Accelerated synthesis of dopamine-C14 from tyrosine-C14 in rat brain after chlorpromazine.
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Animals↗
Biomedical subjects
G Sedvall
Publications and source records attributed to G Sedvall.
Influence of hypercapnia on the noradrenalin content of sympathetically decentralized and innervated skeletal muscle.
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Animals↗
The effect of chlorpromazine on catecholamine synthesis in rat and mouse brain.
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Animals↗
Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland.
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Animals↗
Effect of some biologically active amines on the cecum wall of germfree rats.
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Acetylcholine↗
Reduction of the monoamine stores in the terminals of bulbospinal neurones following stimulation in the medulla oblongata.
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Animals↗
Adrenergic transmission at vasoconstrictor nerve terminals partially depleted of noradrenaline.
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Animals↗
PET studies of glucose metabolism in patients with schizophrenia.
The hypothesis of abnormal patterns of metabolism in schizophrenia was examined in a series of six young patients with psychotic symptoms satisfying the research diagnostic criteria. After intravenous injection of 11C-glucose obtained through a photosynthetic process, the regional activity of 11C in brain was measured with a four-ring positron camera. Regions of interest were obtained from computed tomographic images. Each patient underwent a second positron emission tomographic examinations after 4-5 weeks of treatment with a neuroleptic drug. No evidence of a hypofrontal pattern was found, but after treatment there was a reduced frontal uptake on the left side compared with temporal regions. The left-right asymmetry in the lentiform nucleus was reduced after treatment.
Acute Disease↗