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Biomedical subjects

G Schwesinger

Publications and source records attributed to G Schwesinger.

131 records · Page 8Linked to original sources
PubMedDate not supplied

The height of the patella: an anatomical study.

The anterior region of the left knee joint of fifty fresh human cadavers (37 males, 13 females) was dissected and the following measurements were carried out: length of the patella (LP), width of the patella (WP), length of the patellar tendon (LT), and width of the patellar tendon (WT). The ratio LT/LP for assessment of the vertical position of the patella was 1.00 (range 0.72-1.38; SD 0.14) and found to be in full agreement with radiographic studies carried out first by Insall and Salvati in 1971 and later by other authors. There was no significant statistical difference between the Insall-Salvati index in males and females. The length and width of the patella as well as the length of the patellar tendon were found to be significantly larger in males than in females (P less than 0.001).

Adolescent↗
PubMedDate not supplied

[Multiple breast fibroadenomas in pregnancy - diagnostics and therapy].

Benign tumours in pregnancy are often "lactating adenomas". The differentiation against malignant processes is sometimes difficult. In this case report we demonstrate the diagnostic and therapeutic procedure in an 18-year old woman with multiple nodes in the right and left breast. Pregnancy makes it difficult to examine the breast with the usual methods. Because of suspect clinical and ultrasonic findings we made a core biopsy already during pregnancy. With nodes in the breast during pregnancy, ultrasound is the diagnostic method of choice. Histology by core biopsy must be made. As long as the histology corresponds with the ultrasound findings, controls are sufficient if the findings are benign. Otherwise, diagnostic exstirpation will be necessary even though the patient is pregnant. Ultrasound and biopsy are the only significant examinations in pregnancy and lactation. Mammography is contraindicated because of radiation. Assessment by palpation and NMR is problematic during pregnancy.

Adolescent↗
PubMedDate not supplied

One hundred years ago: the history of cryptococcosis in Greifswald. Medical mycology in the nineteenth century.

Medico-mycological investigations began at Greifswald in Germany as early as 1842 when Wilhelm Baum (1799-1883) was appointed to the chair of surgery of the university. This is shown by some theses of the time, as well as by the discovery of the contagious nature of pityriasis versicolor by Carl Ferdinand Eichstedt (1816-92), who identified a fungus as the cause (1846), later named Microsporon furfur (C. Robin 1853). In 1868 the physician Karl Friedrich Mosler (1831-1911) published clinical-mycological studies and investigations about animal feeding with yeasts. Some time later (1870) Friedrich Grohé (1830-86) and his assistants, Alwin R.A. Block (1843-?) and M.R. Roth of the Pathological Institute, described the results of transmission studies with 'Aspergillus glaucus, Penicillium glaucum and yeast'. His successor in the chair, Paul Grawitz (1850-1932), also published the results of his own mycological investigations. Finally, on 7 July 1894, at an evening lecture of the Greifswald Medical Society, Abraham Buschke (1868-1943) from the Hospital of Surgery gave a talk 'on a peculiar disease caused by coccidia', which was followed by a talk by the pathologist Otto Busse (1867-1922) on a 'demonstration of a pathogenic coccidia species'. Busse's subsequent publications are the first proper descriptions of cryptococcosis (1894 ff.). However, Cryptococcus neoformans was named after F. Sanfelice, whose results were published later (1895).

Animals↗
PubMedDate not supplied

Non-palpable breast lesions in asymptomatic women: diagnostic value of initial ultrasonography and comparison with mammography.

AIM: This prospective double-blind study was designed to assess (i) if primary breast screening by ultrasonography is capable of detecting breast cancer independent of tissue density and (ii) if the rate of unnecessary biopsies remains acceptable when diagnostics are based on ultrasonography. PATIENTS AND METHODS: Bilateral breast ultrasonography was performed in 448 asymptomatic women as the initial diagnostic method. Sonograms were interpreted using a set of standardized diagnostic criteria. Subsequently, mammograms were obtained. The radiologists reading the mammograms were blinded to the sonographic results. RESULTS: Overall, 3 non-palpable breast cancers were detected by ultrasound and mammography. All 3 ultrasonographically detected breast cancers were smaller than 1 cm (0.7, 0.7, 0.6 cm). All 3 carcinomas were correctly detected by both methods. For ultrasonography, the false positive rate was 1.1% (n=5) and for mammography 0.6% (n=3). When both methods were combined, the rate of unnecessary open biopsies was 1.6% (n=7). The ratio of benign to malignant lesions was 3.7/1. CONCLUSION: Without prior mammography, primary high-resolution breast ultrasonography is capable of detecting non-palpable breast carcinomas in asymptomatic women at an early stage. The rate of unnecessary open biopsies is low and the ratio of benign to malignant biopsies acceptable.

Adult↗