on movement, duration of pain and appearance of pain after a certain period of time. Because of the insufficient internal consistency and questionable validity the tested self-report German-version of the Lequesne algofunctional indices may not be recommended for use in clinical research and practice.

Activities of Daily Living↗