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Biomedical subjects

G Schisano

Publications and source records attributed to G Schisano.

35 records · Page 2Linked to original sources
PubMed1978

The use of antifibrinolytic drugs in aneurysmal subarachnoid hemorrhage.

Antifibrinolytic drugs have been investigated in a series of 58 patients with recent aneurysmal subarachnoid hemorrhage. It is concluded that tranexamic acid (AMCA) provides a rational method for reducing the frequency of recurrences, and that antifibrinolytic treatment is a preliminary to surgical intervention. In the present series, ischemic complications, which often follow aneurysmal hemmorrhage, seem to be of a more serious nature. There is evidence also that hydrocephalus due to adhesive arachnoiditis is a rare occurrence. The last 20 patients of the present series have been treated with very low doses of AMCA associated with parotid kallikrein inhibitor (Trasylol); this dosage has been effective in preventing recurrence and has appeared to be freer from severe side effects.

Adolescent↗
PubMedDate not supplied

Large anterior communicating artery aneurysm with temporal hemianopsia. Case report.

Giant or large anterior communicating artery (ACOA) aneurysms producing bitemporal hemianopsia are extremely rare. A case is presented of an ACOA aneurysm measuring 2 X 1.4 cm with the patient having had a post-traumatic amaurosis of the left eye for many years. Then he had a subarachnoid hemorrhage and subsequently developed impaired vision in the right eye and temporal hemianopsia. The aneurysm was visible on C.T. but disappeared on post-operative scans. Visual acuity improved radically after treatment with neck ligation and opening of the sac.

Angiography↗
PubMedDate not supplied

Space occupying contusions of cerebral lobes after closed brain injury: considerations about 51 cases.

Fifty one cases of space occupying contusions of the brain have been treated between 1967 and 1974. These represented 2.4% of all head injuries. Forty four were surgically treated and only clinically. The total mortality was 50.9% being 91.4% in patients above 50 years of age and 41% in patients below 50. In 66.6% of patients the lesions were localized in the temporal lobes, and two patients had localized cerebellar contusions. Surgery was performed in 44 patients. There were 13 craniectomies and 31 craniotomies. The operative mortality was 54.5%. Mortality was 65.2% in patients operated on within 24 hours of injury, and 12.5% in those operated on more than 72 hours after trauma. Twenty five patients (20 treated surgically and 5 managed clinically) were examined one year after injury. Eighty four percent were in either good or excellent condition.

Adolescent↗
PubMedDate not supplied

Primary non traumatic intracranial hemorrhage: 139 consecutive cases treated at an emergency regional hospital.

We review 139 consecutive cases of primary non-traumatic intracranial hemorrhage observed at the Neurosurgical Division of Pellegrini Hospitals, Naples. We excluded 20 similar cases which were not thoroughly studied. In the region Campania, which has almost five and a half million inhabitants, there are four emergency centres for neurosurgical patients one of which is at the Pellegrini Hospitals in Naples. In our series of 139 patients, 68 (48.92%) had an intracerebral hematoma (CH); while 71 (51.07%) patients had a subarachnoid hemorrhage (SAH). Thirteen cases out of 68 were added to the 71 cases with SAH because they had an arterial aneurysm or an arteriovenous malformation (AVM) which had ruptured both in the subarachnoid space and in the brain. The most frequent cause of CH was arterial hypertension. Out of 84 patients with SAH, 57 (67.85%) had a vascular malformation. Age, sex, presence of vasospasm, gravity of hemorrhage and interval between hemorrhage and neurosurgical observation were studied. Out of 139 cases, 68 (48.92%) were surgically treated. In conclusion, out of 68 operated patients, 48 (70.58%) survived and 20 died; while, out of 71 non-operated patients, 24 (23.80%) survived and 47 died. The survival rate of patients with aneurysms operated on after 14 days from the hemorrhage is 90.47%. The survival rate in patients with CH operated on after the fifth day is 89.47%.

Adolescent↗