Biomedical subjects
Publications and source records attributed to G Seidl.
Description of roentgenographic changes in idiopathic pulmonary hemosiderosis and Goodpasture's syndrome. Diagnostic criteria for differentiation from alveolar edema are shown. Separation of disseminated alveolar infections without clinical information is not possible. The close relation to idiopathic pulmonary hemosiderosis and Goodpasture's syndrome is emphasized.
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Since 1984 35 PCA unicondylar endoprostheses of the knee joint were implanted due to unicondylar high grade osteoarthritis or Morbus Ahlbäck. 19 endoprostheses with a minimum follow up of two years were investigated. Three implants had to be changed because of an aseptic loosening and were retrieved for histomorphological analysis. The implants which were found clinically stable were graded from the patients point of view as excellent to fair. Only in 5 cases, however, no seam at the implants interface was found in the radiological screening. These radiological lucencies can only be seen in x-ray amplifier controlled x-rays. No correlation has been seen of the clinical performance to the type of anchorage. The position of the implants which had revision was fair in one case and poor in two cases, although a correlation between the radiological seam and the position of the implant was not found. The histological analysis showed up a well developed osseointegration on the femoral component in the area of the porous coated pegs. At the interface to the bone of the tibial components intervening connective tissue has been found. 3 implants still in function have to be seen as endangered to loosening and further 8 prostheses with partial radiolucencies might become potential failures.
Physical exercise is often recommended as a therapeutic tool to combat pre- and postmenopausal loss of bone density. However, the relationship between training dosage (intensity, duration, frequency) and the effect on bone density still is undergoing discussion. Furthermore, the exercise quantification programs are often described so inadequately that they are neither quantitatively nor qualitatively reproducible. The aim of this investigation was to determine whether a clearly defined training of muscle strength, under defined safety aspects, performed only twice weekly, can counteract bone density loss in women with postmenopausal osteopenia. Data from 16 women in the training group (age, 63.6 +/- 6.2 yr) and 15 women in the control group (age, 67.4 +/-9.7 yr), of comparable height and weight, were evaluated. Strength training was performed for 6 mo as continually adapted strength training, providing an intensity of about 70% of each test person's one repetition maximum. Bone mineral density of lumbar vertebrae 2 to 4 and the femoral neck was measured by dual-energy x-ray absorptiometry. Maximum performance in watts and parameters of hemodynamics were controlled with a bicycle ergometer test to maximal effort. In addition, metabolic data were assessed. In the lumbar spine and femoral neck, the training group showed no significant changes, whereas the control group demonstrated a significant loss of bone mineral density, especially in the femoral neck (P<0.05). The strength increase was highly significant in all exercised muscle groups, rising to about 70% above the pretraining status (P<0.001). Heart rate and blood pressure data indicated a slight economization, metabolism was not significantly influenced. Based on these findings, we conclude that continually adapted strength training is an effective, safe, reproducible, and adaptable method of therapeutic strength training, following only two exercise sessions per week.
Tomography of the sacroiliac joints (SIJ) was performed in 72 patients with rheumatoid arthritis (RA) and in 50 controls. Twenty-seven rheumatoid patients (38%) showed typical sacroilitis with predominantly severe intraarticular ankylosis and subchondral erosions. Fourteen patients (19%) had a probable sacroilitis with mild erosions and intraarticular ankylosis and concomitant degenerative changes. Fifteen patients (21%) showed predominantly degenerative changes and 16 RA patients (22%) had no radiological manifestation of the SIJ. There was no relation between typical sacroilitis and age of patients, duration of disease, rheumatoid factor, Steinbrocker's stage and frequency of HLA B27.