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Biomedical subjects

G Simmat

Publications and source records attributed to G Simmat.

14 recordsLinked to original sources

[The blink reflex and the diagnosis of multiple sclerosis. Clinical correlations in 66 patients].

The blink reflex obtained from 66 patients with multiple sclerosis (MS) shows 73% pathologic responses with MS considered as definite, 50% with MS considered as probable and only 18% with possible MS. These findings are of great diagnostical help, particularly in the absence of clinical evidence of involvement of the brain-stem. Among 8 electrological syndromes of alteration of the blink reflex, those due to large lesions of the brain-stem are often associated with definite MS, but small alterations of the blink reflex are more valuable for multifocal characterisation of the illness.

Blinking↗

[Protein profile and immunoelectrophoresis of cerebrospinal fluid in neurology. Results and etiologies apropos of 430 tests].

The study of 430 cerebrospinal fluids resulting from a neurological department showed 67 pathological medical cases according to following tests: intrathecal IgG synthesis and/or restricted heterogeneity with immuno-electrophoresis. We established a biological classification to approach the different etiologies. This classification was used for multiple sclerosis for which various strictly clinical classifications are not always able to diagnose the illness, as we show it for one of them.

Blood Proteins↗

[Peculiar clinical and x-ray computed tomographic aspects in Sturge-Weber disease. Bilateral occipital calcifications without facial angioma].

Early and specific data on the typical calcifications seen in Sturge-Weber's syndrome are provided by computed tomography. The importance of this investigation is emphasized by the fact that standard radiographs and arteriography do not always produce clearcut results--facial angioma, epilepsy, mental retardation, hemiplegia, hemianopsia--the symptomatology can be less evident and even minimal.

Adolescent↗

[Femoral neuralgia and diabetes. Method of clinical approach].

A retrospective study allowed us to work out an original method for an essentially clinical approach of the correlation between femoral neuropathy and diabetes mellitus. Nine parameters were chosen for this purpose and a score was developed. From this score, three categories were defined: in each, the existence and etiological probability of diabetes mellitus are discussed. This clinical approach is a simple means of establishing more accurate guidelines for complementary investigations.

Diabetes Complications↗

[Spinal cord metastasis of a glioblastoma].

Two years after surgery followed by chemotherapy and radiotherapy of a temporal glioblastoma, a 51 year-old woman presented pluriradicular symptoms ascribed to compression of the left part of the cauda equina. The second operation confirmed the metastatic nature of the compression, and histological investigation proved the similarity of the neoplastic tissues taken from the medullary and cerebral regions. The authors stress the rarity of the clinical forms of medullary metastases of glioblastomas. The factors conducive to this fluid effusion are trauma and ventricular effraction by the original tumour. Neither screening nor prophylactic irradiation seem necessary in view of the low frequency of these metastases.

Brain Neoplasms↗

[Supraventricular arrhythmia in Yersinia enterocolitica infection].

The authors report a case of Yersinia enterocolitica rheumatism which presented atrial arrhythmias similar to those seen in atrial disease, but which resolved after 3 weeks and have not recurred over the subsequent 38 months. This case adds to the list of the cardiac manifestations of yersiniosis and raises the problem of acute forms of auricular disease.

Arrhythmias, Cardiac↗

[Neurologic adverse effects of piperazine].

Piperazine has been used since the end of the nineteenth century as a urine alkalizing agent in gout and more widely in the past thirty years for its antihelmintic properties. It is known for being well tolerated and of low toxicity. However, there are cases, sometimes in particular circumstances, where piperazine causes severe and impressive neurological disorders, which can be totally reversed if the medication is discontinued. The disorders are accompanied by consistent, but similarly reversible, electroencephalographic changes. The etiopathogenesis of these accidents caused by piperazine is discussed.

Aged↗