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Biomedical subjects

G Sava

Publications and source records attributed to G Sava.

At least 109 records · Page 6Linked to original sources
PubMed1977

Antimetastatic effects of N-diazoacetyl-glycine derivatives in C57BL mice.

When three diazoacetyl-glycine derivatives, N-diazoacetyl-glycine amide (DGA), N-diazoacetyl-glycine hydrazide (DGI), and N-diazoacetyl-glycine ethyl ester (DGE), were tested against Lewis lung carcinoma in C57BL mice, DGA reduced sharply the number and weight of pulmonary metastases; the effects of DGI and DGE were less pronounced. The growth of the primary tumor was reduced slightly by DGA, but the greater effect was produced by DGI. The absence of correlation between the reduction of the growth of the primary implant and the number of lung secondary tumors for the tested compounds indicated that DGA possesses antimetastatic properties.

Animals↗
PubMed1977

[Hemorrhage complications of acute pancreatitis (author's transl)].

The authors report 11 cases of hemorrhage due to vascular ulcerations arising early or late in the course of acute pancreatitis. The seriousness of these hemorrhages, the difficulties of their therapy are pointed out. In all cases, bleeding should be controlled by surgery. Therefore, attention is drawn to the need for prompt laparotomy in all the shocked patients who failed to respond to conservative measures, for in such cases, a fatal outcome may rapidly occur. The respective advantages and inconveniences of the 2 main surgical treatments, ligation of bleeding vessels or pancreatectomy removing the source of bleeding, are discussed, basing on the presently reported cases and the data of the literature.

Acute Disease↗
PubMed1976

[Acute cholecystitis without stones (author's transl)].

The authors report on ten cases of cholecystites without stones. Two were typhic in origin, six apparently primitive, one postoperative and one posttraumatic. They stress the importance of histologic lesions in each of these etiologies and insist on the high frequency of gangrenous forms in postoperative and posttraumatic cases. Previous antibiotherapy deserves no credit. Emergency cholecystectomy remains the best treatment.

Abdominal Injuries↗