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Biomedical subjects

G Squadrito

Publications and source records attributed to G Squadrito.

At least 109 records · Page 6Linked to original sources
PubMed1980

[Hypertriglyceridemia, IRI and platelet aggregation].

The Authors have studied in 13 patients with type IV hyperlipoproteinemie the behaviour of platelet aggregation and the response of IRI and blood nefa to an oral glucose load. Only two, in whom it has been possible to evidence a basal hypernefemia and a net hyperinsulinism in response to glucose oral load, showed platelet hyperaggregation to all inducers. These findings suggest that type IV hyperlipoproteinemia does not significantly influence platelet aggregation, in which IRI may have a possible role.

Adult↗
PubMed1980

[Platelet aggregation in normal and hypertensive subjects during cold pressor test].

The Authors have studied, in 5 normal subjects and in 10 with essential arterial hypertension, the behaviour of platelet aggregation before, during and after cold pressor test. It has been possible to evidence, in hypertensive subjects, a greater responsiveness of platelets to adrenaline induced aggregation. The Authors think that such effects may be due to hyperexcitability of sympathetic nervous system, which can regulate the functional behaviour of platelets in response to cold pressor test.

Adenosine Diphosphate↗
PubMed1980

[Calcium and endocrine pancreas secretion. I. Effects of an infusion of calcium on plasma levels of insulin and glucagon].

The authors have investigated the behaviour of IRI, IRG and blood glucose levels during a calcium infusion (15 mg/Kg body weight per 90') and during an equivalent saline infusion, in normal subjects. No evident differences were observed between the two infusions; only a slight but not significant decrease of glucagon levels appeared during calcium administration. Further experiences are clearly required, especially during alpha and beta cells stimulation, to better elucidate relationships between calcium and pancreatic endocrine secretion "in vivo".

Adult↗
PubMed1980

[Calcium and endocrine pancreas secretion. II. Effects of an infusion of calcium on insulin and glucagon secretion induced by intravenous administration of glucose].

IRI, IRG and blood glucose levels after I.V.G.T.T. in normal subjects were not significantly modified when I.V.G.T.T. was repeated during a prolonged calcium infusion (15 mg/Kg body weight per 90'). The Authors advance the hypothesis that no closed relationships exist between serum calcium levels and insulin secretion, in these experimental conditions; with regard to glucagon secretion, further experiences are of course required namely during alpha-cell stimulation.

Adult↗
PubMed1979

[Inhibitory effects of indomethacin on prolactin liberation induced with peptides with opium-like activity].

Indomethacin inhibits prolactin liberating effects by MET-enkefalin-NH2, a synthetic analogue of MET-enkefalin, both in intact and in ovariectomized, estradiol benzoate treated rats. The introduction of PGE1 increases the intensity of this effect. It is therefore possible to suppose that the PGs are involved as intermediaries of the prolactin relasing effect induced by MET-ENH-NH2.

Animals↗
PubMed1979

[Adrenal cortex production of aldosterone "in vitro" caused by angiotensin II: effects of indomethacin].

Angiotensin II increases aldosterone production of isolated and superfused bovine adrenal glands. Indomethacin shows a bi-phasic effect on the production of the above-mentioned hormone, inhibitory at low doses (0,2 microgram/ml), stimulatory at high doses (5.0 microgram/ml). Preincubation with this drug impedes the increase of aldosterone production induced by angiotensin II. It is likely that the steroidogenetic effect of angiotnesin II is carried out through the PGs.

Adrenal Cortex↗
PubMed1979

[Circadian variations in glycemia and IRI in normal subjects, young and adult diabetics and in obese subjects].

Blood sugar and IRI were followed for 24 hr in healthy patients, young and adult diabetics, and in subjects with apparently primary obesity on a standard, normal calorie diet. Morning and nocturnal insulin positivity peaks were noted in the normal subjects, though circadians variations in these parameters were mainly related to meals. This periodicity was altered in young diabetics, for whom insulin responsivity was ruled out, and in the adult diabetics, who displayed deficient insulin secretion in the morning, and delayed secretion after the afternoon meal, and in the obese subjects, the quality of whose response was close to that of the previous group. The usefulness of this type on examination in the planning of diet and drug management, quite apart from diagnosis and prognosis, is stressed.

Blood Glucose↗