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Biomedical subjects

G Strasser

Publications and source records attributed to G Strasser.

At least 37 records · Page 2Linked to original sources
PubMed1998

[The quality offensive in radiology].

The Institute of Diagnostic Radiology at the Heinrich-Heine-University Duesseldorf has recently defined and implemented more than thirty organizational changes as a result of a quality control project. The aim was to improve quality and efficiency of the Radiology service. The project was carried out in cooperation with an external consulting firm. To date the positive impact of this project on our work has been so profound that we would like to communicate some of the results in form of this report. During the first phase of the project quality circles were formed to define the various quality criteria and aims of a good service. Today these represent the core of a new quality policy for the Institute. In a second phase all members of staff cooperatively developed precise plans of action for implementation of the necessary changes. Main achievements are the reduction of organizational and communicational deficits obstructing the work process, enhancement of interaction between junior and senior medical staff, upgrading of the role and field of action of the radiography staff and last but not least improvements of cooperation between secretarial and medical staff.

Forecasting↗
PubMed1998

Radiographic findings in patients with acquired immunodeficiency syndrome, pulmonary infection, and microbiologic evidence of Mycobacterium xenopi.

The authors studied radiographs and clinical histories of 29 patients with acquired immunodeficiency syndrome, symptoms of pulmonary infection, and simultaneous microbiologic evidence of Mycobacterium xenopi in the respiratory tract. The presence, nature, and distribution of radiographic abnormalities were determined and analyzed in accord with clinical information. In 26 (90%) patients, M. xenopi was the only microorganism that could be isolated. Chest radiographs were normal in 13 patients (45%) and abnormal in 16 patients (55%). Radiographic abnormalities were bilateral in 94% of cases and predominantly involved the lower lobes. Patchy peribronchial opacities (44%) and miliary nodules (24%) were the most common abnormalities. Reticular opacities and parenchymal consolidation were seen in 12% of patients. Pleural effusion was seen in 18% of patients. No patients had cavitations or adenopathy. There was no statistically significant difference regarding the mean age (38.7+/-7.3 years vs. 40.2+/-11.0 years), the duration of clinically evident human immunodeficiency virus infection (2.7+/-1.2 years vs. 2.8+/-1.4 years), and the mean of CD4 cell counts (50.6+/-15.3 cells/ml vs. 47.4+/-15.9 cells/ml) between the patients with and without abnormalities on chest radiographs. In patients with acquired immunodeficiency syndrome, pulmonary infection, and simultaneous microbiologic evidence of M. xenopi, chest radiographs can be normal in a substantial number of cases. When radiographic abnormalities are present, they differ from those seen in patient not infected with the human immunodeficiency virus who had pulmonary infection caused by M. xenopi and from patients with acquired immunodeficiency syndrome and pulmonary infection with nontuberculous mycobacteria other than M. xenopi. Although these findings are not specific, they may be of importance in the imaging of patients with acquired immunodeficiency syndrome, notably in areas where M. xenopi is endemic.

AIDS-Related Opportunistic Infections↗
PubMed1997

Purification and characterization of a homodimeric catalase-peroxidase from the cyanobacterium Anacystis nidulans.

Cytosolic extracts of the cyanobacterium Anacystis nidulans exhibit both catalase and o-dianisidine peroxidase activity. Native polyacrylamide gel electrophoresis demonstrates one distinct enzyme, which has been purified to essential homogeneity and found to be composed of two identical subunits of equal size (80.5 kDa). The isoelectric point is at pH 4.7. It is a very efficient catalase with a broad pH optimum between 6.5 and 7.5 and a Km for H2O2 of 4.3 mM, a calculated turnover number of 7200 s(-1), and an overall-rate constant of 3.5 x 10(6) M(-1) s(-1). The behaviour of this protoheme-enzyme is typical of the class of prokaryotic catalase-peroxidases, which is sensitive to cyanide (Ki = 27.2 microM) and insensitive to the eukaryotic catalase inhibitor 3-amino-1,2,4-triazole. The enzyme accepts electrons from o-dianisidine, but not from ascorbate, glutathione, and NADH. With hydrogen peroxide in steady-state conditions the enzyme is mainly in the ferric state indicating that Compound I is much faster reduced by H2O2 than it is formed. The native enzyme is in the high-spin state, which is transformed to low-spin upon addition of cyanide. With peroxoacetic acid Compound I is formed at a rate of 5.9 x 10(4) M(-1) s(-1) at pH 7.0 and 25 degrees C with about 50% hypochromicity, a Soret-maximum at 405 nm and isosbestic points at 354 and 427 nm.

Amitrole↗
PubMed1997

[Video stereophotography of the optic papilla. A practice-oriented documentation].

Video documentation of the posterior pole using a camera installed in the ocular part of a slitlamp provides visualization of the optic disc from two different angles by changing the ocular part with the camera from the right to the left. Using the appropriate video printer program (split 4) two pictures of the right optic disc are stored on the upper half, one shooting from the right the other from the left. The lower half of the print is reserved for the left optic disc. Thus stereoscopic perception of the optic discs can be achieved. By this means a simple procedure has been provided for improved follow up of glaucoma patients.

Documentation↗
PubMed1987

[Condition and satisfaction of patients after gynecologic surgery].

The effects of gynaecological operations on the well-being and satisfaction of patients can be viewed as important supplements to quality assurance which is mainly based on clinical parameters and medical ratings. In the present study 215 patients undergoing gynaecological operations assessed different components of their subjective health status at times of admission to the hospital, at discharge and six weeks after discharge. Additionally, the patients gave satisfaction ratings at discharge. The study resulted in demonstrating considerable improvements of complaints and well-being that continued into the postdischarge period. The improvements were most pronounced in the cases of patients with vaginal hysterectomy. Satisfaction with the hospital department was high, especially with regard to the care given by the physicians and the nurses. After mastectomy, women expressed problems with their self-image and with their partners. Considerations to take the results of the study into account for quality assurance are discussed.

Adult↗
PubMed1987

[Primary therapy of acute angle-block glaucoma].

Primary therapeutic measures in 94 eyes suffering from acute angle-closure glaucoma were assessed in a retrospective study. Sixty-eight eyes were treated with acetazolamide, timolol, and pilocarpine. The remaining 26 eyes were treated with acetazolamide and timolol only. The therapy without pilocarpine proved to be significantly more effective.

Acetazolamide↗
PubMed1987

[Cryocoagulation of a prolapsed iris in hypertensive uveitis].

An ICCE was complicated by iris prolapse. Three years later the eye appeared quiet and intraocular pressure was normal when the patient was admitted for secondary implantation. An uneventful IOL implantation (CILCO MT 4U) was followed by hypertensive uveitis. Local and systemic corticosteroids and antihypertensive treatment were insufficient. Cryocoagulation of the bleb was performed. The inflammation rapidly subsided and intraocular pressure normalized without further therapy.

Aged↗
PubMed1987

[A new iridocorneal endothelial syndrome].

Three iridocorneal endothelial syndromes are distinguished: essential progressive iris atrophy, iris nevus (Cogan-Reese) syndrome, and Chandler's syndrome. Obviously, there are patients in whom findings do not correspond fully to any one of the three syndromes; signs and symptoms which justify being considered as a new iridocorneal endothelial syndrome are described.

Atrophy↗
PubMed1986

[An unusual cause of amblyopia ex anisometropia].

The case history is reported of an infant with a capillary haemangioma in the superior temporal quadrant of the anterior right orbit. Radiotherapy was not performed in view of the well-known tendency of these tumours to involute. Constant pressure on the globe led to marked oblique astigmatism of the eye with consequent amblyopia, in spite of complete regression of the lesion. The tendency of such tumours to regress must be weighed against possible irreversible functional impairment when a decision is made as regards treatment of neonatal haemangiomas in the region of the orbit.

Amblyopia↗
PubMed1986

Autologous hair implantation for drainage in rabbit eyes.

Autologous hair material was used as a wick for drainage from the anterior chamber into the subconjunctival space in 8 rabbits. Though pressure reduction and methylene blue leakage was evident in the operated eyes, the histological observations seemed rather discouraging.

Animals↗
PubMed1986

[Argon laser trabeculoplasty in glaucoma with a narrow chamber angle].

In 49 eyes (33 patients) with open-angle glaucoma and narrow angle, which did not respond to conservative therapy, argon laser trabeculoplasty (ALT) was performed after preparative gonioplasty. The success rate was 65.3%. A postoperative rise in IOP was observed in 44.3%, and aqueous humor flare in 63.3%. Goniodysgenesis proved to be prognostically unfavorable for ALT.

Follow-Up Studies↗