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Biomedical subjects

G Stores

Publications and source records attributed to G Stores.

66 records · Page 4Linked to original sources
PubMed1975

Behavioural effects of anti-epileptic drugs.

There is increasing evidence that various types of behavioural disturbance, other than those described for phenytoin, for example, may occur from the use of anti-epileptic medication, and it has been suggested that these disturbances may not always be reversible. There are suspicions also that certain groups of patients--especially those with structural brain damage--are particularly susceptible. These and other factors relevant to the study of the effects of anti-epileptic drugs on behaviour are comprehensively reviewed. It is concluded that the psycho-pharmacology of anti-epileptic drugs is unsatisfactory at present because of inadequate and unsophisticated reporting of behavioural change and because of the common problem of polypharmacy, and that more accurate observations are needed on less heterogeneous groups of patients that have been described in the past.

Anti-Anxiety Agents↗
PubMedDate not supplied

Physiological sleep disturbance in children with atopic dermatitis: a case control study.

It is generally acknowledged that sleep disturbance commonly complicates atopic dermatitis (AD), but the nature of this disturbance, including its physiologic aspects, has been little studied, especially in children. The results of home polysomnography (PSG) were compared for 20 school-age children with AD and sex- and age-matched healthy controls. The findings provided objective confirmation of disruption of sleep by both brief and longer awakenings associated with scratching episodes. Sleep efficiency was reduced but other sleep variables were not significantly affected. Home sleep studies offer advantages for further investigation of the factors involved in the link between AD and sleep disturbance, and the assessment of the contribution made by this disturbance to the daytime psychological problems of children with AD.

Adolescent↗
PubMedDate not supplied

A survey of mothers' impressions of seizure precipitants in children with epilepsy.

In a survey of 446 children with epilepsy attending a regional EEG unit, mothers of nearly 90% of the children reported factors that appeared to act as precipitants of their children's seizures. The relationship between these factors and the seizures ranged from consistent triggers to an occasional association. There were no differences in incidence according to sex, site of focus, or type of epilepsy. Associations between environmental events or internal states are so commonly perceived by mothers that routine inquiry would appear warranted. If the event can be corroborated as a seizure precipitant, application of psychological methods of seizure control may be appropriate; if the event cannot be corroborated, needless anxiety about particular situations for a child may be avoided.

Adolescent↗
PubMedDate not supplied

A clinical approach to poorly controlled seizures in children.

Uncontrolled seizures are a serious problem and a source of much anxiety to physicians, parents and others concerned with the care of children with epilepsy. A systematic approach to the causes of poor seizure control, considering basic diagnostic, pharmacological, neurological and psychological factors, can reveal treatment possibilities previously unrecognized.

Anticonvulsants↗
PubMedDate not supplied

Medical student education in sleep and its disorders.

OBJECTIVE: To investigate the pattern of medical student teaching about sleep and its disorders in the UK. DESIGN: A questionnaire was sent to organisers of preclinical and clinical courses in which aspects of sleep and its disorders might appropriately be included. SETTING: All UK medical schools. RESULTS: There was an overall 71% response rate, with all medical schools represented. A wide variation (80-6%) was seen between departments in the provision of such teaching. The median total time given to sleep and its disorders in undergraduate teaching as a whole was five minutes, for preclinical teaching 15 minutes, and zero in clinical teaching. Teaching was particularly limited on the various types of sleep disorder common in clinical practice, and also on non-medication treatments. Little consistency was evident in teaching format, recommended reading, use of other instructional material and student assessment. Awareness of local sleep research or clinics was reported by very few. CONCLUSIONS: As in other countries, undergraduate medical teaching is inadequate as a basis for the development of competence in diagnosing and treating sleep disorders, which are common and cause difficulties in all sections of the population. There is a need to correct this deficiency in ways compatible with recent recommended changes in medical education.

Clinical Competence↗